Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karin Ahlman"'
Publikováno v:
Vaccine. 28:5768-5773
Haemophilus ducreyi causes genital ulceration (chancroid), a sexually transmitted infection and still an important factor which contributes to the spread of HIV in developing countries. The bacterium produces a cytolethal distending toxin (HdCDT) cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21c59da3413f13ace0b1144c0d45035
https://doi.org/10.1016/j.vaccine.2010.06.032
https://doi.org/10.1016/j.vaccine.2010.06.032
Publikováno v:
APMIS. 118:143-149
The Haemophilus ducreyi cytolethal distending toxin (HdCDT) catalytic subunit CdtB has DNase-like activity and mediates DNA damage after its delivery into target cells. We constructed a replication-deficient adenovirus type 5 (Ad5) vector expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad95bb6f3dcf12c9ae018e99198b61f
https://doi.org/10.1111/j.1600-0463.2009.02573.x
https://doi.org/10.1111/j.1600-0463.2009.02573.x
Publikováno v:
Microbes and Infection. 11:352-360
Haemophilus ducreyi , the chancroid-causing bacterium, produces lipooligosaccharides (HdLOS) that comprise 5–11 partially sialylated monosaccharides. Subcutaneous immunisation of mice with 5 μg of HdLOS purified from H. ducreyi strains 4438 and 74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474074e8193eaf38928b75271b33a909
https://doi.org/10.1016/j.micinf.2008.12.014
https://doi.org/10.1016/j.micinf.2008.12.014
Autor:
Teresa Lagergård, Jozef Azem, Catharina Wising, Karin Ahlman, Madeleine Zetterberg, Liselott A. Svensson
Publikováno v:
Toxicon. 45:767-776
We investigated the impact of highly purified Haemophilus ducreyi cytolethal distending toxin (HdCDT) on the apoptosis and necrosis of various human cells; including myeloid cells, epithelial cells, keratinocytes, and primary fibroblasts. The levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaa7ff7a8eb77ca4ba51b5002d12e6b
https://doi.org/10.1016/j.toxicon.2005.01.016
https://doi.org/10.1016/j.toxicon.2005.01.016
Autor:
Judica Mbwana, Vivian Sundaeus, Gunnar Dahlén, Hinda J. Ahmed, Teresa Lagergård, Karin Ahlman, Eligius Lyamuya
Publikováno v:
Microbial Pathogenesis. 35:133-137
Antibodies specific for the cytolethal-distending toxin of Haemophilus ducreyi (HdCDT) complex and for the CdtA, CdtB, and CdtC components were measured by ELISA in the sera of 50 patients with culture and/or PCR proven chancroid, 42 patients with pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e229f59e48aec2b59751c1449e7b369d
https://doi.org/10.1016/s0882-4010(03)00111-6
https://doi.org/10.1016/s0882-4010(03)00111-6
Autor:
Judica Mbwana, Teresa Lagergård, Liselott A. Svensson, Eva Gunnarsson, Fred Mhalu, Hinda J. Ahmed, Karin Ahlman, Chalamilla Guerino
Publikováno v:
Sexually Transmitted Diseases. 30:114-119
Background: The etiological agent is usually not established in cases of genital ulcer disease (GUD) in Tanzania, since diagnosis and treatment of this disease are based mainly on clinical rather than micro-biologic parameters. GUD increases the risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081001d6e6d7caddac15efb4cdca79a6
https://doi.org/10.1097/00007435-200302000-00004
https://doi.org/10.1097/00007435-200302000-00004
Autor:
Hinda J. Ahmed, Liselott A. Svensson, Ing-Marie Jonsson, Catharina Wising, Teresa Lagergård, Lena Mölne, Karin Ahlman, Vivianne Sundaeus
Publikováno v:
Microbial Pathogenesis. 33:49-62
The cytolethal distending toxin of Haemophilus ducreyi (HdCDT) is a three-component toxin that induces the arrest of the mammalian cell cycle in the G2 phase. All of the individual gene products, CdtA, CdtB and CdtC, are required for toxic activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdd9f5bde3ae0b50a854599b1eafdf3
https://doi.org/10.1006/mpat.2002.0516
https://doi.org/10.1006/mpat.2002.0516
Autor:
Liselott A. Svensson, Hinda J. Ahmed, Anders Frisk, Karin Ahlman, Teresa Lagergård, Michael Lebens, Catharina Johansson
Publikováno v:
Microbial Pathogenesis. 30:313-324
Cytolethal distending toxin of Haemophilus ducreyi (HdCDT) is a multicomponent toxin, encoded by an operon consisting of three genes, cdtABC . To investigate the role of the individual products in generation of toxicity, recombinant plasmids were con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490a688f7189985541cc1d79d9a65be6
https://doi.org/10.1006/mpat.2000.0436
https://doi.org/10.1006/mpat.2000.0436
Publikováno v:
Microbes and infection. 7(5-6)
Haemophilus ducreyi, the etiologic agent of the sexually transmitted disease chancroid, produces a cytolethal distending toxin (HdCDT) that inhibits cultured cell proliferation, leading to cell death. A rabbit model of dermal infection was used to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0633854fb289fa53bfc0d94ab30a432
https://pubmed.ncbi.nlm.nih.gov/15876546
https://pubmed.ncbi.nlm.nih.gov/15876546
Autor:
Hinda J. Ahmed, Catharina Johansson, Karin Ahlman, Liselott A. Svensson, Margareta Verdrengh, Teresa Lagergård
Publikováno v:
Infection and immunity. 70(2)
We investigated the phagocytosis of Haemophilus ducreyi both in vitro and in vivo. Human granulocyte and monocyte phagocytosis of opsonized and nonopsonized, fluorescence-labeled H. ducreyi was assessed by flow cytometry. Both Escherichia coli and no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9de75f4bf887ab6883710a0656157a
https://pubmed.ncbi.nlm.nih.gov/11796625
https://pubmed.ncbi.nlm.nih.gov/11796625