Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Karima Habbout"'
Autor:
Sandra Breuils-Bonnet, Allan Lawrie, Stephen L. Archer, Eve Tremblay, Tsukasa Shimauchi, François Potus, David G. Kiely, Wen-Hui Wu, Jianhui Lin, Olivier Boucherat, Valérie Nadeau, Sébastien Bonnet, Kassandra Gagnon, Sandra Martineau, Karima Habbout, Hamza Zafar, Roxane Paulin, Steeve Provencher, Junichi Omura, Jean Perron, Florence Mazoyer
Publikováno v:
Circulation. 142:1464-1484
Background: Right ventricular (RV) function is the major determinant for both functional capacity and survival in patients with pulmonary arterial hypertension (PAH). Despite the recognized clinical importance of preserving RV function, the subcellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e40c0755eff6d2f6718ab7a141e5da3
https://doi.org/10.1161/circulationaha.120.047626
https://doi.org/10.1161/circulationaha.120.047626
Autor:
Olivier Boucherat, Charifa Awada, Sébastien Bonnet, Roxane Paulin, Sandra Breuils-Bonnet, Karima Habbout, Steeve Provencher, Valérie Nadeau
Publikováno v:
Circulation. 142
Rationale: Pulmonary arterial hypertension (PAH) is a cardiopulmonary disorder characterized by elevation of pulmonary arterial (PA) pressure and premature death. PA smooth muscle cells (PASMCs) from PAH patients present a cancer-like hyperproliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fee418086734b131ce7aeee08cee68fb
https://doi.org/10.1161/circ.142.suppl_3.15544
https://doi.org/10.1161/circ.142.suppl_3.15544
Autor:
Sarah-Eve Lemay, Roxane Paulin, Alice Bourgeois, Eve Tremblay, Renée Paradis, Geraldine Vitry, Karima Habbout, Marie-Claude Lampron, Olivier Boucherat, Sandra Breuils-Bonnet, Florence Roux-Dalvai, Yann Grobs, Charifa Awada, Tsukasa Shimauchi, Mark Orcholski, Valérie Nadeau, Steeve Provencher, François Potus, Sébastien Bonnet
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by abnormally elevated pulmonary pressures and right ventricular failure. Excessive proliferation and resistance to apoptosis of pulmonary artery smooth mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30618c1c0a8f8c41797ea0089406445b
https://pubmed.ncbi.nlm.nih.gov/33095993
https://pubmed.ncbi.nlm.nih.gov/33095993
Autor:
Yann Grobs, Olivier Boucherat, Sandra Breuils-Bonnet, Steeve Provencher, François Potus, Charlotte Romanet, Charifa Awada, Sandra Martineau, Wen-Hui Wu, Eve Tremblay, Karima Habbout, Sébastien Bonnet, Roxane Paulin
Publikováno v:
The European respiratory journal. 57(5)
Pulmonary hypertension (PH) is a life-threatening disease of multiple etiologies. Regardless of the underlying cause, PH is characterised by vasoconstriction and progressive thickening of the pulmonary vessel wall all of which is initiated by the los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28cc1914696b1b0309b67dba800cf4a4
https://pubmed.ncbi.nlm.nih.gov/33446610
https://pubmed.ncbi.nlm.nih.gov/33446610
Autor:
Olivier Boucherat, S. Provencher, Roxanne Paulin, Valérie Nadeau, Sandra Breuils Bonnet, Charifa Awada, Karima Habbout, S. Breuils Bonnet
Publikováno v:
D25. O BRAVE NEW WORLD! OMICS, SYSTEM BIOLOGY, AND NEW MOLECULAR MECHANISMS OF PULMONARY HYPERTENSION.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50660b6f413b145a58783ed05000759c
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6361
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6361
Autor:
François Potus, Sandra Martineau, Junichi Omura, Sandra Breuils-Bonnet, S. Provencher, Valérie Nadeau, Karima Habbout, Eve Tremblay, Hamza Zafar, Sandra Breuils Bonnet, Allan Lawrie, Jianhui Lin, Olivier Boucherat, Stephen L. Archer, Tsukasa Shimauchi, Roxane Paulin, David G. Kiely
Publikováno v:
C105. WITH ALL MY HEART: SEX, ESTROGEN, AND RIGHT VENTRICLE IN PULMONARY VASCULAR DISEASE AND BEYOND.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c7eb4d0d6d7f62ab6de0da6f5291996
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6076
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6076
Autor:
Sandra Breuils Bonnet, Karima Habbout, François Potus, Roxane Paulin, Stephen L. Archer, Sandra Martineau, Sandra Breuils-Bonnet, Jianhui Lin, Olivier Boucherat, Eve Tremblay, Allan Lawrie, Valérie Nadeau, David G. Kiely, Junichi Omura, S. Provencher, Tsukasa Shimauchi, Hamza Zafar
Publikováno v:
A93. TRANSLATIONAL RESEARCH; EARLY CLINICAL FINDINGS AND OMICS ADVENTURE IN PULMONARY HYPERTENSION: FROM BIOMARKERS TO NEW THERAPEUTIC TARGETS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c410092f010b56a8adc6b8b0ecd221e3
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2496
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2496
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 104:9-13
Pulmonary arterial hypertension (PAH) encompasses a group of clinical entities characterized by sustained vasoconstriction and progressive vascular remodeling that act in concert to elevate pulmonary vascular resistance. The current treatments for PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba6eeff4ffbf11364b5526830f1ac9d
https://doi.org/10.1016/j.biocel.2018.08.015
https://doi.org/10.1016/j.biocel.2018.08.015
Autor:
Saïd Bendahhou, Pascal Gosselin-Badaroudine, Serena Giuliano, Savine Vicart, Mohamed Chahine, Hugo Poulin, Sophie Nicole, Damien Sternberg, Karima Habbout, Bertrand Fontaine
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8, pp.2041. ⟨10.1038/s41598-018-20468-0⟩
Scientific Reports, 2018, 8, pp.2041. ⟨10.1038/s41598-018-20468-0⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8, pp.2041. ⟨10.1038/s41598-018-20468-0⟩
Scientific Reports, 2018, 8, pp.2041. ⟨10.1038/s41598-018-20468-0⟩
Mutations in NaV1.4, the skeletal muscle voltage-gated Na+ channel, underlie several skeletal muscle channelopathies. We report here the functional characterization of two substitutions targeting the R1451 residue and resulting in 3 distinct clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef7279d6e17036666d272fb8a3e31a0
http://link.springer.com/article/10.1038/s41598-018-20468-0
http://link.springer.com/article/10.1038/s41598-018-20468-0
Autor:
Benoit Ranchoux, Sandra Breuils-Bonnet, Valérie Nadeau, Renée Paradis, Alice Bourgeois, Roxane Paulin, Olivier Boucherat, Karima Habbout, Sébastien Bonnet, Caroline Lambert, Stéphanie Paquet-Marceau, Steeve Provencher, Isabelle Trinh
Publikováno v:
Journal of Molecular Medicine. 96:223-235
Pulmonary arterial hypertension (PAH) is a progressive vascular remodeling disease characterized by a persistent elevation of pulmonary artery pressure, leading to right heart failure and premature death. Exaggerated proliferation and resistance to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c4941973faa55952a69c6545b8633b
https://doi.org/10.1007/s00109-017-1619-0
https://doi.org/10.1007/s00109-017-1619-0