Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karima Drareni"'
Autor:
Elizabeth Nunn, Natasha Jaiswal, Matthew Gavin, Kahealani Uehara, Megan Stefkovich, Karima Drareni, Ryan Calhoun, Michelle Lee, Corey D. Holman, Joseph A. Baur, Patrick Seale, Paul M. Titchenell
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101880- (2024)
Objective: Glucagon-like peptide 1 (GLP-1) receptor agonists reduce food intake, producing remarkable weight loss in overweight and obese individuals. While much of this weight loss is fat mass, there is also a loss of lean mass, similar to other app
Externí odkaz:
https://doaj.org/article/3c25c8696bac45cc8a33929b89a5909f
Autor:
Blandine Secco, Kevin Saitoski, Karima Drareni, Antoine Soprani, Severine Pechberty, Latif Rachdi, Nicolas Venteclef, Raphaël Scharfmann
Publikováno v:
Cells, Vol 11, Iss 6, p 924 (2022)
In human type 2 diabetes, adipose tissue plays an important role in disturbing glucose homeostasis by secreting factors that affect the function of cells and tissues throughout the body, including insulin-producing pancreatic beta cells. We aimed her
Externí odkaz:
https://doaj.org/article/2ec744c61c474f6dbf1050ec6e03cf0e
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Type-2 diabetes (T2D) is a disease of two etiologies: metabolic and inflammatory. At the cross-section of these etiologies lays the phenomenon of metabolic inflammation. Whilst metabolic inflammation is characterized as systemic, a common starting po
Externí odkaz:
https://doaj.org/article/8cab762be24b48a8a6c0cddeab5e9730
Autor:
Karima Drareni, Raphaëlle Ballaire, Serena Barilla, Mano J. Mathew, Amine Toubal, Rongrong Fan, Ning Liang, Catherine Chollet, Zhiqiang Huang, Maria Kondili, Fabienne Foufelle, Antoine Soprani, Ronan Roussel, Jean-François Gautier, Fawaz Alzaid, Eckardt Treuter, Nicolas Venteclef
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 2957-2971.e6 (2018)
Summary: Hypertrophic white adipose tissue (WAT) represents a maladaptive mechanism linked to the risk for developing type 2 diabetes in humans. However, the molecular events that predispose WAT to hypertrophy are poorly defined. Here, we demonstrate
Externí odkaz:
https://doaj.org/article/326c110314a9499289414635556a19cd
Autor:
J.-L. Nguewa, Jean-François Gautier, Gilberto Velho, Ronan Roussel, Jean-Pierre Riveline, Karima Drareni, Nicolas Venteclef
Publikováno v:
Diabetes. 69
The transcriptional corepressor GPS2 plays a key role in human adipose tissue homeostasis. Decreased expression of GPS2 in adipocytes was associated with increased expression of inflammatory genes and with a pro-diabetic status. Here we assessed asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9641c30c1b7c3957e1dfd8912b4b172a
https://doi.org/10.2337/db20-1799-p
https://doi.org/10.2337/db20-1799-p
Autor:
Rongrong Fan, Toby Lawrence, Judith Aron-Wisnewsky, Fabienne Foufelle, Zhiqiang Huang, Patricia Ancel, Anastasios E. Damdimopoulos, Antoine Soprani, Isabelle Hainault, Ning Liang, Saioa Goñi, Raphaelle Ballaire, Jean-François Gautier, Amine Toubal, Karima Drareni, Fawaz Alzaid, Eckardt Treuter, Nicolas Venteclef
Publikováno v:
Nature Medicine
Nature Medicine, 2016, 22 (7), pp.780-791. ⟨10.1038/nm.4114⟩
Nature Medicine, Nature Publishing Group, 2016, 22 (7), pp.780-791. ⟨10.1038/nm.4114⟩
Nature Medicine, 2016, 22 (7), pp.780-791. ⟨10.1038/nm.4114⟩
Nature Medicine, Nature Publishing Group, 2016, 22 (7), pp.780-791. ⟨10.1038/nm.4114⟩
International audience; Humans with obesity differ in their susceptibility to developing insulin resistance and type 2 diabetes (T2D). This variation may relate to the extent of adipose tissue (AT) inflammation that develops as their obesity progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1fae84484ad3da68e69f3aa0019635
https://hal.science/hal-01438151
https://hal.science/hal-01438151
Autor:
Serena Barilla, Nicolas Venteclef, Fabienne Foufelle, Eckardt Treuter, Karima Drareni, Raphaelle Ballaire, Amine Toubal, Fawaz Al azaid
Publikováno v:
Diabetes & Metabolism. 43:A34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d22601f1ecd6f9975c0395b17188a43
https://doi.org/10.1016/s1262-3636(17)30202-1
https://doi.org/10.1016/s1262-3636(17)30202-1
Publikováno v:
Seminars in Immunopathology
Type-2 diabetes (T2D) is considered today as an inflammatory disease. Inflammatory processes in T2D are orchestrated by macrophage activation in different organs. Macrophages undergo classical M1 pro-inflammatory or alternative M2 anti-inflammatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e973fee9a70ffdcffb007311816c9879