Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Karin H Nilsson"'
Autor:
Karin H. Nilsson, Petra Henning, Jianyao Wu, Klara Sjögren, Ulf H. Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Osteoporosis is a common skeletal disease affecting millions of individuals world-wide, with an increased risk of fracture, and a decreased quality of life. Despite its well-known consequences, the etiology of osteoporosis and optimal treatm
Externí odkaz:
https://doaj.org/article/1b8d0e49a68646e08722bc6248ae8098
Autor:
Yiwen Jiang, Karin Horkeby, Petra Henning, Jianyao Wu, Lina Lawenius, Cecilia Engdahl, Priti Gupta, Sofia Movérare-Skrtic, Karin H. Nilsson, Ellis Levin, Claes Ohlsson, Marie K. Lagerquist
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Estradiol (E2) affects both reproductive and non-reproductive tissues, and the sensitivity to different doses of E2 varies between tissues. Membrane estrogen receptor α (mERα)-initiated signaling plays a tissue-specific role in mediating E
Externí odkaz:
https://doaj.org/article/d2771fc646b5432c9142e280d23828b5
Autor:
Sofia Movérare-Skrtic, Jakob Voelkl, Karin H. Nilsson, Maria Nethander, Trang Thi Doan Luong, Ioana Alesutan, Lei Li, Jianyao Wu, Karin Horkeby, Marie K. Lagerquist, Antti Koskela, Juha Tuukkanen, Jon H. Tobias, Ulf H. Lerner, Petra Henning, Claes Ohlsson
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104546- (2023)
Summary: Background: Global sclerostin inhibition reduces fracture risk efficiently but has been associated with cardiovascular side effects. The strongest genetic signal for circulating sclerostin is in the B4GALNT3 gene region, but the causal gene
Externí odkaz:
https://doaj.org/article/dcd0ba5afbb847689c3ed1feff4c91de
Autor:
Karin H. Nilsson, Petra Henning, Maha El Shahawy, Maria Nethander, Thomas Levin Andersen, Charlotte Ejersted, Jianyao Wu, Karin L. Gustafsson, Antti Koskela, Juha Tuukkanen, Pedro P. C. Souza, Jan Tuckermann, Mattias Lorentzon, Linda Engström Ruud, Terho Lehtimäki, Jon H. Tobias, Sirui Zhou, Ulf H. Lerner, J. Brent Richards, Sofia Movérare-Skrtic, Claes Ohlsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Genetic association signals for fractures have been reported at the RSPO3 locus, but the causal gene and the underlying mechanism are unknown. Here, the authors show that RSPO3 exerts an important role for vertebral trabecular bone mass and bone stre
Externí odkaz:
https://doaj.org/article/bb0475854da041a2990d5eeb48bf5cee
Autor:
Karin L Gustafsson, Sofia Movérare-Skrtic, Helen H Farman, Cecilia Engdahl, Petra Henning, Karin H Nilsson, Julia M Scheffler, Edina Sehic, Ulrika Islander, Ellis Levin, Claes Ohlsson, Marie K Lagerquist
Publikováno v:
Journal of Endocrinology. 253:75-84
Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ER) agonists or antagonists in a tissue-specific manner. ERs exert effects via nuclear actions but can also utilize membrane-initiated signaling pathways. To determine if membra
Autor:
Sofia Movérare-Skrtic, Jakob Voelkl, Karin H. Nilsson, Maria Nethander, Trang Thi Doan Luong, Ioana Alesutan, Lei Li, Jianyao Wu, Karin Horkeby, Marie K. Lagerquist, Antti Koskela, Juha Tuukkanen, Jon H. Tobias, Ulf H. Lerner, Petra Henning, Claes Ohlsson
Publikováno v:
eBioMedicine
BACKGROUND: Global sclerostin inhibition reduces fracture risk efficiently but has been associated with cardiovascular side effects. The strongest genetic signal for circulating sclerostin is in the B4GALNT3 gene region, but the causal gene is unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcbf3393e2dfe11d968d63b75cb3418
https://europepmc.org/articles/PMC10102813/
https://europepmc.org/articles/PMC10102813/
Autor:
Lina Lawenius, Karin L. Gustafsson, Jianyao Wu, Karin H. Nilsson, Sofia Movérare-Skrtic, Eric M. Schott, Maria J. Soto-Girón, Gerardo V. Toledo, Klara Sjögren, Claes Ohlsson
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 322:E344-E354
The gut microbiome has the capacity to regulate bone mass. The aim of this study was to develop a nutritional synbiotic dietary assemblage at an optimal dose to maintain bone mass in ovariectomized (Ovx) mice. We performed genomic analyses and in vit
Autor:
Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Maha El Shahawy, Antti Koskela, Juha Tuukkanen, Jan Tuckermann, Petra Henning, Ulf H. Lerner, Claes Ohlsson, Sofia Movérare-Skrtic
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 322:E211-E218
Osteoporosis is an age-dependent serious skeletal disease that leads to great suffering for the patient and high social costs, especially as the global population reaches higher age. Decreasing estrogen levels after menopause result in a substantial
Autor:
Maha El Shahawy, Pedro P. C. Souza, Karin H Nilsson, Thais Floriano-Marcelino, Ulf H. Lerner, Anna Westerlund, Petra Henning, Sofia Movérare-Skrtic, Claes Ohlsson
Publikováno v:
Journal of Inflammation Research
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Petra Henning,1 Sofia Movérare-Skrtic,1 Anna Westerlund,1 Pedro Paulo Chaves de Souza,2,3 Thais Floriano-Marcelino,3 Karin H Nilsson,1 Maha El Shahawy,1,4 Claes Ohlsson,1 Ulf H Lerner1 1Department of Internal Medicine and Clinical Nutrition, Insti
Autor:
Anna E. Törnqvist, Karin H Nilsson, Thomas Funck-Brentano, Louise Grahnemo, Claes Ohlsson, Sofia Movérare-Skrtic
Publikováno v:
Calcified Tissue International
Epidemiological studies have shown that high bone mineral density (BMD) is associated with an increased risk of osteoarthritis (OA), but the causality of this relationship remains unclear. Both bone mass and OA have been associated with the WNT signa