Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Karin B, Busch"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Several human diseases, including cancer and neurodegeneration, are associated with excessive mitochondrial fragmentation. In this context, mitochondrial division inhibitor (Mdivi-1) has been tested as a therapeutic to block the fission-rela
Externí odkaz:
https://doaj.org/article/13b8eb4c4627437394a757350780e95c
Autor:
Binyamin Duethorn, Fabian Groll, Bettina Rieger, Hannes C. A. Drexler, Heike Brinkmann, Ludmila Kremer, Martin Stehling, Marie-Theres Borowski, Karina Mildner, Dagmar Zeuschner, Magdalena Zernicka-Goetz, Marc P. Stemmler, Karin B. Busch, Juan M. Vaquerizas, Ivan Bedzhov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How pluripotency transcription factors regulate the cellular architecture and energetics has remained largely unknown. Here the authors identify Lima1 as a key effector that mediates the pluripotency control of membrane dynamics and cellular metaboli
Externí odkaz:
https://doaj.org/article/ec59b98c93f041c9b516251c4f4d904c
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1075 (2023)
Mitochondria play a major role in ROS production and defense during their life cycle. The transcriptional activator PGC-1α is a key player in the homeostasis of energy metabolism and is therefore closely linked to mitochondrial function. PGC-1α res
Externí odkaz:
https://doaj.org/article/6338ea18def7421b93feeff6c981729e
Autor:
Bettina Rieger, Sven Thierbach, Miriam Ommer, Finja S.V. Dienhart, Susanne Fetzner, Karin B. Busch
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 3, Pp 188-202 (2020)
Abstract Pseudomonas aeruginosa is a Gram‐negative bacterium of the proteobacteria class, and one of the most common causes of nosocomial infections. For example, it causes chronic pneumonia in cystic fibrosis patients. Patient sputum contains 2‐
Externí odkaz:
https://doaj.org/article/7d2b62f3991144eb853ec21d1f0a9200
Autor:
Tasnim Arroum, Marie-Theres Borowski, Nico Marx, Frank Schmelter, Martin Scholz, Olympia Ekaterini Psathaki, Michael Hippler, José Antonio Enriquez, Karin B. Busch
Publikováno v:
Biological Chemistry. 404:399-415
The orchestrated activity of the mitochondrial respiratory or electron transport chain (ETC) and ATP synthase convert reduction power (NADH, FADH2) into ATP, the cell’s energy currency in a process named oxidative phosphorylation (OXPHOS). Three ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::756ebd67a3cb2cf44a9cb32cd1431cd7
https://doi.org/10.1515/hsz-2022-0309
https://doi.org/10.1515/hsz-2022-0309
Autor:
Karin B. Busch
Publikováno v:
BIOspektrum. 28:586-589
Mitochondria are enveloped by an outer membrane (OM) and possess a highly complex inner membrane (IM) with multiple cristae invaginations. We asked how the dynamics of the receptor Tom20 in the OM and ATP synthase in the IM would be affected by the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd491e67c5f482525aa9aadcd272d8b
https://doi.org/10.1007/s12268-022-1830-6
https://doi.org/10.1007/s12268-022-1830-6
Autor:
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
Publikováno v:
The EMBO Journal
Mitochondria are increasingly recognized as cellular hubs to orchestrate signaling pathways that regulate metabolism, redox homeostasis, and cell fate decisions. Recent research revealed a role of mitochondria also in innate immune signaling; however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c63f16f190b57183474e40cd162e641
https://doi.org/10.15252/embj.2022112006
https://doi.org/10.15252/embj.2022112006
Autor:
Ilaria Piccini, Karin Klingel, Hiteshika Gosain, Stefan Peischard, Boris Greber, Britta Eggers, Bettina Rieger, Guiscard Seebohm, Karin B. Busch, Stephan Ludwig, Ivan Liashkovich, Wolfgang A. Linke, Frank U. Müller, Nathalie Strutz-Seebohm, Albrecht Röpke, Katrin Marcus, Huyen Tran Ho
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
A detailed description of pathophysiological effects that viruses exert on their host is still challenging. For the first time, we report a highly controllable viral expression model based on an iPS-cell line from a healthy human donor. The establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c49b66709af2f15857e048617cdc5a3
http://link.springer.com/article/10.1038/s41598-020-72966-9
http://link.springer.com/article/10.1038/s41598-020-72966-9
Autor:
Maniraj Bhagawati, Simon Hoffmann, Katharina S. Höffgen, Henning D. Mootz, Jacob Piehler, Karin B. Busch
Publikováno v:
Angewandte Chemie (International Ed. in English)
Protein semi‐synthesis inside live cells from exogenous and endogenous parts offers unique possibilities for studying proteins in their native context. Split‐intein‐mediated protein trans‐splicing is predestined for such endeavors and has see
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c21652b2a0084321c5ae85ab7289e0
https://doi.org/10.1002/anie.202006822
https://doi.org/10.1002/anie.202006822
Autor:
Zhixiao Wu, Lena A. Berlemann, Verian Bader, Dominik Sehr, Eva Eilers, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B. Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C. Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B. Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F. Winklhofer
SUMMARYMitochondria are increasingly recognized as cellular hubs to orchestrate signaling pathways that regulate metabolism, redox homeostasis, and cell fate decisions. Recent research revealed a role of mitochondria also in innate immune signaling,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ff740e9a14981cdd6798b61dd0ae3c
https://hdl.handle.net/11577/3456968
https://hdl.handle.net/11577/3456968
