Single-Shot Vaccines against Bovine Respiratory Syncytial Virus (BRSV): Comparative Evaluation of Long-Term Protection after Immunization in the Presence of BRSV-Specific Maternal Antibodies

Autor: Jean François Valarcher, Sara Hägglund, Katarina Näslund, Luc Jouneau, Ester Malmström, Olivier Boulesteix, Anne Pinard, Dany Leguéré, Alain Deslis, David Gauthier, Catherine Dubuquoy, Vincent Pietralunga, Aude Rémot, Alexander Falk, Ganna Shevchenko, Sara Bergström Lind, Claudia Von Brömssen, Karin Vargmar, Baoshan Zhang, Peter D. Kwong, María Jose Rodriguez, Marga Garcia Duran, Isabelle Schwartz-Cornil, Geraldine Taylor, Sabine Riffault

Publikováno v: Vaccines, Vol 9, Iss 3, p 236 (2021)

The induction of long-lasting clinical and virological protection is needed for a successful vaccination program against the bovine respiratory syncytial virus (BRSV). In this study, calves with BRSV-specific maternally derived antibodies were vaccin

Externí odkaz: https://doaj.org/article/14e8581d0527445b8ffbe4eb17e80d8b

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus-Insights in pathogenesis and perspectives for new treatments.

Autor: Sara Hägglund, Krister Blodörn, Katarina Näslund, Karin Vargmar, Sara Bergström Lind, Jia Mi, Mariluz Araínga, Sabine Riffault, Geraldine Taylor, John Pringle, Jean François Valarcher

Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0186594 (2017)

Human and bovine respiratory syncytial viruses (HRSV/BRSV) are major causes of severe lower respiratory tract infections in children and calves, respectively. Shared epidemiological, clinical, pathological and genetic characteristics of these viruses

Externí odkaz: https://doaj.org/article/22be47e218f643e1bfc8b44a3cae00b0

A Single Shot Pre-fusion-Stabilized Bovine RSV F Vaccine is Safe and Effective in Newborn Calves with Maternally Derived Antibodies

Autor: David Gauthier, Peter D. Kwong, Karin Vargmar, Sara Bergström Lind, Sara Hägglund, Alexander Falk, Geraldine Taylor, Efrain Guzman, Baoshan Zhang, Sabine Riffault, Luc Jouneau, Daphné Laubreton, Jean-François Eléouët, Jean-Francois Valarcher, Aude Remot, Ganna Shevchenko, Vincent Pietralunga, Marga Garcia Duran, Catherine Dubuquoy, Olivier Boulesteix, María Jose Rodriguez, Abdelhak Boukaridi, Isabelle Schwartz-Cornil, Katarina Näslund

Publikováno v: Vaccines
Volume 8
Issue 2
Vaccines, Vol 8, Iss 231, p 231 (2020)
Vaccines, MDPI, 2020, 8 (2), 21 p. ⟨10.3390/vaccines8020231⟩
Vaccines, 2020, 8 (2), 21 p. ⟨10.3390/vaccines8020231⟩

International audience; Achieving safe and protective vaccination against respiratory syncytial virus (RSV) in infants and in calves has proven a challenging task. The design of recombinant antigens with a conformation close to their native form in v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275af0c794b87ae916185f24ebb787c8

Bovine respiratory syncytial virus ISCOMs—Immunity, protection and safety in young conventional calves

Autor: Geraldine Taylor, Sara Hägglund, John Pringle, Kefei Hu, Krister Blodörn, Parvin Ahooghalandari, Karin Vargmar, Ann-Sophie Olofson, Jenna Anderson, Jean-Francois Valarcher, Lesly Poré

Publikováno v: Vaccine

Highlights ► BRSV-ISCOMs induce strong clinical and virological protection in young conventional calves with BRSV-specific maternal antibodies. ► Protection is associated with local and systemic humoral responses as well as T cell responses domin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa47d1dfbf262b36baa7f8a7d8091fa3
https://doi.org/10.1016/j.vaccine.2011.07.146