Výsledky vyhledávání - "Karin Hartog"

Akademický článek

Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein.

Autor: Aemro Kassa, Antu K Dey, Pampi Sarkar, Celia Labranche, Eden P Go, Daniel F Clark, Yide Sun, Avishek Nandi, Karin Hartog, Heather Desaire, David Montefiori, Andrea Carfi, Indresh K Srivastava, Susan W Barnett

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76139 (2013)

Entry of HIV-1 into target cells requires binding of the viral envelope glycoprotein (Env) to cellular receptors and subsequent conformational changes that culminates in fusion of viral and target cell membranes. Recent structural information has rev

Externí odkaz: https://doaj.org/article/b7c0af66bfd14154b3573bb1a9e8c474

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Akademický článek

Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein.

Autor: Antu K Dey, Brian Burke, Yide Sun, Klara Sirokman, Avishek Nandi, Karin Hartog, Ying Lian, Anthony R Geonnotti, David Montefiori, Michael Franti, Grégoire Martin, Andrea Carfi, Pascal Kessler, Loïc Martin, Indresh K Srivastava, Susan W Barnett

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30233 (2012)

The identification of HIV-1 envelope glycoprotein (Env) structures that can generate broadly neutralizing antibodies (BNAbs) is pivotal to the development of a successful vaccine against HIV-1 aimed at eliciting effective humoral immune responses. To

Externí odkaz: https://doaj.org/article/8de4cde9f4c94164b95e696ae0582869

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Limited Antibody‐Dependent Cellular Cytotoxicity Antibody Response Induced by a Herpes Simplex Virus Type 2 Subunit Vaccine

Autor: Andria G. M. Langenberg, Steve Kohl, Rose E. Sekulovich, Cheryl Goldbeck, Karin Hartog, Edwin D. Charlebois, Rae Lyn Burke, Mavash Sigouroudinia

Publikováno v: The Journal of Infectious Diseases. 181:335-339

The humoral response to a herpes simplex virus (HSV) type 2 subunit vaccine containing recombinant glycoproteins B (gB 2 ) and D (gD 2 ) was tested in 3 groups of patients. These included HSV-seronegative, HSV-1-seropositive, and HSV-2-seropositive i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6098832330eaf90a6d98fe0d22d9d6df
https://doi.org/10.1086/315208

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Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein

Autor: Celia C. LaBranche, Aemro Kassa, Avishek Nandi, Indresh K. Srivastava, Eden P. Go, Yide Sun, Pampi Sarkar, Heather Desaire, Daniel F. Clark, Antu K. Dey, Susan W. Barnett, Karin Hartog, Andrea Carfi, David C. Montefiori

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76139 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ecdd99b5e1c178eff1a8c6209a743e
http://europepmc.org/articles/PMC3797752?pdf=render

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Rationally designed HIV envelope glycoproteins delivered in a novel adjuvant elicited more broadly reactive antigen-specific antibody responses

Autor: Andrea Carfi, Indresh K. Srivastava, A Kassa, Antu K. Dey, Celia C. LaBranche, Karin Hartog, Susan W. Barnett, Avishek Nandi, David C. Montefiori, Yide Sun

Publikováno v: Retrovirology
Retrovirology, Vol 9, Iss Suppl 2, p P18 (2012)

Methods Here, we designed disulfide-stabilized recombinant HIV1 subtype B (SF162) envelope glycoproteins (Env), gp120 and gp140, by insertion of site-specific cysteine pairs between two layers (layer 1 and 2) in inner domain of gp120. In addition, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6b170795d4da50d674e634dd34aee9
https://doi.org/10.1186/1742-4690-9-s2-p18

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Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein

Autor: Loïc Martin, Indresh K. Srivastava, Antu K. Dey, Karin Hartog, Brian Burke, Michael Franti, Avishek Nandi, Andrea Carfi, Anthony R. Geonnotti, Ying Lian, Pascal Kessler, Yide Sun, Susan W. Barnett, Klara Sirokman, Grégoire Martin, David C. Montefiori

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (1), pp.e30233. ⟨10.1371/journal.pone.0030233⟩
PLoS ONE, Vol 7, Iss 1, p e30233 (2012)
PLoS ONE, 2012, 7 (1), pp.e30233. ⟨10.1371/journal.pone.0030233⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01d1596d51a05cabae26f183322d186
https://hal-cea.archives-ouvertes.fr/cea-02530537

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Use of a polyanionic carbomer, Carbopol971P, in combination with MF59, improves antibody responses to HIV-1 envelope glycoprotein

Autor: Yide Sun, Susan W. Barnett, Brian Burke, Antu K. Dey, Indresh K. Srivastava, David C. Montefiori, Karin Hartog, Jonathan L. Heeney

Publikováno v: Vaccine. 30(17)

Identification of optimal antigen(s) and adjuvant combination(s) to elicit potent, protective, and long-lasting immunity has been a major challenge for the development of effective vaccines against chronic viral pathogens, such as HIV-1, for which th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a047a0fa7e28bffb81cf4dd76ca5c22
https://pubmed.ncbi.nlm.nih.gov/22366638

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Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates

Autor: Yide Sun, Elaine Kan, Brian Burke, Leonidas Stamatatos, Indresh K. Srivastava, Jimna Cisto, Susan Hilt, Susan W. Barnett, Ying Lian, R. Holland Cheng, Karin Hartog, Jeffrey B. Ulmer, Zohar Biron, Victoria Sharma

Publikováno v: Virology. 372(2)

We previously reported that an envelope (Env) glycoprotein immunogen (o-gp140DeltaV2SF162) containing a partial deletion in the second variable loop (V2) derived from the R5-tropic HIV-1 isolate SF162 partially protected vaccinated rhesus macaques ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622d2b71984992543362522af9844558
https://pubmed.ncbi.nlm.nih.gov/18061231

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Induction of herpes simplex virus gB-specific cytotoxic T lymphocytes in TAP1-deficient mice by genetic immunization but not HSV infection

Autor: Xavier Paliard, Barbara Doe, Alexander Y. Lee, Christopher M. Walker, Mark Selby, Rae Lyn Burke, Karin Hartog

Publikováno v: Virology. 282(1)

Loading of most endogenous peptides on major histocompatibility complex class I molecules is conditional on their transport into the endoplasmic reticulum (ER) by the peptide transporter TAP. We describe an HSV-2/1 cross-reactive cytotoxic T-cell (CT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65218ded8fc126fab611adb4b7509e7c
https://pubmed.ncbi.nlm.nih.gov/11259190

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Corrigendum to 'Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates' [Virology 372 (2008) 273–290]

Autor: Jeffrey B. Ulmer, R. Holland Cheng, Zohar Biron, Yide Sun, Brian Burke, Indresh K. Srivastava, Victoria Sharma, Karin Hartog, Ruben Diaz-Avalos, Ying Lian, Jimna Cisto, Elaine Kan, Susan W. Barnett, Leonidas Stamatatos, Susan Hilt

Publikováno v: Virology. 381:287

Corrigendum to “Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates” [Virology 372 (2008) 273–290] Indresh K. Srivastava ⁎, Elaine Kan , Yide Sun , Victoria A. Sharma , Jimna Cisto , Brian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac25ded9003d09df779eda83723e44c
https://doi.org/10.1016/j.virol.2008.09.005

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