Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Karin D. Scarpinato"'
Autor:
Aksana Vasilyeva, Jill E. Clodfelter, Michael J. Gorczynski, Anthony R. Gerardi, S. Bruce King, Freddie Salsbury, Karin D. Scarpinato
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Mismatch repair proteins modulate the cytotoxicity of several chemotherapeutic agents. We have recently proposed a “death conformation” of the MutS homologous proteins that is distinguishable from their “repair conformation.” This conformatio
Externí odkaz:
https://doaj.org/article/9dcf76a2d46946c4ba5aba5171c200da
Publikováno v:
Advances in clinical chemistry. 60
Normal cell function requires strict control over the repair of DNA damage, which prevents excessive mutagenesis. An enhanced accumulation of mutations results in the multistep process generally known as carcinogenesis. Defects in repair pathways fue
Autor:
Natalie R Gassman, Jill E Clodfelter, Anita K McCauley, Keith Bonin, Freddie R Salsbury, Karin D Scarpinato
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17907 (2011)
Human mismatch repair proteins MSH2-MSH6 play an essential role in maintaining genetic stability and preventing disease. While protein functions have been extensively studied, the substantial amino-terminal region (NTR*) of MSH6 that is unique to euk
Externí odkaz:
https://doaj.org/article/e611ffec021a49cd852cb1bcd002ac7f