Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karin Dott"'
Autor:
Adrian Allan, Lorraine Dobbie, Genevieve Stapleton, Jan-Åke Gustafsson, Ling Wang, Jonathan R. Seckl, Richard Lathe, Kenneth Andrew Rose, Eva Hedlund, Cécile Martin, Karin Dott, Stephan Gauldie
Publikováno v:
Journal of Biological Chemistry. 276:23937-23944
The major adrenal steroid dehydroepiandrosterone (DHEA) enhances memory and immune function but has no known dedicated receptor; local metabolism may govern its activity. We described a cytochrome P450 expressed in brain and other tissues, CYP7B, tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01044af0c7ea76e042d72d467858fa4c
https://doi.org/10.1074/jbc.m011564200
https://doi.org/10.1074/jbc.m011564200
Autor:
Michel Geist, Jean-Marc Balloul, Danièle Spehner, Catherine Houssais-Pêcheur, Fabienne Proamer, Maria-Antonietta Zanta, Karin Dott, Robert Drillien
Publikováno v:
Virology. 273(1):9-15
Modified vaccinia virus Ankara (MVA) is a highly attenuated virus strain that may be useful as a vaccine vector. Ultrastructural examination of purified MVA showed that most of the viral particles are enveloped in contrast to the Copenhagen strain (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eee827d093d9db7e282f66855db76d5
Autor:
Claudine Mazurier, Sylvie Jorieux, Dominique Meyer, P. Meulien, Michael Courtney, M. Nishino, Geneviève Piétu, A. Pavirani, Karin Dott, D. Oufkir, Jean-Pierre Girma
Publikováno v:
Thrombosis and Haemostasis. 67:154-160
SummaryThe cloning of the cDNA encoding von Willebrand factor (vWF) has revealed that it is synthesized as a large precursor (pre-pro-vWF) molecule and it is now clear that the prosequence or vWAgll is responsible for the intracellular multimerizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d5b9a142c8ab2b6205992b73e67bcd9
https://doi.org/10.1055/s-0038-1648398
https://doi.org/10.1055/s-0038-1648398
Publikováno v:
Virology. 176:413-425
The nef protein is one of the regulatory proteins encoded by the human immunodeficiency virus (HIV). It has been shown to down-regulate viral transcription and displays features typical of some membrane-associated G proteins. To define the amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a26632af716d6b02a347e3ac03e92d
https://doi.org/10.1016/0042-6822(90)90011-f
https://doi.org/10.1016/0042-6822(90)90011-f
Autor:
Wilfried Dalemans, Pascal Barbry, Guy Champigny, Sophie Jallat, Karin Dott, Dominique Dreyer, Ronald G. Crystal, Andréa Pavirani, Jean-Pierre Lecocq, Michel Lazdunski
Publikováno v:
Nature. 354:526-528
Cystic fibrosis is associated with a defect in epithelial chloride ion transport which is caused by mutations in a membrane protein called CFTR (cystic fibrosis transmembrane conductance regulator). Heterologous expression of CFTR produces cyclicAMP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5bd168526f285f9ed7f138b697a06d6
https://doi.org/10.1038/354526a0
https://doi.org/10.1038/354526a0
Autor:
Karin Dott, M Lazdunski, Pascal Barbry, Valentin K. Gribkoff, J. Hinnrasky, Wilfried Dalemans, J.-L. Imler, Guy Champigny, Edith Puchelle, Andrea Pavirani
Publikováno v:
Pascal Barbry
Europe PubMed Central
Europe PubMed Central
The effects of the mild cystic fibrosis (CF) mutation P574H were analysed and compared with those of three severe ones (delta I507, delta F508 and R560T). Immunochemical and functional analyses indicate that the rank order of CFTR expression at the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b332515f7db1fcc7639fc4b1373f201
https://europepmc.org/articles/PMC398355/
https://europepmc.org/articles/PMC398355/
Autor:
G. Rautmann, Marc Alizon, Luc Montagnier, Anne Laurent, D. Schmitt, M. P. Kieny, Jean-Pierre Lecocq, Karin Dott, M. Girard, Simon Wain-Hobson, S. Chamaret
Publikováno v:
Nature Biotechnology. 4:790-795
Lymphadenopathy–associated virus is the causative agent of AIDS, the acquired immunodeficiency syndrome. A retrovirus of the lentivirus group, LAV carries a single major target antigen at its surface: the env protein. We have introduced the env cod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf886accbafaf690fb5d180fae726bb
https://doi.org/10.1038/nbt0986-790
https://doi.org/10.1038/nbt0986-790
Autor:
Fabienne Schamber, Karin Dott, Jean-Pierre Cazenave, Claudine Mazurier, Andrea Pavirani, Marie-Louise Wiesel, Jean-Pierre Lecocq, Huguette Harrer, Yves Piquet, Pierre Meulien, Hendrik Van de Pol, Yves Cordier, Dominique Villeval
Publikováno v:
Nature Biotechnology. 5:389-392
The recent molecular cloning of factor VIII (FVIII or antihaemophilic factor)1–3 has brought new hope to haemophilia A patients of a safer therapeutic preparation. The choice of a host cell for the expression of such a large and unstable protein4 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49b331726f24994a0692b861f6f7de90
https://doi.org/10.1038/nbt0487-389
https://doi.org/10.1038/nbt0487-389
Autor:
Fabienne Mischler, Claudine Mazurier, Marie-Louise Wiesel, Andrea Pavirani, Jean-Pierre Cazenave, Pierre Meulien, Huguette Harrer, Jean-Pierre Lecocq, Karin Dott
Publikováno v:
Biochemical and Biophysical Research Communications. 145:234-240
Using recombinant DNA technology, the NH2 and COOH terminal domains of the human Factor VIII molecule were co-expressed in baby hamster kidney 21 (BHK21) cells using the vaccinia virus system. Procoagulant activity was detectable in cell supernatants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6668e0d2ad7cb6f82d46053b08da40a3
https://doi.org/10.1016/0006-291x(87)91311-8
https://doi.org/10.1016/0006-291x(87)91311-8
Autor:
Pierre Meulien, Thérèse Faure, Fabienne Mischler, Huguette Harrer, Pascale Ulrich, Brigitte Bouderbala, Karin Dott, Martine Sainte Marie, Claudine Mazurier, Marie-Louise Wiesel, Hendrik van de Pol, Jean-Pierre Cazenave, Mkhael Courtney, Andrea Pavirani
Publikováno v:
"Protein Engineering, Design and Selection". 2:301-306
We have constructed new B domain deletion derivatives of human factor VIII (FVIII) by manipulating the cDNA using recombinant DNA techniques. One of these new derivatives, FVIII delta II, in which amino acids 771(pro)-1666(asp) have been deleted, no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e4d176c66a74339c91fa459e95d5bb
https://doi.org/10.1093/protein/2.4.301
https://doi.org/10.1093/protein/2.4.301