Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karin C. Lilja"'
Autor:
Nan Zhang, Julen Mendieta-Esteban, Alessandro Magli, Karin C. Lilja, Rita C. R. Perlingeiro, Marc A. Marti-Renom, Aristotelis Tsirigos, Brian David Dynlacht
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Chromatin structure and topology play important roles in the regulation of gene expression. Here the authors study the spatio-temporal re-organization of promoter-enhancer interactions in pluripotent ES and skeletal muscle stem cells and the correspo
Externí odkaz:
https://doaj.org/article/c1124748dba1487d92994b14a058a001
Autor:
Jayhun Lee, Sangjo Kang, Karin C. Lilja, Keegan J. Colletier, Cornelia Johanna Franziska Scheitz, Ying V. Zhang, Tudorita Tumbar
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Changes in global histone trimethylation have been linked to embryonic but not adult stem cell plasticity. Here, Lee et al. find H3 K4/K9/K27me3 levels actively reduced in adult mouse skin and hair follicle stem cells during quiescence (catagen) and
Externí odkaz:
https://doaj.org/article/c0f2eaaa2ce7421fa4a9eca52ccf4ad0
Autor:
Karin C Lilja, Nan Zhang, Alessandro Magli, Volkan Gunduz, Christopher J Bowman, Robert W Arpke, Radbod Darabi, Michael Kyba, Rita Perlingeiro, Brian D Dynlacht
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176190 (2017)
Pluripotent stem cells (PSC) hold great promise for the treatment of human skeletal muscle diseases. However, it remains challenging to convert PSC to skeletal muscle cells, and the mechanisms by which the master regulatory transcription factor, Pax7
Externí odkaz:
https://doaj.org/article/ff5142d41f5a41b9be3f6295abfd4b22
Autor:
Marc A. Marti-Renom, Alessandro Magli, Karin C. Lilja, Rita C.R. Perlingeiro, Julen Mendieta-Esteban, Brian David Dynlacht, Nan Zhang, Aristotelis Tsirigos
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Using Hi-C, promoter-capture Hi-C (pCHi-C), and other genome-wide approaches in skeletal muscle progenitors that inducibly express a master transcription factor, Pax7, we systematically characterize at high-resolution the spatio-temporal re-organizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7faf16126af2aa95f24e8e1b255836
https://pubmed.ncbi.nlm.nih.gov/33277476
https://pubmed.ncbi.nlm.nih.gov/33277476
Autor:
Andreas Kloetgen, Alcida Karz, Karin C. Lilja, Maria Gabriela Berzoti-Coelho, Varshini Vasudevaraja, Beatriz Sánchez-Sendra, Jochen Imig, Iannis Aifantis, Douglas Hanniford, Rana S. Moubarak, Veronica Davalos, Tommaso Tabaglio, Alejandro Ulloa-Morales, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Carlos Monteagudo, Ernesto Guccione, Pamela Wu
Publikováno v:
Cancer Research. 80:PR04-PR04
Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms governing metastatic spread may uncover new biology and/or yield promising therapeutic insights. Here we investigated the role of circular RNAs (circRNAs), a class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46d08fbd25b2c928e3551733c03db378
https://doi.org/10.1158/1538-7445.mel2019-pr04
https://doi.org/10.1158/1538-7445.mel2019-pr04
Autor:
Rana S. Moubarak, Andreas Kloetgen, Iannis Aifantis, Pamela Wu, Beatriz Sánchez-Sendra, Carlos Monteagudo, Maria Gabriela Berzoti-Coelho, Ernesto Guccione, Veronica Davalos, Tommaso Tabaglio, Varshini Vasudevaraja, Alejandro Ulloa-Morales, Iman Osman, Karin C. Lilja, Aristotelis Tsirigos, Eva Hernando, Douglas Hanniford, Alcida Karz, Diana Argibay, Jochen Imig
Publikováno v:
Cancer Cell
Summary Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms governing metastatic spread may uncover important tumor biology and/or yield promising therapeutic insights. Here, we investigated the role of circular RNAs (c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9d30833ab06c08405bcb1d753c54cc
https://pubmed.ncbi.nlm.nih.gov/31935372
https://pubmed.ncbi.nlm.nih.gov/31935372
Autor:
Michael Kyba, Karin C. Lilja, Volkan Gunduz, Radbod Darabi, Christopher Bowman, Rita C.R. Perlingeiro, Nan Zhang, Brian David Dynlacht, Alessandro Magli, Robert W. Arpke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176190 (2017)
PLoS ONE, Vol 12, Iss 4, p e0176190 (2017)
Pluripotent stem cells (PSC) hold great promise for the treatment of human skeletal muscle diseases. However, it remains challenging to convert PSC to skeletal muscle cells, and the mechanisms by which the master regulatory transcription factor, Pax7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417681bf715905ca2251020c9939e789
https://pubmed.ncbi.nlm.nih.gov/28441415
https://pubmed.ncbi.nlm.nih.gov/28441415
Autor:
Keegan J. Colletier, Tudorita Tumbar, Ying V. Zhang, Jayhun Lee, Sangjo Kang, Cornelia Johanna Franziska Scheitz, Karin C. Lilja
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications
Nature Communications
Mechanisms of plasticity to acquire different cell fates are critical for adult stem cell (SC) potential, yet are poorly understood. Reduced global histone methylation is an epigenetic state known to mediate plasticity in cultured embryonic SCs and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da3f864e0968cbf708a47f01e25fff7
https://doi.org/10.1038/ncomms11278
https://doi.org/10.1038/ncomms11278
Publikováno v:
The Journal of Cell Biology
Runx1 controls timing of adult HSFC and short-term progenitor emergence in the embryonic epithelium and HFSC differentiation and long-term skin integrity in embryonic mesenchyme.
Runx1 controls hematopoietic stem cell emergence and hair follicle
Runx1 controls hematopoietic stem cell emergence and hair follicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c869c65846bb81b3ee5249842cb6a66a
https://doi.org/10.1083/jcb.201006068
https://doi.org/10.1083/jcb.201006068
Autor:
Charlene S. L. Hoi, Brian S. White, Song Eun Lee, Jayhun Lee, David Shalloway, Karin C. Lilja, Tudorita Tumbar
Mechanisms of tissue stem cell (SC) quiescence control are important for normal homeostasis and for preventing cancer. Cyclin-dependent kinase inhibitors (CDKis) are known inhibitors of cell cycle progression. We document CDKis expression in vivo dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f056c2b70b658957bb2fdeabf22ff7
https://europepmc.org/articles/PMC3606971/
https://europepmc.org/articles/PMC3606971/
