Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Karin Fehsel"'
Autor:
Karin Fehsel
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2294 (2024)
Metabolic syndrome (MetS) is the most common adverse drug reaction from psychiatric pharmacotherapy. Neuroreceptor blockade by the antipsychotic drug clozapine induces MetS in about 30% of patients. Similar to insulin resistance, clozapine impedes Ak
Externí odkaz:
https://doaj.org/article/093981f28b3c47c280018d4e85e8fe89
Autor:
Karin Fehsel, Marie-Luise Bouvier, Loredana Capobianco, Paola Lunetti, Bianca Klein, Marko Oldiges, Marc Majora, Stefan Löffler
Publikováno v:
Cells, Vol 13, Iss 9, p 762 (2024)
The antipsychotic drug clozapine demonstrates superior efficacy in treatment-resistant schizophrenia, but its intracellular mode of action is not completely understood. Here, we analysed the effects of clozapine (2.5–20 µM) on metabolic fluxes, ce
Externí odkaz:
https://doaj.org/article/b7043f18258d4c7b8a1c3fe0c3ddc3ba
Autor:
Marie-Luise Bouvier, Karin Fehsel, Andrea Schmitt, Eva Meisenzahl-Lechner, Wolfgang Gaebel, Martina von Wilmsdorff
Publikováno v:
BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Patients with liver diseases often have some form of anemia. Hematological dyscrasias are known side effects of antipsychotic drug medication and the occurrence of agranulocytosis under clozapine is well described. However, the se
Externí odkaz:
https://doaj.org/article/d4754b467a2648e39b87ca741a052710
Autor:
Karin Fehsel
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2421 (2023)
Impaired iron metabolism has been increasingly observed in many diseases, but a deeper, mechanistic understanding of the cellular impact of altered iron metabolism is still lacking. In addition, deficits in neuronal energy metabolism due to reduced g
Externí odkaz:
https://doaj.org/article/5b7fc396644d4c06881103067e20bdc2
Autor:
Marie‐Luise Bouvier, Karin Fehsel, Andrea Schmitt, Eva Meisenzahl‐Lechner, Wolfgang Gaebel, Martina vonWilmsdorff
Publikováno v:
Brain and Behavior, Vol 10, Iss 8, Pp n/a-n/a (2020)
Abstract Objective Sex‐dependent disturbances of peripheral glucose metabolism are known complications of antipsychotic drug treatment. The influence of long‐term clozapine and haloperidol medication on hypothalamus, maintaining aspects of intern
Externí odkaz:
https://doaj.org/article/9223ac9dd3fd4da09fe21ca7ae1ea973
Autor:
Tobias Lautwein, Georg Winterer, Sarah Tschirner, David Schafflick, René Deenen, Carsten Korth, Laura Hecher, Andrea Schmitt, Irina Papazova, Karin Fehsel, Alkomiet Hasan, Karl Köhrer, Ovidiu Popa, Gerd Meyer zu Hörste, Peter Falkai, Berend Malchow, Svenja V. Trossbach
Publikováno v:
Translational Psychiatry, Vol 9, Iss 1, Pp 1-16 (2019)
Translational Psychiatry
Translational Psychiatry
Currently, the clinical diagnosis of schizophrenia relies solely on self-reporting and clinical interview, and likely comprises heterogeneous biological subsets. Such subsets may be defined by an underlying biology leading to solid biomarkers. A tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8385779fc353b5ff9ef0b27d4c848d
https://opus.bibliothek.uni-augsburg.de/opus4/files/70075/s41398-019-0486-6.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/70075/s41398-019-0486-6.pdf
Autor:
Andrea Vierkötter, Thomas Schulte, Tamara Schikowski, Mohammed Voussoughi, Dorothea Sugiri, Christian Herder, Michaela Jänner, Karin Fehsel, Christian Luckhaus, Ursula Krämer, Tom Teichert, Anke Hüls
Publikováno v:
Journal of Neural Transmission. 123:1369-1379
Genetic and environmental risk factors contribute to the pathogenesis of Alzheimer’s dementia. Besides known genetic risk factors like the apolipoprotein (APO) Ee4 allele, single nuclear polymorphisms (SNPs) of the estrogen receptors (ESRs) are can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f9f1a5a0d6adb6c802f25bff06221d
https://doi.org/10.1007/s00702-016-1620-8
https://doi.org/10.1007/s00702-016-1620-8
Autor:
Svenja V. Trossbach, Uwe Henning, M. Angelica De Souza Silva, Sandra Schäble, Christian Luckhaus, Carsten Korth, Karin Fehsel, Georg Winterer
Publikováno v:
Behavioural Brain Research. 275:176-182
The Disrupted-in-Schizophrenia 1 (DISC1) protein plays a key role in behavioral control and vulnerability for mental illnesses, including schizophrenia. In this study we asked whether peripheral DISC1 protein levels in lymphocytes of patients diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959bcfe4ad65121d08a23c0c87a45965
https://doi.org/10.1016/j.bbr.2014.08.064
https://doi.org/10.1016/j.bbr.2014.08.064
Autor:
Anke Hüls, Karin Fehsel, Tamara Schikowski, Ursula Krämer, Andrea Vierkötter, Christian Luckhaus, Sabine Stolz, Christian Herder
Publikováno v:
ISEE Conference Abstracts. 2016
Introduction: Long-term airborne particle exposure has been associated with chronic inflammation providing a link to long-term health effects of particulate matter (PM). We recently showed an assoc...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fdcc5c1f5edc3de5bfd7eae6d4597ae
https://doi.org/10.1289/isee.2016.3151
https://doi.org/10.1289/isee.2016.3151
Autor:
Tamara Schikowski, Dorothee Sugiri, Il-seok Bae, Nicole Probst-Hensch, Lilian Tzivian, Andrea Vierkötter, Tom Teichert, Ursula Krämer, Ulrich Ranft, Christian Luckhaus, Thomas Schulte, Mohammad Vossoughi, Karin Fehsel, Barbara Hoffmann, Christian Herder
Publikováno v:
Environmental research. 142
Background Epidemiological studies have shown effects of long-term exposure to air pollution on cardiovascular and respiratory health. However, studies investigating the effects of air pollution on cognition and brain function are limited. We investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d7fc63c863f0e5d02e7e516c4df5be
https://pubmed.ncbi.nlm.nih.gov/26092807
https://pubmed.ncbi.nlm.nih.gov/26092807