Výsledky vyhledávání - "Karima Brahimi"

Akademický článek

Monoclonal auto-antibodies and sera of autoimmune patients react with Plasmodium falciparum and inhibit its in vitro growth

Autor: Karima Brahimi, Yuri Chaves Martins, Graziela Maria Zanini, Maria de Fátima Ferreira-da-Cruz, Cláudio Tadeu Daniel-Ribeiro

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 106, Iss suppl 1, Pp 44-51 (2011)

The relationship between autoimmunity and malaria is not well understood. To determine whether autoimmune responses have a protective role during malaria, we studied the pattern of reactivity to plasmodial antigens of sera from 93 patients with 14 di

Externí odkaz: https://doaj.org/article/5fbe682b9689437c8bc20d66af0a00f8

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Akademický článek

Genetic immunisation by liver stage antigen 3 protects chimpanzees against malaria despite low immune responses.

Autor: Pierre Daubersies, Benjamin Ollomo, Jean-Pierre Sauzet, Karima Brahimi, Blanca-Liliana Perlaza, Wijnand Eling, Hubert Moukana, Pierre Rouquet, Charles de Taisne, Pierre Druilhe

Publikováno v: PLoS ONE, Vol 3, Iss 7, p e2659 (2008)

BACKGROUND: The true interest of genetic immunisation might have been hastily underestimated based on overall immunogenicity data in humans and lack of parallelism with other, more classical immunisation methods. PRINCIPAL FINDINGS: Using malaria Liv

Externí odkaz: https://doaj.org/article/e7faa32e289c45b3ae692c9824755541

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Akademický článek

Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements.

Autor: Else Marie Agger, Ida Rosenkrands, Jon Hansen, Karima Brahimi, Brian S Vandahl, Claus Aagaard, Kerstin Werninghaus, Carsten Kirschning, Roland Lang, Dennis Christensen, Michael Theisen, Frank Follmann, Peter Andersen

Publikováno v: PLoS ONE, Vol 3, Iss 9, p e3116 (2008)

BACKGROUND: It is now emerging that for vaccines against a range of diseases including influenza, malaria and HIV, the induction of a humoral response is insufficient and a substantial complementary cell-mediated immune response is necessary for adeq

Externí odkaz: https://doaj.org/article/f7a3d3c923cf4956b513c2cd03d643c7

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The Plasmodium falciparum family of Rab GTPases

Autor: Tobias Spielmann, Karima Brahimi, Emmanuel Quevillon, Gordon Langsley, Edouard Yeramian, Debasish Chattopadhyay

Publikováno v: Gene. 306:13-25

Rab GTPases are key regulators of vesicular traffic in eukaryotic cells. Here we sought a global characterization and description of the Plasmodium falciparum family of Rab GTPases. We used a combination of bioinformatic analyses, experimental testin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426c41431f02bca9c7eb5fedb2080f29
https://doi.org/10.1016/s0378-1119(03)00381-0

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Long synthetic peptides encompassing thePlasmodium falciparum LSA3 are the target of human B and T cells and are potent inducers of B helper, T helper and cytolytic T cell responses in mice

Autor: Blanca Liliana Perlaza, Jean-Pierre Sauzet, Karima Brahimi, Giampietro Corradin, Aissatou Toure Balde, Pierre Druilhe, Adama Tall

Publikováno v: European Journal of Immunology. 31:2200-2209

We synthesized 17 long synthetic peptides (LSP) spanning the whole 200-kDa Plasmodium falciparum liver stage antigen-3 (LSA3), an antigen that induces protection in chimpanzee, and analyzed their immunogenicity in BALB/c mice and their antigenicity i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9eae28309f394094fa990a4bbda08ff
https://doi.org/10.1002/1521-4141(200107)31:7<2200::aid-immu2200>3.0.co

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Human Antibodies againstPlasmodium falciparumLiver-Stage Antigen 3 Cross-React withPlasmodium yoeliiPreerythrocytic-Stage Epitopes and Inhibit Sporozoite Invasion In Vitro and In Vivo

Autor: Claudine Guerin-Marchand, Karima Brahimi, Jean-Pierre Sauzet, Lbachir BenMohamed, Edgar Badell, Pierre Druilhe, Pierre Daubersies, George Snounou

Publikováno v: Infection and Immunity. 69:3845-3852

The development of a malaria preerythrocytic vaccine has been greatly influenced by the observation that sterile immunity could be experimentally induced in humans by immunization with Plasmodium falciparum radiation-attenuated sporozoites (9). The c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80745863b7f1bbddf76f8a4762372a7c
https://doi.org/10.1128/iai.69.6.3845-3952.2001

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High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules

Autor: Hélène Gras-Masse, Pierre Druilhe, Alan W. Thomas, Karima Brahimi, Lbachir BenMohamed, Jacqueline Wubben, Marc Bossus

Publikováno v: Vaccine. 18:2843-2855

We have investigated the immunogenicity in chimpanzees of twelve synthetic peptides derived from four new Plasmodium falciparum molecules expressed at pre-erythrocytic stages of the human malaria parasite. These parasite molecules were initially sele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e4a188fa9cf9c7a2b80c30284a7b9d
https://doi.org/10.1016/s0264-410x(00)00068-2

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Plasmodium falciparum asparagine and aspartate rich protein 2 is an evolutionary conserved protein whose repeats identify a new family of parasite antigens1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBankTM and DDJB data bases under the accession numbers Y08924 and Y08925.1

Autor: Gordon Langsley, Luiz Pereira da Silva, Géraldine Attal-Bonnefoy, Karima Brahimi, Jean-Christophe Barale

Publikováno v: Molecular and Biochemical Parasitology. 87:169-181

We describe here a new Plasmodium falciparum antigen, asparagine and aspartate rich protein 2 (PfAARP2) of 150 kDa, which is encoded by a unique gene on chromosome 1. PfAARP2 is first expressed 12 h post-invasion and accumulates in trophozoites and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34cf5ad183cfc0bff7726080598ca87b
https://doi.org/10.1016/s0166-6851(97)00065-0

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Biologie des vecteurs et transmission deplasmodium falciparum, p. malariae et p. ovaledans un village de savane d'afrique de l'ouest (Dielmo, Sénégal)

Autor: Fabrice Legros, Christophe Rogier, Lassana Konate, V. Petrarca, Diagne N, Oumar Faye, Karima Brahimi, Jean-François Trape

Publikováno v: Parasite. 1:325-333

Une etude entomologique longitudinale a ete effectuee a Dielmo, un village situe en zone de savane soudanienne au Senegal, d'avril 1990 a mars 1992. Les moustiques ont ete echantillonnes a partir de captures de nuit sur appâts humains et de pulveris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c358b2c4199039dd819db2afddf14264
https://doi.org/10.1051/parasite/1994014325

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Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity

Autor: Karima Brahimi, Lbachir BenMohamed, Jean-Pierre Sauzet, Pierre Druilhe, Blanca-Liliana Perlaza

Publikováno v: Malaria Journal, Vol 10, Iss 1, p 27 (2011)
Malaria Journal
Perlaza, BL; Sauzet, JP; Brahimi, K; Benmohamed, L; & Druilhe, P. (2011). Interferon-γ, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity. Malaria Journal, 10. doi: 10.1186/1475-2875-10-27. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1qh2j1h2

Immunity against the pre-erythrocytic stages of malaria is the most promising, as it is strong and fully sterilizing. Yet, the underlying immune effectors against the human Plasmodium falciparum pre-erythrocytic stages remain surprisingly poorly know

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5018860403fb941d948ee5866688fd
http://www.malariajournal.com/content/10/1/27

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