Výsledky vyhledávání - "Karim Mesbah"

Akademický článek

Hes1 is expressed in the second heart field and is required for outflow tract development.

Autor: Francesca Rochais, Mathieu Dandonneau, Karim Mesbah, Thérèse Jarry, Marie-Geneviève Mattei, Robert G Kelly

Publikováno v: PLoS ONE, Vol 4, Iss 7, p e6267 (2009)

Rapid growth of the embryonic heart occurs by addition of progenitor cells of the second heart field to the poles of the elongating heart tube. Failure or perturbation of this process leads to congenital heart defects. In order to provide further ins

Externí odkaz: https://doaj.org/article/52c12397b2c94294a0b863dac5e0ac35

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Loss of Tbx3 in murine neural crest reduces enteric glia and causes cleft palate, but does not influence heart development or bowel transit

Autor: Silvia Huerta López, Karim Mesbah, Christina M. Wright, Marina Avetisyan, Robert O. Heuckeroth, Anne M. Moon, Robert G. Kelly

Publikováno v: Developmental Biology
Developmental Biology, Elsevier, 2018, 444, pp.S337-S351. ⟨10.1016/j.ydbio.2018.09.017⟩
Developmental Biology, Elsevier, 2018, ⟨10.1016/j.ydbio.2018.09.017⟩
Developmental Biology, 2018, 444, pp.S337-S351. ⟨10.1016/j.ydbio.2018.09.017⟩

International audience; Transcription factors that coordinate migration, differentiation or proliferation of enteric nervous system (ENS) precursors are not well defined. To identify novel transcriptional regulators of ENS development, we performed m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d9907301f92868bcf197c0529d31d3
https://hal.archives-ouvertes.fr/hal-02117793

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Tbx1 Coordinates Addition of Posterior Second Heart Field Progenitor Cells to the Arterial and Venous Poles of the Heart

Autor: Brigitte Laforest, Robert H. Anderson, Robert G. Kelly, Marine Roux, M. Sameer Rana, Timothy J. Mohun, Stéphane Zaffran, Alexandre Francou, Christopher De Bono, Karim Mesbah, Mayyasa Rammah, Magali Théveniau-Ruissy, Jorge N. Domínguez, Vincent M. Christoffels

Publikováno v: Circulation Research
Circulation Research, American Heart Association, 2014, 115 (9), pp.790-9. ⟨10.1161/CIRCRESAHA.115.305020⟩
Circulation research, 115(9), 790-799. Lippincott Williams and Wilkins
Circulation Research, 2014, 115 (9), pp.790-9. ⟨10.1161/CIRCRESAHA.115.305020⟩

Rationale: Cardiac progenitor cells from the second heart field (SHF) contribute to rapid growth of the embryonic heart, giving rise to right ventricular and outflow tract (OFT) myocardium at the arterial pole of the heart, and atrial myocardium at t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbff184452b0f817048b6deba3b5090
https://doi.org/10.1161/circresaha.115.305020

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Tbx1, subpulmonary myocardium and conotruncal congenital heart defects

Autor: Pauline Parisot, Karim Mesbah, Magali Théveniau-Ruissy, Robert G. Kelly

Publikováno v: Birth Defects Research Part A: Clinical and Molecular Teratology; Vol 91

Conotruncal congenital heart defects, including defects in septation and alignment of the ventricular outlets, account for approximately a third of all congenital heart defects. Failure of the left ventricle to obtain an independent outlet results in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5f29ad938859e5642d93481bb22a61
https://doi.org/10.1002/bdra.20803

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Decreased Levels of Embryonic Retinoic Acid Synthesis Accelerate Recovery From Arterial Growth Delay in a Mouse Model of DiGeorge Syndrome

Autor: Karen Niederreither, Robert G. Kelly, Karim Mesbah, Stéphane Zaffran, Lucile Ryckebüsch, Fanny Bajolle, Nicolas Bertrand

Publikováno v: Circulation Research
Circulation Research, American Heart Association, 2010, 106 (4), pp.686-94. ⟨10.1161/CIRCRESAHA.109.205732⟩
Circulation Research, American Heart Association, 2010, 106 (4), pp.686-94
Circulation Research, 2010, 106 (4), pp.686-94. ⟨10.1161/CIRCRESAHA.109.205732⟩

Rationale : Loss of Tbx1 and decrease of retinoic acid (RA) synthesis result in DiGeorge/velocardiofacial syndrome (DGS/VCFS)-like phenotypes in mouse models, including defects in septation of the outflow tract of the heart and anomalies of pharyngea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce27702c0461b0a9513f67850834a75
https://doi.org/10.1161/circresaha.109.205732

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Expression of Slit and Robo Genes in the Developing Mouse Heart

Autor: Orit Wolstein, Laurent Dupays, Timothy J. Mohun, Nicolas Bertrand, Virginia E. Papaioannou, Karim Mesbah, Bruno Hudry, Caroline Medioni, Richard P. Harvey, Stéphane Zaffran, Andrew J. Washkowitz

Publikováno v: Developmental Dynamics; Vol 239
Developmental Dynamics
Developmental Dynamics, Wiley, 2010, epub ahead of print. ⟨10.1002/dvdy.22449⟩

International audience; Development of the mammalian heart is mediated by complex interactions between myocardial, endocardial, and neural crest-derived cells. Studies in Drosophila have shown that the Slit-Robo signaling pathway controls cardiac cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56992cd1efeccc5f6e5c12817527ffb

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The del22q11.2 Candidate Gene Tbx1 Controls Regional Outflow Tract Identity and Coronary Artery Patterning

Autor: Olivier Ghez, Mathieu Dandonneau, Robert G. Kelly, Magali Théveniau-Ruissy, Karim Mesbah, Lucile Miquerol, Marie-Geneviève Mattei

Publikováno v: Circulation Research. 103:142-148

TBX1 , encoding a T-box containing transcription factor, is the major candidate gene for del22q11.2 or DiGeorge syndrome, characterized by craniofacial and cardiovascular defects including tetralogy of Fallot and common arterial trunk. Mice lacking T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17e9bfdf4f17a9fdcb964828536974b1
https://doi.org/10.1161/circresaha.108.172189

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TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field

Autor: Karim Mesbah, Edouard Saint-Michel, Alexandre Francou, Robert G. Kelly

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (22), pp.4320-31. ⟨10.1242/dev.115022⟩
Development (Cambridge, England), 2014, 141 (22), pp.4320-31. ⟨10.1242/dev.115022⟩

International audience; Elongation of the vertebrate heart occurs by progressive addition of second heart field (SHF) cardiac progenitor cells from pharyngeal mesoderm to the poles of the heart tube. The importance of these cells in the etiology of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491998a844d4176c8a27d79aa8810243
https://hal.archives-ouvertes.fr/hal-01112641

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FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry

Autor: Timothy J. Mohun, Rachel Sturny, Karim Mesbah, Saverio Bellusci, Francesca Rochais, Robert G. Kelly, Michael B. Bennett, Cho-Ming Chao

Publikováno v: Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2014, 104 (3), pp.432-42. ⟨10.1093/cvr/cvu232⟩
Cardiovascular Research, 2014, 104 (3), pp.432-42. ⟨10.1093/cvr/cvu232⟩

International audience; AIMS:Cardiomyocyte proliferation gradually declines during embryogenesis resulting in severely limited regenerative capacities in the adult heart. Understanding the developmental processes controlling cardiomyocyte proliferati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17bee6f4d28648726d0350d2ae48c71
https://pubmed.ncbi.nlm.nih.gov/25344367

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Signaling pathways controlling second heart field development

Autor: Karim Mesbah, Francesca Rochais, Robert G. Kelly

Publikováno v: Circulation research. 104(8)

Insight into the mechanisms underlying congenital heart defects and the use of stem cells for cardiac repair are major research goals in cardiovascular biology. In the early embryo, progenitor cells in pharyngeal mesoderm contribute to the rapid grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44404e6042cd4f8b91e4ce0f848c0dde
https://pubmed.ncbi.nlm.nih.gov/19390062

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