Výsledky vyhledávání - "Karin E. Norgard"

Calcium-Dependent Heparin-Like Ligands For L-Selectin in Nonlymphoid Endothelial Cells

Autor: Karin E. Norgard-Sumnicht, Ajit Varki, Nissi Varki

Publikováno v: Science. 261:480-483

L-Selectin is a calcium-dependent mammalian lectin that mediates lymphocyte trafficking by recognizing sialylated ligands on high endothelial venules in lymph nodes. Although L-selectin probably mediates neutrophil extravasation into nonlymphoid tiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c50013456af7cf352b1bb4469781c14
https://doi.org/10.1126/science.7687382

Zobrazit plný text záznamu

Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharides

Autor: Sandra Diaz, Kevin L. Moore, S Ushiyama, Karin E. Norgard, N L Stults, Richard D. Cummings, R P McEver, Ajit Varki

Publikováno v: Journal of Biological Chemistry. 268:12764-12774

Lectin-carbohydrate recognition between the selectins and their ligands are among the earliest events in leukocyte recirculation, leukocyte recruitment into inflamed areas, and abnormal egress of leukocytes in diseases. Previously, we have described

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97d2a234d1cbd399a0b61e92c00d9aeb
https://doi.org/10.1016/s0021-9258(18)31454-6

Zobrazit plný text záznamu

Exploring the outcome of genetic modifications of glycosylation in cultured cell lines by concurrent isolation of the major classes of vertebrate glycans

Autor: Xiaomei Bai, Adriana E. Manzi, Jeffrey D. Esko, Karin E. Norgard-Sumnicht, Ajit Varki

Publikováno v: Glycobiology. 10(7)

In the preceding article (Manzi,A.E., Norgard-Sumnicht,K., Argade,S., Marth,J.D., van Halbeek,H. and Varki.A. [2000] GLYCOBIOLOGY:, 10, 669-688), we reported a comprehensive approach for the extraction, fractionation, and isolation of all of the majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40dbc7f5759c043b2e0d62f75bc1a48a
https://pubmed.ncbi.nlm.nih.gov/10910973

Zobrazit plný text záznamu

Exploring the glycan repertoire of genetically modified mice by isolation and profiling of the major glycan classes and nano-NMR analysis of glycan mixtures

Autor: Adriana E. Manzi, Jamey D. Marth, Herman van Halbeek, Ajit Varki, Sulabha P Argade, Karin E. Norgard-Sumnicht

Publikováno v: Glycobiology. 10(7)

The production of mice with genetic alterations in glycosyltransferases has highlighted the need to isolate and study complex mixtures of the major classes of oligosaccharides (glycans) from intact tissues. We have found that nano-NMR spectroscopy of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e4541a87fd64cf9bb74f4a71c01368
https://pubmed.ncbi.nlm.nih.gov/10910972

Zobrazit plný text záznamu

Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents

Autor: Karin E. Norgard-Sumnicht, Ajit Varki, Andrea Koenig, Robert J. Linhardt

The selectins are calcium-dependent C-type lectins that bind certain sialylated, fucosylated, sulfated glycoprotein ligands. L-selectin also recognizes endothelial proteoglycans in a calcium-dependent manner, via heparan sulfate (HS) glycosaminoglyca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aeedf53dd0c70cc9529f3218bff4c77
https://europepmc.org/articles/PMC508636/

Zobrazit plný text záznamu

Unusual anionic N-linked oligosaccharides from bovine lung

Autor: Adriana E. Manzi, Ajit Varki, Derek Toomre, Linda Roux, Karin E. Norgard-Sumnicht, Hudson H. Freeze

Publikováno v: The Journal of biological chemistry. 270(46)

We previously described a diverse family of sulfated anionic N-linked oligosaccharides released by peptide: N-glycosidase F (PNGaseF) from calf pulmonary artery endothelial (CPAE) cells (Roux, L., Holoyda, S., Sundblad, G., Freeze, H.H., and Varki, A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdfc6a7e5a8d7c71229a388e71a66e7
https://pubmed.ncbi.nlm.nih.gov/7499228

Zobrazit plný text záznamu

Endothelial heparan sulfate proteoglycans that bind to L-selectin have glucosamine residues with unsubstituted amino groups

Autor: Ajit Varki, Karin E. Norgard-Sumnicht

Publikováno v: The Journal of biological chemistry. 270(20)

We earlier reported calcium-dependent, heparin-like L-selectin ligands in cultured bovine endothelial cells (Norgard-Sumnicht, K. E., Varki, N. M., and Varki, A. (1993) Science 261,480-483). Here we show that these are heparan sulfate proteoglycans (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b9b24fddd423ae4205f01ae590a381
https://pubmed.ncbi.nlm.nih.gov/7538130

Zobrazit plný text záznamu

Enhanced interaction of L-selectin with the high endothelial venule ligand via selectively oxidized sialic acids

Autor: Ajit Varki, Hui-Ling Han, Nissi Varki, Karin E. Norgard, Leland D. Powell, Michael Kriegler

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 90(3)

The selectins are adhesion receptors that play key roles in leukocyte trafficking. Each has an N-terminal C-type lectin domain that binds to specific carbohydrates in a calcium-dependent manner. L-selectin recognizes sulfated, sialylated ligands on l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056fe35d4e99ce1c8ce12a14280adc3e
https://pubmed.ncbi.nlm.nih.gov/7679216

Zobrazit plný text záznamu

Akademický článek

Calcium-dependent heparin-like ligands for L-selectin in non-lymphoid endothelial cells.

Autor: Norgard-Sumnich, Karin E., Varki, Nissi M.

Publikováno v: Science. 7/23/1993, Vol. 261 Issue 5120, p480. 4p. 2 Color Photographs, 3 Black and White Photographs, 1 Chart, 9 Graphs.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání