Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karin, Rustler"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 780-788 (2019)
The serotonin 5-hydroxytryptamine 3 receptor (5-HT3R) plays a unique role within the seven classes of the serotonin receptor family, as it represents the only ionotropic receptor, while the other six members are G protein-coupled receptors (GPCRs). T
Externí odkaz:
https://doaj.org/article/cc476cf96b6a41858df50851f3b562f1
Publikováno v:
Organic Process Research & Development. 26:144-148
Autor:
Srinivasa Rao Manne, Karin Rustler, Thomas Bruckdorfer, Beatriz G. de la Torre, Fernando Albericio
Publikováno v:
Tetrahedron Letters. 115:154301
Publikováno v:
ChemMedChem. 14:636-644
The histamine H1 G protein-coupled receptor (GPCR) plays an important role in allergy and inflammation. Existing drugs that address the H1 receptor differ in their chemical structure, pharmacology, and side effects. Light-controllable spatial and tem
Autor:
Piotr Bregestovski, Daniel Wutz, Mercedes Alfonso-Prieto, Alexandre M. J. Gomila, Elena Petukhova, Daria Ponomareva, Alba Nin-Hill, Elvira Mukhametova, Galyna Maleeva, Burkhard König, Pau Gorostiza, Karin Rustler
Publikováno v:
Juelich Shared Electronic Resources
Recolector de Ciencia Abierta, RECOLECTA
PubMed Central
Diposit Digital de la Universitat de Barcelona
ZENODO
UnpayWall
ORCID
Microsoft Academic Graph
eNeuro
eNeuro 8(1), ENEURO.0294-20.2020 (2021). doi:10.1523/ENEURO.0294-20.2020
Dipòsit Digital de la UB
Universidad de Barcelona
Recolector de Ciencia Abierta, RECOLECTA
PubMed Central
Diposit Digital de la Universitat de Barcelona
ZENODO
UnpayWall
ORCID
Microsoft Academic Graph
eNeuro
eNeuro 8(1), ENEURO.0294-20.2020 (2021). doi:10.1523/ENEURO.0294-20.2020
Dipòsit Digital de la UB
Universidad de Barcelona
Visual Abstract
Photopharmacology is a unique approach that through a combination of photochemistry methods and advanced life science techniques allows the study and control of specific biological processes, ranging from intracellular pathways t
Photopharmacology is a unique approach that through a combination of photochemistry methods and advanced life science techniques allows the study and control of specific biological processes, ranging from intracellular pathways t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85157fce2e1f37520dd1f809189e5c0b
http://europepmc.org/articles/PMC7877471
http://europepmc.org/articles/PMC7877471
Autor:
Elvira Mukhametova, Alba Nin-Hill, Franck Peiretti, Burkhard König, Daniel Wutz, Piotr Bregestovski, Marat A. Mukhamedyarov, Xavier Rovira, Miquel Bosch, Daria Ponomareva, Carme Rovira, Pau Gorostiza, Karin Rustler, Galyna Maleeva, Antoni Bautista-Barrufet, Alexandre M. J. Gomila, Elena Petukhova, Mercedes Alfonso-Prieto
Publikováno v:
Cell Chemical Biology
Cell Chemical Biology, Cell Press, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell Chemical Biology, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell chemical biology 27(11), 1425-1433.e7 (2020). doi:10.1016/j.chembiol.2020.08.005
Cell Chemical Biology, Cell Press, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell Chemical Biology, 2020, 27 (11), pp.1425-1433.e7. ⟨10.1016/j.chembiol.2020.08.005⟩
Cell chemical biology 27(11), 1425-1433.e7 (2020). doi:10.1016/j.chembiol.2020.08.005
International audience; Glycine receptors (GlyRs) are indispensable for maintaining excitatory/inhibitory balance in neuronal circuits that control reflexes and rhythmic motor behaviors. Here we have developed Glyght, a GlyR ligand controlled with li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed65a1a37c5f8c8a059ac5ec10c4b995
https://www.hal.inserm.fr/inserm-03032018/document
https://www.hal.inserm.fr/inserm-03032018/document
Autor:
Sophie Zahnbrecher, Philipp Nitschke, Karin Rustler, Burkhard König, Stefano Crespi, Julia Zach
Publikováno v:
Journal of Organic Chemistry, 85(6), 4079-4088. AMER CHEMICAL SOC INC
The desire to photocontrol molecular properties ranging from materials to pharmacology using light as an external trigger with high spatiotemporal resolution led to the development of a broad range of photochromic scaffolds. Among them, azobenzenes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e381d04aa60a606fdd889a9bbe6c3fd
https://research.rug.nl/en/publications/4aa0b432-ef9d-4b6f-abc0-19e3546d7a2e
https://research.rug.nl/en/publications/4aa0b432-ef9d-4b6f-abc0-19e3546d7a2e
Autor:
Karin, Rustler, Philipp, Nitschke, Sophie, Zahnbrecher, Julia, Zach, Stefano, Crespi, Burkhard, König
Publikováno v:
The Journal of organic chemistry. 85(6)
The desire to photocontrol molecular properties ranging from materials to pharmacology using light as an external trigger with high spatiotemporal resolution led to the development of a broad range of photochromic scaffolds. Among them, azobenzenes a
Autor:
Karin, Rustler, Galyna, Maleeva, Alexandre M J, Gomila, Pau, Gorostiza, Piotr, Bregestovski, Burkhard, König
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Optogenetic and photopharmacological tools to manipulate neuronal inhibition have limited efficacy and reversibility. We report the design, synthesis, and biological evaluation of Fulgazepam, a fulgimide derivative of benzodiazepine that behaves as a
Autor:
Burkhard König, Rainer Merkl, Hans H. Gorris, Julian Nazet, Matthias Jürgen Mickert, Karin Rustler
Publikováno v:
Organic & Biomolecular Chemistry. 16:7430-7437
Azobenzenes are of particular interest as a photochromic scaffold for biological applications because of their high fatigue resistance, their large geometrical change between extended (trans) and bent (cis) isomer, and their diverse synthetic accessi