Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karin A Saunders"'
Autor:
Georgina L Hold, Susan Berry, Karin A Saunders, Janice Drew, Claus Mayer, Heather Brookes, Nick J Gay, Emad M El-Omar, Clare E Bryant
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111460 (2014)
Dysregulated Toll-Like Receptor (TLR) signalling and genetic polymorphisms in these proteins are linked to many human diseases. We investigated TLR4 functional variants D299G and T399I to assess the impact on LPS-induced responsiveness in comparison
Externí odkaz:
https://doaj.org/article/00f6564b2db24b8cae4420cc91841f22
Autor:
Richard Hansen, Susan H Berry, Indrani Mukhopadhya, John M Thomson, Karin A Saunders, Charlotte E Nicholl, W Michael Bisset, Sabarinathan Loganathan, Gamal Mahdi, Dagmar Kastner-Cole, Andy R Barclay, Jon Bishop, Diana M Flynn, Paraic McGrogan, Richard K Russell, Emad M El-Omar, Georgina L Hold
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58825 (2013)
Children presenting for the first time with inflammatory bowel disease (IBD) offer a unique opportunity to study aetiological agents before the confounders of treatment. Microaerophilic bacteria can exploit the ecological niche of the intestinal epit
Externí odkaz:
https://doaj.org/article/252176b8bfb34a519587f8ca47fbbe73
Autor:
Lisa Cuiying Ho, Umi Nursheila Nur Ibrahim, Karin A. Saunders, Sohinee Bhattacharya, Deborah Jane Owen
Publikováno v:
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 2:341-349
Introduction Pre-eclampsia, defined as the development of hypertension and proteinuria after 20weeks gestation, carries significant maternal and foetal risk. Pre-pregnancy BMI is the most useful predictor of pre-eclampsia. As the prevalence of obesit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77145fffe66f360f94f6041d821c5992
https://doi.org/10.1016/j.preghy.2012.03.003
https://doi.org/10.1016/j.preghy.2012.03.003
Autor:
W. Michael Bisset, Charlotte E. Nicholl, Paraic McGrogan, A. R. Barclay, Diana M. Flynn, J. Bishop, Emad M. El-Omar, Richard Hansen, S Loganathan, Karin A. Saunders, Indrani Mukhopadhya, Gamal Mahdi, Dagmar Kastner-Cole, John M. Thomson, Georgina L. Hold, Richard K Russell, Susan H. Berry
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58825 (2013)
PLoS ONE
PLoS ONE
Introduction Children presenting for the first time with inflammatory bowel disease (IBD) offer a unique opportunity to study aetiological agents before the confounders of treatment. Microaerophilic bacteria can exploit the ecological niche of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00e857f6d0803fc29da2c440f3b91ab
http://europepmc.org/articles/PMC3595230?pdf=render
http://europepmc.org/articles/PMC3595230?pdf=render
Publikováno v:
Fibrogenesis & Tissue Repair
Fibrosis can occur in tissues in response to a variety of stimuli. Following tissue injury, cells undergo transformation or activation from a quiescent to an activated state resulting in tissue remodelling. The fibrogenic process creates a tissue env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4088247d212701acb9eb7024bd5b524d
https://doi.org/10.1186/1755-1536-2-6
https://doi.org/10.1186/1755-1536-2-6
Autor:
James Alexander, Frank Brombracher, Chesney E. Michels, S. McGowan, Catherine E. Lawrence, Hannah E. Scales, Karin A. Saunders
Publikováno v:
Immunology. 128
The T helper type 2 (Th2) mediated expulsion of the gastrointestinal nematode Trichinella spiralis requires interleukin-4 receptor alpha (IL-4Ralpha) expression on both bone-marrow-derived and non-bone-marrow-derived cells. To more definitively inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9066a132ed44989f6a98300bf9bca0b9
https://pubmed.ncbi.nlm.nih.gov/19191917
https://pubmed.ncbi.nlm.nih.gov/19191917
Gastrointestinal nematode infections are prevalent worldwide and are potent inducers of T helper 2 responses with the capacity to modulate the immune response to heterologous antigens. Parasitic helminth infection has even been shown to modulate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f94ee0b9727114c44f83595fd8c0dd8
https://europepmc.org/articles/PMC1828378/
https://europepmc.org/articles/PMC1828378/
Autor:
Charlotte E. Nicholl, Richard K Russell, Karin A. Saunders, Georgina L. Hold, Susan H. Berry, John M. Thomson, Emad M. El-Omar, M Bisset, Richard Hansen, Indrani Mukhopadhya
Publikováno v:
Gut. 62:A31.1-A31
Introduction Children presenting for the first time with inflammatory bowel disease (IBD) offer a unique opportunity to study etiological agents before the confounders of treatment. Microaerophilic bacteria can exploit the ecological niche of the int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f3bd7f84f1a4e652a47462c28345c65
https://doi.org/10.1136/gutjnl-2013-304907.071
https://doi.org/10.1136/gutjnl-2013-304907.071
Publikováno v:
Gastroenterology. 138:S-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bce034f39a0a83849be8466d66b8a92
https://doi.org/10.1016/s0016-5085(10)61111-0
https://doi.org/10.1016/s0016-5085(10)61111-0
Publikováno v:
Gut. 59:A20.1-A20
Introduction The TLR4 Asp299Gly polymorphism causes immune dysregulation and is associated with unfavourable outcome in H pylori induced gastric cancer. It has been suggested that the polymorphism exerts effects through post-receptor signalling, more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd0aabf96d10323444efa438fa87924
https://doi.org/10.1136/gut.2009.208959v
https://doi.org/10.1136/gut.2009.208959v