The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non‐coding RNA and synonymous mutations

Autor: Karin Fröse, Miriam Linsenmeier, Julia C. Berkmann, Jana Heitmann, Lino Möhrmann, Gjendine Voss, Philipp Karschnia, Sven Diederichs, Deetje Iggena, Caroline Hoppe, Lorenz Bartsch, Maria E Weinberger, Paula Röpenack, Johannes Morstein, Timo Rückert, Anna Steinmann, Stella V Paffenholz, Ludger Sandig, Ramona Wullenkord, Jacqueline Wasmuth, Danny Jazmati, Maximilian Schell, Thomas Maulhardt

Publikováno v: Diederichs, S, Bartsch, L, Berkmann, J C, Fröse, K, Heitmann, J, Hoppe, C, Iggena, D, Jazmati, D, Karschnia, P, Linsenmeier, M, Maulhardt, T, Möhrmann, L, Morstein, J, Paffenholz, S V, Röpenack, P, Rückert, T, Sandig, L, Schell, M, Steinmann, A, Voss, G, Wasmuth, J, Weinberger, M E & Wullenkord, R 2016, ' The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations ', EMBO Molecular Medicine, vol. 8, no. 5, pp. 442-57 . https://doi.org/10.15252/emmm.201506055
EMBO Molecular Medicine

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor‐specific mutations not only in protein‐coding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e689fba1ebc81913434045610d3eb18a
https://doi.org/10.15252/emmm.201506055