Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells

Autor: Michael Valente, Nils Collinet, Thien-Phong Vu Manh, Dimitri Popoff, Khalissa Rahmani, Karima Naciri, Gilles Bessou, Rejane Rua, Laurine Gil, Cyrille Mionnet, Pierre Milpied, Elena Tomasello, Marc Dalod

Publikováno v: Nature Immunology. 24:714-728

Plasmacytoid dendritic cells (pDCs) are the main source of type I interferon (IFN-I) during viral infections. Their other functions are debated, due to a lack of tools to identify and target them in vivo without affecting pDC-like cells and transitio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::739ab906d94afce38f086fdf17c3329a
https://doi.org/10.1038/s41590-023-01454-9

The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection

Autor: Jean-Luc Davignon, Karima Naciri, Rabie Chelbi, Gilles Bessou, Chuang Dong, Nils Collinet, Michael Valente, Geoffray Brelurut, Pierre Milpied, Abdenour Abbas, Morgane Thomas-Chollier, Noudjoud Attaf, Thien-Phong Vu Manh, Inaki Cervera-Marzal, Alexandra-Chloé Villani, Benjamin Rauwel, Denis Thieffry, Marc Dalod, Elena Tomasello

Publikováno v: Nature Immunology
Nature Immunology, Nature Publishing Group, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature Immunology, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature immunology

International audience; Plasmacytoid dendritic cells (pDCs) are a major source of type I interferon (IFN-I). What other functions pDCs exert in vivo during viral infections is controversial, and more studies are needed to understand their orchestrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd76519d3ec2c2f1de126656bc2665f9
https://hal.archives-ouvertes.fr/hal-02980944/file/2020_11_30_Abbas_et_al_2020_accepted_manuscript_for_HAL_small_size.pdf