Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Karin Bink"'
Autor:
Axel Walch, Karin Bink, Peter Gais, Stefan Stangl, Peter Hutzler, Michaela Aubele, James Mueller, Heinz Höfler, Martin Werner
Publikováno v:
Analytical Cellular Pathology, Vol 20, Iss 1, Pp 25-32 (2000)
Amplifiction of the Her-2/neu gene is accompanied by overexpression of its cell surface receptor product, c‐erbB‐2 protein. To investigate the degree of intratumoural heterogeneity we applied immunohistochemistry in primary Barrett’s adenocarci
Externí odkaz:
https://doaj.org/article/0493ec65ec0642efa047ca66b01af4f1
Autor:
Julia Slotta-Huspenina, Ina Koch, Laurence de Leval, Gisela Keller, Margit Klier, Karin Bink, Marcus Kremer, Mark Raffeld, Falko Fend, Leticia Quintanilla-Martinez
Publikováno v:
Haematologica, Vol 97, Iss 9 (2012)
Background Mantle cell lymphoma is a clinically heterogeneous disease characterized by overexpression of cyclin D1 protein. Blastoid morphology, high proliferation, and secondary genetic aberrations are markers of aggressive behavior. Expression prof
Externí odkaz:
https://doaj.org/article/9ac963b9839249c2a5fc66c4384043af
Autor:
Karin Bink, Eugenia Haralambieva, Marcus Kremer, German Ott, Christine Beham-Schmid, Laurence de Leval, Suat Cheng Peh, Hubert R. Laeng, Uta Jütting, Peter Hutzler, Leticia Quintanilla-Martinez, Falko Fend
Publikováno v:
Haematologica, Vol 93, Iss 4 (2008)
Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma. Since cytogenetic data on extramedullary plasmacytoma are lacking, we studied 38 cases of this type of neoplasm by fluorescence in situ hybrid
Externí odkaz:
https://doaj.org/article/ef0c8aea43d649e0861f53b773652f7f
Autor:
Karin Bink, Ina Koch, Margit Klier, Julia Slotta-Huspenina, Falko Fend, Gisela Keller, Marcus Kremer, Leticia Quintanilla-Martinez, Mark Raffeld, Laurence de Leval
Publikováno v:
Haematologica, vol. 97, no. 9, pp. 1422-1430
Haematologica 97, 1422-1430 (2012)
Haematologica 97, 1422-1430 (2012)
Background Mantle cell lymphoma is a clinically heterogeneous disease characterized by overexpression of cyclin D1 protein. Blastoid morphology, high proliferation, and secondary genetic aberrations are markers of aggressive behavior. Expression prof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9626a3645fe43284e11060bf0e64cdcf
https://doi.org/10.3324/haematol.2011.055715
https://doi.org/10.3324/haematol.2011.055715
Autor:
Falko Fend, Leticia Quintanilla-Martinez, Chris M. Bacon, Teresa A Vela-Chávez, Karin Bink, Patrick Adam, Geetha Menon, Judith A. Ferry, Marcus Kremer, Elaine S. Jaffe
Publikováno v:
Leukemia & Lymphoma. 52:458-466
The aims of this study were to analyze the incidence and morphology of cyclin D1+ DLBCL and cases of Richter transformation (RT), and to elucidate possible molecular mechanisms of cyclin D1 overexpression. Seventy-two cases of de novo DLBCL and 12 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b542f04c97409ae09e3bec9242e9fa
https://doi.org/10.3109/10428194.2010.540361
https://doi.org/10.3109/10428194.2010.540361
Autor:
Jens Krugmann, Manfred Richter, Ina Koch, Leticia Quintanilla-Martinez, Falko Fend, Julia Slotta-Huspenina, Karin Bink, Katja Specht, Marcus Kremer
Publikováno v:
Leukemia Research. 32:79-88
Multiple myeloma (MM) frequently shows overexpression of cyclin D1, either due to a t(11;14)(q13;q32) translocation, or in association with polysomy 11. The predominant expression of a cyclin D1 mRNA isoform lacking the 3'-untranslated region (Delta3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40140ed820e2b12feee5525bf69fbf92
https://doi.org/10.1016/j.leukres.2007.05.021
https://doi.org/10.1016/j.leukres.2007.05.021
Autor:
Elenore Samson, Karin Bink, Heinz Höfler, Jochen Graw, Natalia S. Pellegata, Heide Siggelkow, Falko Fend, Michael J. Atkinson, Leticia Quintanilla-Martinez
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 103, 15558-15563 (2006)
MENX is a recessive multiple endocrine neoplasia-like syndrome in the rat. The tumor spectrum in MENX overlaps those of human multiple endocrine neoplasia (MEN) types 1 and 2. We mapped the MenX locus to the distal part of rat chromosome 4, excluding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da68273d019c52d98948d9cc6826b6b
https://doi.org/10.1073/pnas.0603877103
https://doi.org/10.1073/pnas.0603877103
Autor:
Karin Bink, Peter Gais, Martin Werner, Anja Pickhard, Miriam K. Steuer-Vogt, Rudolf Reiter, Axel Walch, Uta Jütting, Sandra Rauser, Silke Lassmann, Heinz Höfler
Publikováno v:
Clinical Cancer Research. 12:5136-5141
Purpose: Aurora kinase A (AURKA/STK15/BTAK) encodes a serine/threonine kinase associated with chromosomal distribution and its up-regulation induces chromosomal instability, thereby leading to aneuploidy and cell transformation in several types of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c2b7d34868133cb82ca55fb88fd7d5
https://doi.org/10.1158/1078-0432.ccr-05-1650
https://doi.org/10.1158/1078-0432.ccr-05-1650
Autor:
Martin Werner, Jörg Rüdiger Siewert, Michaela Aubele, Hubert J. Stein, Karin Bink, Axel Walch, H. Braselmann, Katja Specht, Horst Zitzelsberger, Heinz Höfler, M. Bauer
Publikováno v:
Laboratory Investigation. 81:791-801
The importance of alterations of the Her-2/neu oncogene in the tumorigenesis of Barrett's adenocarcinoma (BCA) is discussed controversially. In the present study, we evaluated for the first time the Her-2/neu status in the metaplasia-dysplasia-adenoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d400386aa039d176bd795c0e501aff4c
https://doi.org/10.1038/labinvest.3780289
https://doi.org/10.1038/labinvest.3780289
Autor:
Peter Hutzler, Herbert Braselmann, J. Mueller, Karin Bink, Martin Werner, Horst Zitzelsberger, Jochen Bruch, Axel Walch, Jörg Rüdiger Siewert, Hubert J. Stein, Heinz Höfler, Michaela Aubele
Publikováno v:
Modern Pathology. 13:814-824
Lymph node metastasis is one of the strongest negative prognostic factors for patients with Barrett's adenocarcinoma (BCA). However, despite the importance of the metastatic process in BCA, the molecular basis of it remains poorly understood. To sear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e9bf83606f0b640edb300841cc410a
https://doi.org/10.1038/modpathol.3880143
https://doi.org/10.1038/modpathol.3880143