Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Karim S Elayouby"'
Autor:
Elissavet Chartampila, Karim S Elayouby, Paige Leary, John J LaFrancois, David Alcantara-Gonzalez, Swati Jain, Kasey Gerencer, Justin J Botterill, Stephen D Ginsberg, Helen E Scharfman
Publikováno v:
eLife, Vol 12 (2024)
Maternal choline supplementation (MCS) improves cognition in Alzheimer’s disease (AD) models. However, the effects of MCS on neuronal hyperexcitability in AD are unknown. We investigated the effects of MCS in a well-established mouse model of AD wi
Externí odkaz:
https://doaj.org/article/0e246cdcf3d74bf2920d9ad020418a20
Autor:
Elissavet Chartampila, Karim S. Elayouby, Paige Leary, John J. LaFrancois, David Alcantara-Gonzalez, Swati Jain, Kasey Gerencer, Justin J. Botterill, Stephen D. Ginsberg, Helen E. Scharfman
Maternal choline supplementation (MCS) improves cognition in Alzheimer’s disease (AD) models. However, effects of MCS on neuronal hyperexcitability in AD are unknown. We investigated effects of MCS in a well-established mouse model of AD with hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c166ffca1d95d7b08978178716349238
https://doi.org/10.1101/2023.05.12.540428
https://doi.org/10.1101/2023.05.12.540428
Autor:
Christie D. Fowler, Karim S. Elayouby, Paul J. Kenny, Masago Ishikawa, Qun Lu, Angeline J. Dukes, Alexander C.W. Smith
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 8
J Neurosci
J Neurosci
Allelic variation inCHRNA3, the gene encoding the α3 nicotinic acetylcholine receptor (nAChR) subunit, increases vulnerability to tobacco dependence and smoking-related diseases, but little is known about the role for α3-containing (α3*) nAChRs in
Autor:
Stephanie P. B. Caligiuri, William M. Howe, Lauren Wills, Alexander C. W. Smith, Ye Lei, Purva Bali, Mary P. Heyer, Janna K. Moen, Jessica L. Ables, Karim S. Elayouby, Maya Williams, Clementine Fillinger, Zainab Oketokoun, Vanessa E. Lehmann, Alexandra G. DiFeliceantonio, Paul M. Johnson, Kristin Beaumont, Robert P. Sebra, Ines Ibanez-Tallon, Paul J. Kenny
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119 (46)
Hedgehog-interacting protein (HHIP) sequesters Hedgehog ligands to repress Smoothened (SMO)-mediated recruitment of the GLI family of transcription factors. Allelic variation in HHIP confers risk of chronic obstructive pulmonary disease and other smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9184c413621c8faa4ce5ae2957cf8d93
Autor:
Maya Williams, Alexander Duncan, Richard M. O'Connor, Maria Vittoria Micioni Di Bonaventura, Zuxin Chen, Jessica L. Ables, Xin-An Liu, William M. Howe, Avi Ma'ayan, Mary P. Heyer, Paul J. Kenny, Qun Lu, Clementine Fillinger, Masago Ishikawa, Purva Bali, Theodore M. Kamenecka, Karim S. Elayouby, Inés Ibañez-Tallon, Zichen Wang, Aron M. Geurts, Stephanie P.B. Caligiuri, Heidi C. O'Neill
Publikováno v:
Nature. 574:372-377
Diabetes is far more prevalent in smokers than non-smokers, but the underlying mechanisms of vulnerability are unknown. Here we show that the diabetes-associated gene Tcf7l2 is densely expressed in the medial habenula (mHb) region of the rodent brain
Autor:
Lauren Wills, Jessica L. Ables, Kevin M. Braunscheidel, Stephanie P.B. Caligiuri, Karim S. Elayouby, Clementine Fillinger, Masago Ishikawa, Janna K. Moen, Paul J. Kenny
Publikováno v:
Pharmacological reviews. 74(1)
Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also regulate the aversive properties of nicotine, sensitivity to which decrease