Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Karin, Kovar"'
Autor:
Hana Raschmanová, Iwo Zamora, Martina Borčinová, Patrick Meier, Astrid Weninger, Dominik Mächler, Anton Glieder, Karel Melzoch, Zdeněk Knejzlík, Karin Kovar
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Pichia pastoris (Komagataella sp.) is broadly used for the production of secreted recombinant proteins. Due to the high rate of protein production, incorrectly folded proteins may accumulate in the endoplasmic reticulum (ER). To restore their proper
Externí odkaz:
https://doaj.org/article/289591b63495445b82e537f21870a2e8
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Folding and processing of proteins in the endoplasmic reticulum (ER) are major impediments in the production and secretion of proteins from Pichia pastoris (Komagataella sp.). Overexpression of recombinant genes can overwhelm the innate secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bfea256137ea647da683ea11304b6f
https://doi.org/10.1007/s00253-021-11336-5
https://doi.org/10.1007/s00253-021-11336-5
Publikováno v:
Biotechnology Advances. 58:107917
Chimeric antigen receptor (CAR) technology, and CAR-T cells in particular, have emerged as a new and powerful tool in cancer immunotherapy since demonstrating efficacy against several hematological malignancies. However, despite encouraging clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586ab6bf23b541a5f026428326b6d16d
https://doi.org/10.1016/j.biotechadv.2022.107917
https://doi.org/10.1016/j.biotechadv.2022.107917
Autor:
Marcel Meury, Meritxell Costa, Daniel Harder, Mirko Stauffer, Jean-Marc Jeckelmann, Béla Brühlmann, Albert Rosell, Hüseyin Ilgü, Karin Kovar, Manuel Palacín, Dimitrios Fotiadis
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109882 (2014)
Human heteromeric amino acid transporters (HATs) are membrane protein complexes that facilitate the transport of specific amino acids across cell membranes. Loss of function or overexpression of these transporters is implicated in several human disea
Externí odkaz:
https://doaj.org/article/3af0eb8263c64a2390ae8de7d24b3e85
Autor:
Iwo Zamora, Helena Marešová, Verena Looser, Martina Borčinová, Karin Kovar, Hana Raschmanová, Sven Hirsch, Pavel Kyslík
Publikováno v:
Applied Microbiology and Biotechnology
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)
To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory proce
To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9378c7a5774a056595b574164e7073
Autor:
Zdeněk Knejzlík, Hana Raschmanová, Karel Melzoch, Leona Paulova, Karin Kovar, Barbora Branska
Publikováno v:
Folia Microbiologica. 63:773-787
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) Pharmaceutical grade trypsin is in ever-increasing demand for medical and industrial applications. Improving the efficiency of existing biotechnological manufacturing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0eed1d5c0e3d4e32c6c58f30d00366a
https://doi.org/10.1007/s12223-018-0619-y
https://doi.org/10.1007/s12223-018-0619-y
Publikováno v:
CHIMIA, Vol 64, Iss 11 (2010)
Health and safety concerns, enhanced quality criteria, and environmental sustainability, have prompted investigations into production using recombinant yeasts as a feasible alternative for isolation of proteins from natural animal or plant sources, a
Externí odkaz:
https://doaj.org/article/a8a910bb1b874057af67b408d4a96250
Publikováno v:
CHIMIA, Vol 61, Iss 9 (2007)
The Institute of Biotechnology (formerly the Department of Biotechnology) at the Zurich University of Applied Sciences in Wädenswil has established itself internationally. Building-up expertise in complementary research fields as well as an orientat
Externí odkaz:
https://doaj.org/article/9568db2748b043f9b5da17438fed3ec0
Autor:
Karin Kovar, Thomas K. Friedli, Dusan Roubicek, David S. Langenegger, Markus Keller, Hans-Peter Meyer
Publikováno v:
CHIMIA, Vol 59, Iss 10 (2005)
Huge amounts of data are routinely logged and stored during the monitoring of biotechnological production processes. A concept is described to extract and analyse the information these data contain and to subsequently apply it for process improvement
Externí odkaz:
https://doaj.org/article/b1b2d8a36ce442f2be0960e4aef93a6f
Autor:
Karin Kovar, Hans-Peter Meyer
Publikováno v:
CHIMIA, Vol 59, Iss 10 (2005)
Externí odkaz:
https://doaj.org/article/e434a323251f4f95a698fb7a322b1306