Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Karin Milde-Langosch"'
Autor:
Sandra Genduso, Vera Freytag, Daniela Schetler, Lennart Kirchner, Alina Schiecke, Hanna Maar, Daniel Wicklein, Florian Gebauer, Katharina Bröker, Christine Stürken, Karin Milde-Langosch, Leticia Oliveira-Ferrer, Franz L. Ricklefs, Florian Ewald, Gerrit Wolters-Eisfeld, Kristoffer Riecken, Ludmilla Unrau, Linda Krause, Hanibal Bohnenberger, Anne Offermann, Sven Perner, Susanne Sebens, Katrin Lamszus, Linda Diehl, Stefan Linder, Manfred Jücker, Udo Schumacher, Tobias Lange
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-24 (2023)
Abstract Background The immunological composition of the tumor microenvironment has a decisive influence on the biological course of cancer and is therefore of profound clinical relevance. In this study, we analyzed the cooperative effects of integri
Externí odkaz:
https://doaj.org/article/15a2e60098c04388b2f1c864ee3b2031
Autor:
Francesca Reimer, Sarah Bryan, Karen Legler, Thomas Karn, Serenella Eppenberger-Castori, Jakob Matschke, Thais Pereira-Veiga, Harriet Wikman, Isabell Witzel, Volkmar Müller, Barbara Schmalfeldt, Karin Milde-Langosch, Udo Schumacher, Christine Stürken, Leticia Oliveira-Ferrer
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background The disruption of epithelial features represents a critical step during breast cancer spread. In this context, the dysregulation of desmosomal proteins has been associated with malignant progression and metastasis formation. Curio
Externí odkaz:
https://doaj.org/article/7dd783cb52b64e1398cec4d6e4826b38
Autor:
Christine Stürken, Volker Möbus, Karin Milde-Langosch, Sabine Schmatloch, Peter A. Fasching, Josef Rüschoff, Elmar Stickeler, Rolf-Peter Henke, Carsten Denkert, Lars Hanker, Christian Schem, Valentina Vladimirova, Thomas Karn, Valentina Nekljudova, Claus-Henning Köhne, Frederik Marmé, Udo Schumacher, Sibylle Loibl, Volkmar Müller
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Breast cancer (BC) is the most frequent female cancer and preferentially metastasizes to bone. The transcription factor TGFB-induced factor homeobox 1 (TGIF) is involved in bone metabolism. However, it is not yet known whether TGI
Externí odkaz:
https://doaj.org/article/c69ff00bda2f4529a85614e57c4f1988
Autor:
Yi Ding, Leticia Oliveira-Ferrer, Eike Vettorazzi, Karen Legler, Karin Milde-Langosch, Linn Woelber, Anna Jaeger, Katharina Prieske, Volkmar Mueller, Barbara Schmalfeldt, Sascha Kuerti
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269680 (2022)
ObjectiveAt present, maintenance therapy with the antiangiogenic agent bevacizumab or with PARP-inhibitors represent two options for BRCA-wildtype ovarian cancer patients, after platinum-based first line chemotherapy. The identification of molecular
Externí odkaz:
https://doaj.org/article/38c4f26db8f94b77be5d55892a2c84ad
Autor:
Malgorzata Banys-Paluchowski, Tanja Fehm, Wolfgang Janni, Bahriye Aktas, Peter A. Fasching, Sabine Kasimir-Bauer, Karin Milde-Langosch, Klaus Pantel, Brigitte Rack, Sabine Riethdorf, Erich-Franz Solomayer, Isabell Witzel, Volkmar Müller
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background An important component of the RAS signalling pathway, the RAS p21 oncogene, is frequently hyperactivated in breast cancer. Its expression in tumor tissue has been linked to poor clinical outcome. This study was designed to evaluat
Externí odkaz:
https://doaj.org/article/2fa49fc6eb53443b9cefb3416ca47836
Autor:
Christine Stürken, Volker Möbus, Karin Milde-Langosch, Sabine Schmatloch, Peter A. Fasching, Josef Rüschoff, Elmar Stickeler, Rolf-Peter Henke, Carsten Denkert, Lars Hanker, Christian Schem, Valentina Vladimirova, Thomas Karn, Valentina Nekljudova, Claus-Henning Köhne, Frederik Marmé, Udo Schumacher, Sibylle Loibl, Volkmar Müller
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/c9d26cf8ebe64f5d8bb80d323fe092e0
Autor:
Stepan Nersisyan, Sabrina Arnold, Alexander G. Tonevitsky, Christine Stürken, Susanne Lezius, Udo Schumacher, Timur R. Samatov, D. V. Maltseva, Jan Kortland, Daniel Wicklein, Karin Milde-Langosch
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:1525-1542
PurposeThe transcription factor Fra-2 affects the invasive potential of breast cancer cells by dysregulating adhesion molecules in vitro. Previous results suggested that it upregulates the expression of E- and P-selectin ligands. Such selectin ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09586e4f8cdc28cb9fc76b952300f8c7
https://doi.org/10.1007/s00432-021-03812-2
https://doi.org/10.1007/s00432-021-03812-2
Autor:
Yi Ding, Leticia Oliveira-Ferrer, Eike Vettorazzi, Karen Legler, Karin Milde-Langosch, Linn Woelber, Anna Jaeger, Katharina Prieske, Volkmar Mueller, Barbara Schmalfeldt, Sascha Kuerti
Publikováno v:
PloS one. 17(6)
Objective At present, maintenance therapy with the antiangiogenic agent bevacizumab or with PARP-inhibitors represent two options for BRCA-wildtype ovarian cancer patients, after platinum-based first line chemotherapy. The identification of molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faa38a5535a007dc8dfbd189537bfd4
https://pubmed.ncbi.nlm.nih.gov/35687576
https://pubmed.ncbi.nlm.nih.gov/35687576
Autor:
Fabienne Hamester, Karin Milde-Langosch, Barbara Schmalfeldt, Yi Ding, Kathrin Eylmann, Beatrice Wichert, Nicole Kelle, Maila Rossberg, Leticia Oliveira-Ferrer, Sascha Kürti, Karen Legler
Publikováno v:
British Journal of Cancer
BackgroundMaturation of complex N-glycans involves the action of Golgi mannosidases and plays a major role in cancer progression. We recently showed a favourable prognostic role of α-mannosidase MAN1A1 in breast cancer mainly caused by alteration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4414db1aa08c4d0a17ae0c83fcf7e6
https://doi.org/10.1038/s41416-019-0607-2
https://doi.org/10.1038/s41416-019-0607-2
Autor:
Leticia Oliveira-Ferrer, Tanja Fehm, Volkmar Müller, Karin Milde-Langosch, Isabell Witzel, Malgorzata Banys-Paluchowski, Barbara Schmalfeldt
Publikováno v:
Breast Cancer Research and Treatment. 179:403-414
The RAS family comprises three proto-oncogenes (H-RAS, K-RAS, and N-RAS) and is among the most widely studied of oncogenes. The present study aimed at investigating the clinical relevance of mRNA levels of the three isoforms in a large group of breas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45850a5da343ccb86ace578b817baed
https://doi.org/10.1007/s10549-019-05474-8
https://doi.org/10.1007/s10549-019-05474-8