Rearing environment affects development of the immune system in neonates

Autor: Hauke Smidt, Charlotte F. Inman, Sergey R. Konstantinov, B. G. Miller, CR Harris, Christopher R. Stokes, Karin Haverson, Philip C. Jones, Mick Bailey

Publikováno v: Clinical and Experimental Immunology 160 (2010) 3
Clinical & Experimental Immunology
Clinical and Experimental Immunology, 160(3), 431-439

Summary Early-life exposure to appropriate microbial flora drives expansion and development of an efficient immune system. Aberrant development results in increased likelihood of allergic disease or increased susceptibility to infection. Thus, factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b680f07d370691fb5f8ca72033ac181
https://doi.org/10.1111/j.1365-2249.2010.04090.x

Effect of Oral Antigen and Antibody Exposure at Birth on Subsequent Immune Status

Autor: Philip H. Jones, Martin Kenny, Gaynor Corfield, Karin Haverson, Mick Bailey, B. G. Miller, Jenny Fowler, Christopher R. Stokes

Publikováno v: International Archives of Allergy and Immunology. 150:192-204

Background: The purpose of this work was to investigate the effects of early low-level exposure to either antigen or antibody alone on subsequent immune responses in entirely immunologically naïve animals. This is impossible in species with a permea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03f01578f2dc84a80563a3b65a27ecbb
https://doi.org/10.1159/000218123

Antigen presenting cells in mucosal sites of veterinary species

Autor: Sabine Riffault, Karin Haverson

Publikováno v: Veterinary Research
Veterinary Research, BioMed Central, 2006, 37 (3), pp.339-358. ⟨10.1051/vetres:2006005⟩
Veterinary Research 3 (37), 339-358. (2006)

International audience; The ability of antigen presenting cells, in particular dendritic cells, to integrate a variety of environmental signals, together with their ability to respond appropriately by initiating either tolerance or defensive immune r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9259b9b0394c9eeefd79902cd3d7e8ed
https://doi.org/10.1051/vetres:2006005

The larynx as an immunological organ: immunological architecture in the pig as a large animal model

Autor: Karin Haverson, Martin A. Birchall, Mick Bailey, Christopher R. Stokes, EV Barker

Publikováno v: Clinical and Experimental Immunology. 143:6-14

Summary The larynx is a mucosal organ positioned at the divergence of the respiratory and digestive tracts. It is exposed to a wide variety of environmental components, including foreign antigens, tobacco smoke, laryngopharyngeal reflux and pollutant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf02062e9907fb7daf2b8f5c504ce509
https://doi.org/10.1111/j.1365-2249.2005.02950.x

The influence of environment on development of the mucosal immune system

Autor: B. G. Miller, Christopher R. Stokes, Charlotte F. Inman, Karin Haverson, Mick Bailey, GC Corfield, CR Harris, Philip C. Jones

Publikováno v: Veterinary Immunology and Immunopathology. 108:189-198

The mucosal immune system expresses active responses against pathogens and also tolerance against harmless food and commensal bacterial antigens. The mechanisms that determine which of these outcomes occur after recognition of antigens by T-cells are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151d1d8adacc1d5fd05f0e52db164c28
https://doi.org/10.1016/j.vetimm.2005.07.010