Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Karim Majzoub"'
Autor:
Emma Partiot, Barbara Gorda, Willy Lutz, Solène Lebrun, Pierre Khalfi, Stéphan Mora, Benoit Charlot, Karim Majzoub, Solange Desagher, Gowrishankar Ganesh, Sophie Colomb, Raphael Gaudin
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 1004-1026 (2024)
Abstract Viral neuroinfections represent a major health burden for which the development of antivirals is needed. Antiviral compounds that target the consequences of a brain infection (symptomatic treatment) rather than the cause (direct-acting antiv
Externí odkaz:
https://doaj.org/article/1568c0079b624b088ce4c11aa333391c
Autor:
Pierre Khalfi, Zoé Denis, Joe McKellar, Giovanni Merolla, Carine Chavey, José Ursic-Bedoya, Lena Soppa, Leonora Szirovicza, Udo Hetzel, Jeremy Dufourt, Cedric Leyrat, Nora Goldmann, Kaku Goto, Eloi Verrier, Thomas F Baumert, Dieter Glebe, Valérie Courgnaud, Damien Gregoire, Jussi Hepojoki, Karim Majzoub
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012060 (2024)
The recent discovery of Hepatitis D (HDV)-like viruses across a wide range of taxa led to the establishment of the Kolmioviridae family. Recent studies suggest that kolmiovirids can be satellites of viruses other than Hepatitis B virus (HBV), challen
Externí odkaz:
https://doaj.org/article/ada71d4cf9dd4a64980a7c9aa774c4a5
Autor:
Carla Eller, Laura Heydmann, Che C. Colpitts, Houssein El Saghire, Federica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S. Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E. Root, Eloi R. Verrier, Thomas F. Baumert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Here the authors perform a gain-of-function screen and identify CDKN2C as a host factor for HBV replication, inducing cell cycle arrest and expression of HBV transcription enhancers. CDKN2C expression correlates with disease progression suggesting a
Externí odkaz:
https://doaj.org/article/0742f94d66504c4986045226266777a1
Autor:
Andreas S. Puschnik, Caleb D. Marceau, Yaw Shin Ooi, Karim Majzoub, Natalie Rinis, Joseph N. Contessa, Jan E. Carette
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3032-3039 (2017)
The mosquito-borne flaviviruses include important human pathogens such as dengue, Zika, West Nile, and yellow fever viruses, which pose a serious threat for global health. Recent genetic screens identified endoplasmic reticulum (ER)-membrane multipro
Externí odkaz:
https://doaj.org/article/9efa46a54a9444a99aa2fe10bb935275
Autor:
Lauriane Kuhn, Karim Majzoub, Evelyne Einhorn, Johana Chicher, Julien Pompon, Jean-Luc Imler, Philippe Hammann, Carine Meignin
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2249-2258 (2017)
Receptor for Activated protein C kinase 1 (RACK1) is a scaffold protein that has been found in association with several signaling complexes, and with the 40S subunit of the ribosome. Using the model organism Drosophila melanogaster, we recently showe
Externí odkaz:
https://doaj.org/article/853b068f78b7454ca409975f3530513e
Autor:
Miguel Mata, Steven Neben, Karim Majzoub, Jan Carette, Muthukumar Ramanathan, Paul A Khavari, Peter Sarnow
Publikováno v:
PLoS Pathogens, Vol 15, Iss 5, p e1007467 (2019)
Hepatitis C virus (HCV) depends on liver-specific microRNA miR-122 for efficient viral RNA amplification in liver cells. This microRNA interacts with two different conserved sites at the very 5' end of the viral RNA, enhancing miR-122 stability and p
Externí odkaz:
https://doaj.org/article/543989b0ed744d50afea5df04962f138
Autor:
Emma Abernathy, Roberto Mateo, Karim Majzoub, Nick van Buuren, Sara W Bird, Jan E Carette, Karla Kirkegaard
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e2006926 (2019)
Many viruses interface with the autophagy pathway, a highly conserved process for recycling cellular components. For three viral infections in which autophagy constituents are proviral (poliovirus, dengue, and Zika), we developed a panel of knockouts
Externí odkaz:
https://doaj.org/article/71bd9884212d42089ed39a01a2fbaf58
Publikováno v:
Viruses, Vol 11, Iss 8, p 758 (2019)
Animal cells have evolved dedicated molecular systems for sensing and delivering a coordinated response to viral threats. Our understanding of these pathways is almost entirely defined by studies in humans or model organisms like mice, fruit flies an
Externí odkaz:
https://doaj.org/article/7e10f569699149669f84dc05f6135b27
Autor:
Pierre Khalfi, Zoé Denis, Giovanni Merolla, Carine Chavey, José Ursic-Bedoya, Lena Soppa, Leonora Szirovicza, Udo Hetzel, Jeremy Dufourt, Cedric Leyrat, Nora Goldmann, Kaku Goto, Eloi Verrier, Thomas F. Baumert, Dieter Glebe, Valérie Courgnaud, Damien Grégoire, Jussi Hepojoki, Karim Majzoub
The recent discovery of Hepatitis D (HDV)-likeviruses across a wide range of taxa led to the establishment of theKolmioviridaefamily. Recent studies suggest that kolmiovirids can be satellites of viruses other than Hepatitis B virus (HBV), challengin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::071e6776eb010cac80aab2f9203ac64e
https://doi.org/10.1101/2023.05.17.541162
https://doi.org/10.1101/2023.05.17.541162
Autor:
Garrett P. Larson, David Johnson, James A. Stewart, Rebecca Sutphen, Peter J. O'Dwyer, John M. Kirkwood, Al B. Benson, Mary B. Daly, Jeffrey Weitzel, Theodore G. Krontiris, John J. Rossi, Jessica Alluin, Guillermo E. Rivas, Karim Majzoub, Laurent F. Thomas, David Smith, Sierra M. Li, Jacob Biesinger, Pål Sætrom
Supplementary Figure and Table Legends from A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a23044f59441af4e1582e00d9b8d275
https://doi.org/10.1158/0008-5472.22379138
https://doi.org/10.1158/0008-5472.22379138