Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karin E. Norgard"'
Autor:
Rakesh Vig, Rakesh K. Jain, Ajit Varki, Karin E. Norgard-Sumnicht, Khushi L. Matta, Andrea Koenig
Publikováno v:
Glycobiology. 7:79-93
Selectins interact with glycoconjugate ligands in important normal and pathological situations. While high affinity recognition of natural ligands is associated with alpha 1-3(4)fucosylated, alpha 2-3sialylated (and/or sulfated) lactosamine sequences
Publikováno v:
Science. 261:480-483
L-Selectin is a calcium-dependent mammalian lectin that mediates lymphocyte trafficking by recognizing sialylated ligands on high endothelial venules in lymph nodes. Although L-selectin probably mediates neutrophil extravasation into nonlymphoid tiss
Autor:
Sandra Diaz, Kevin L. Moore, S Ushiyama, Karin E. Norgard, N L Stults, Richard D. Cummings, R P McEver, Ajit Varki
Publikováno v:
Journal of Biological Chemistry. 268:12764-12774
Lectin-carbohydrate recognition between the selectins and their ligands are among the earliest events in leukocyte recirculation, leukocyte recruitment into inflamed areas, and abnormal egress of leukocytes in diseases. Previously, we have described
Publikováno v:
Glycobiology. 10(7)
In the preceding article (Manzi,A.E., Norgard-Sumnicht,K., Argade,S., Marth,J.D., van Halbeek,H. and Varki.A. [2000] GLYCOBIOLOGY:, 10, 669-688), we reported a comprehensive approach for the extraction, fractionation, and isolation of all of the majo
Autor:
Adriana E. Manzi, Jamey D. Marth, Herman van Halbeek, Ajit Varki, Sulabha P Argade, Karin E. Norgard-Sumnicht
Publikováno v:
Glycobiology. 10(7)
The production of mice with genetic alterations in glycosyltransferases has highlighted the need to isolate and study complex mixtures of the major classes of oligosaccharides (glycans) from intact tissues. We have found that nano-NMR spectroscopy of
The selectins are calcium-dependent C-type lectins that bind certain sialylated, fucosylated, sulfated glycoprotein ligands. L-selectin also recognizes endothelial proteoglycans in a calcium-dependent manner, via heparan sulfate (HS) glycosaminoglyca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeedf53dd0c70cc9529f3218bff4c77
https://europepmc.org/articles/PMC508636/
https://europepmc.org/articles/PMC508636/
Autor:
Adriana E. Manzi, Ajit Varki, Derek Toomre, Linda Roux, Karin E. Norgard-Sumnicht, Hudson H. Freeze
Publikováno v:
The Journal of biological chemistry. 270(46)
We previously described a diverse family of sulfated anionic N-linked oligosaccharides released by peptide: N-glycosidase F (PNGaseF) from calf pulmonary artery endothelial (CPAE) cells (Roux, L., Holoyda, S., Sundblad, G., Freeze, H.H., and Varki, A
Autor:
Ajit Varki, Karin E. Norgard-Sumnicht
Publikováno v:
The Journal of biological chemistry. 270(20)
We earlier reported calcium-dependent, heparin-like L-selectin ligands in cultured bovine endothelial cells (Norgard-Sumnicht, K. E., Varki, N. M., and Varki, A. (1993) Science 261,480-483). Here we show that these are heparan sulfate proteoglycans (
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(3)
The selectins are adhesion receptors that play key roles in leukocyte trafficking. Each has an N-terminal C-type lectin domain that binds to specific carbohydrates in a calcium-dependent manner. L-selectin recognizes sulfated, sialylated ligands on l