Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Karin Hauser"'
Autor:
Niccolò Mosesso, Niharika Savant Lerner, Tobias Bläske, Felix Groh, Shane Maguire, Marie Laura Niedermeier, Eliane Landwehr, Karin Vogel, Konstanze Meergans, Marie-Kristin Nagel, Malte Drescher, Florian Stengel, Karin Hauser, Erika Isono
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Autophagy is relevant for diverse processes in eukaryotic cells, making its regulation of fundamental importance. The formation and maturation of autophagosomes require a complex choreography of numerous factors. The endosomal sorting comple
Externí odkaz:
https://doaj.org/article/acc1afb476b74f8ba81b36323c4b875f
Autor:
Karin Vogel, Tobias Bläske, Marie-Kristin Nagel, Christoph Globisch, Shane Maguire, Lorenz Mattes, Christian Gude, Michael Kovermann, Karin Hauser, Christine Peter, Erika Isono
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The endocytic degradation of plasma membrane proteins can be modulated by deubiquitylating enzymes (DUBs). Here, the authors describe two plasma membrane localized Arabidopsis DUBs that can be activated by binding to anionic lipids and influence the
Externí odkaz:
https://doaj.org/article/e31b4e70945b43d6a26752c15f71c864
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The mechanism of PARP1-dependent poly-ADP-ribosylation in response to DNA damage is still under debate. Here, the authors use ATR-FTIR spectroscopy to provide time-resolved insights into the molecular details of this process under near physiological
Externí odkaz:
https://doaj.org/article/1616d84778de4c2386df75ff6b8c0ab3
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1067 (2021)
The 140 amino acid protein α-synuclein (αS) is an intrinsically disordered protein (IDP) with various roles and locations in healthy neurons that plays a key role in Parkinson’s disease (PD). Contact with biomembranes can lead to α-helical confo
Externí odkaz:
https://doaj.org/article/e892040a41c34825bb6e59ba511ade0a
Publikováno v:
Biophysical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84b4c0a4b6aef6ff191892bf8ba9964
https://doi.org/10.1016/j.bpj.2023.05.019
https://doi.org/10.1016/j.bpj.2023.05.019
Publikováno v:
The Journal of Chemical Physics. 158
Membranes are crucial for the functionality of membrane proteins in several cellular processes. Time-resolved infrared (IR) spectroscopy enables the investigation of interaction-induced dynamics of the protein and the lipid membrane. The photorecepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1123a97ea796dc854255f4a76ce3b742
https://doi.org/10.1063/5.0139808
https://doi.org/10.1063/5.0139808
Autor:
Ho-Wah Siu, Karin Hauser
Publikováno v:
The journal of physical chemistry letters. 13(20)
Polyglutamine (polyQ) diseases are caused by misfolding and aggregation of expanded polyQ tracts in the affected protein. PolyQ fibrils have been studied in detail; however, less is known about oligomeric precursor states. By a combination of time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc45464219363f8236f6b35b7f352a4
https://pubmed.ncbi.nlm.nih.gov/35580015
https://pubmed.ncbi.nlm.nih.gov/35580015
Publikováno v:
Faraday discussions. 235
In experimental studies, heavy water (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::082515392596cf48ffcf044c7c421689
https://pubmed.ncbi.nlm.nih.gov/35388817
https://pubmed.ncbi.nlm.nih.gov/35388817
Publikováno v:
European Journal of Mineralogy. 31:231-236
Biomedical applications of calcium carbonate minerals have been receiving an increasing amount of attention. With a simple chemical composition, low production cost, and ease to produce in large quantities, this non-toxic (bio)mineral has been used p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224017370f4f534cd7e4670bfb47239e
https://doi.org/10.1127/ejm/2019/0031-2831
https://doi.org/10.1127/ejm/2019/0031-2831
Autor:
Mohammad A. Fallah, Karin Hauser
Publikováno v:
Biomaterials Science. 7:3204-3212
The intrinsically disordered Parkinson disease protein α-synuclein (αS) performs conformational changes induced by intermolecular protein-protein as well as by protein-membrane interactions. Aggregation of αS is a hallmark for the disease, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28477669267219ae0c5614490b7f3192
https://doi.org/10.1039/c9bm00140a
https://doi.org/10.1039/c9bm00140a