Zobrazeno 1 - 10
of 579
pro vyhledávání: '"Karin Jirström"'
Autor:
Gilar Gorji-Bahri, B. Madhu Krishna, Catharina Hagerling, Akira Orimo, Karin Jirström, Konstantinos S. Papadakos, Anna M. Blom
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Cartilage oligomeric matrix protein (COMP), an extracellular matrix glycoprotein, is vital in preserving cartilage integrity. Further, its overexpression is associated with the aggressiveness of several types of solid cancers. Thi
Externí odkaz:
https://doaj.org/article/70cd2d9352ca489783d89fb5d55c6172
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background There is still a profound lack of efficient therapeutic strategies against pancreatic and other periampullary adenocarcinoma. Surgery is seldom possible, leaving palliative chemotherapy the only option for most patients. Chemother
Externí odkaz:
https://doaj.org/article/0d63736a14b845a9989987c448ca1b6e
Autor:
Linnea Huss, Igis Gulz-Haake, Emma Nilsson, Helga Tryggvadottir, Linn Nilsson, Björn Nodin, Karin Jirström, Karolin Isaksson, Helena Jernström
Publikováno v:
Nutrients, Vol 16, Iss 7, p 931 (2024)
Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membran
Externí odkaz:
https://doaj.org/article/fb3cc9c0b2654d1c9d7d51791a848c99
Autor:
Hanna Sartor, Maria Bjurberg, Mihaela Asp, Anna Kahn, Jenny Brändstedt, Päivi Kannisto, Karin Jirström
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Background Imaging ovarian cancer (OC) includes evaluating peritoneal carcinomatosis (PC) and enlarged cardio phrenic lymph nodes (CPLN) by computed tomography (CT), and thorough evaluation is tedious work. A “CT short score” with high-r
Externí odkaz:
https://doaj.org/article/21f9da70c66a4118aff30c276f7481a4
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Periampullary cancer is a term for cancers arising in or in close proximity to the pancreas. Pancreatic cancer is the 3rd leading cause of cancer death for both sexes and while surgery is the only option for cure, chemotherapy is
Externí odkaz:
https://doaj.org/article/3c6f7a0521b94458ac82a62e885a5e4f
Autor:
Anna M. Blom, Chrysostomi Gialeli, Catharina Hagerling, Jonna Berntsson, Karin Jirström, Konstantinos S. Papadakos
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCartilage Oligomeric Matrix Protein (COMP) is an oncogenic protein that has been associated with a decrease in infiltrating T-cells in periampullary adenocarcinoma. This study aimed to investigate whether this is also the case for colorec
Externí odkaz:
https://doaj.org/article/196d7d38f38b48b7aa5ea66fe6f0bbaf
Autor:
Stanley Teleka, Marju Orho-Melander, Fredrik Liedberg, Olle Melander, Karin Jirström, Tanja Stocks
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract There is substantial genetic predisposition to bladder cancer (BC). Recently, blood pressure (BP) was positively associated with BC risk in men, but the potential interaction with genetic susceptibility for BC is unknown. We investigated a w
Externí odkaz:
https://doaj.org/article/038fb0fc799a4b38a012f39a296985ca
Publikováno v:
Cancer Medicine, Vol 11, Iss 15, Pp 2896-2905 (2022)
Abstract Background Smoking has shown interactions with bladder cancer (BC) genetic variants, especially N‐acetyltransferase‐2 (NAT2), a tobacco smoke metabolism gene, on BC risk. The interactions by disease aggressiveness are unknown. Methods We
Externí odkaz:
https://doaj.org/article/11282fd38f45404f9cb2d7e0170862c1
Autor:
Maria C. Svensson, Maja Svensson, Björn Nodin, David Borg, Charlotta Hedner, Claes Hjalmarsson, Karin Leandersson, Karin Jirström
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2022)
Tumor-associated macrophages (TAMs) have emerged as key players in tumor immunology but demonstrate a continuum of functional states being either tumor suppressive or promoting. Moreover, chemotherapeutic agents have been shown to alter the tumor mic
Externí odkaz:
https://doaj.org/article/c40cd281455e4ca2844560d7cd6332d3
Autor:
Artur Mezheyeuski, Max Backman, Johanna Mattsson, Alfonso Martín-Bernabé, Chatarina Larsson, Ina Hrynchyk, Klara Hammarström, Simon Ström, Joakim Ekström, Siarhei Mauchanski, Salome Khelashvili, Amanda Lindberg, Margrét Agnarsdóttir, Per-Henrik Edqvist, Jutta Huvila, Ulrika Segersten, Per-Uno Malmström, Johan Botling, Björn Nodin, Charlotta Hedner, David Borg, Jenny Brändstedt, Hanna Sartor, Karin Leandersson, Bengt Glimelius, Anna Portyanko, Fredrik Ponten, Karin Jirström, Patrick Micke, Tobias Sjöblom
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104452- (2023)
Summary: Background: Cancer immunity is based on the interaction of a multitude of cells in the spatial context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated to fundamentally improve the accuracy in predicting
Externí odkaz:
https://doaj.org/article/21d6bb4dde9a4bcc8ada77b8353d03fb