Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Karim Mahiddine"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) form a collection of antigen-presenting cells (APCs) that are distributed throughout the body. Conventional DCs (cDCs), which include the cDC1 and cDC2 subsets, and plasmacytoid DCs (pDCs) constitute the two major ontogenically
Externí odkaz:
https://doaj.org/article/f17a0ebac99644a8b1e0ffad71c8f8ca
Autor:
Johan Siewiera, Tara I. McIntyre, Kelly M. Cautivo, Karim Mahiddine, Damon Rideaux, Ari B. Molofsky, Adrian Erlebacher
Publikováno v:
Immunity. 56:606-619.e7
Autor:
Amandine Créquer-Grandhomme, Stephany Ma, Clifford A. Lowell, Adrian Erlebacher, Adam Blaisdell, Karim Mahiddine
Publikováno v:
The Journal of clinical investigation, vol 130, iss 1
Polymorphonuclear neutrophils (PMNs) are increasingly recognized to influence solid tumor development, but why their effects are so context dependent and even frequently divergent remains poorly understood. Using an autochthonous mouse model of uteri
Publikováno v:
The Journal of Immunology. 195:1964-1973
Multiple studies highlighted the overtly self-reactive T cell repertoire in the diabetes-prone NOD mouse. This autoreactivity has primarily been linked to defects in apoptosis induction during central tolerance. Previous studies suggested that thymus
Autor:
Sylvie Guerder, Abdoulraouf Ramadan, Lennart T. Mars, Paul Menut, Karim Mahiddine, Laurent Serre, Maeva Girard, Nelly Rouquié, Bertrand Leobon, Liliana E. Lucca
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(11)
The genetic predisposition to multiple sclerosis (MS) is most strongly conveyed by MHC class II haplotypes, possibly by shaping the autoimmune CD4 T cell repertoire. Whether Ag-processing enzymes contribute to MS susceptibility by editing the peptide
Autor:
Marcel Deckert, Sophie Tartare-Deckert, Elodie Guillemot, Frédéric Larbret, Valérie Verhasselt, Nicholas Dubois, Frédéric Brau, Karim Mahiddine
Publikováno v:
Journal of Leukocyte Biology. 94:531-539
Actin cytoskeleton plays a critical role in regulating T cell motility and activation. However, the lack of a real-time quantitative method to analyze actin assembly has limited the progress toward understanding actin regulation. Here, we describe a
Autor:
Frédéric Larbret, Karim Mahiddine, Alain Bernard, Hanen Bziouech, Ghislaine Bernard, Aude Mallavialle
Publikováno v:
European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (6), pp.1460-1471. ⟨10.1002/eji.201546143⟩
European Journal of Immunology, Wiley-VCH Verlag, 2016, 46 (6), pp.1460-1471. ⟨10.1002/eji.201546143⟩
International audience; CD1a expression is considered one of the major characteristics qualifying in vitro human dendritic cells (DCs) during their generation process. Here, we report that CD1A transcription is regulated by a mechanism involving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c472ed48147a8475c6f63644569a6f
https://hal.umontpellier.fr/hal-02297566
https://hal.umontpellier.fr/hal-02297566
Autor:
Paul A. Gleeson, Aurore Brémond, Alain Bernard, Ophélie Meynet, Karim Mahiddine, Katia Scotlandi, Mélanie Tichet, Sylvie Coito, Ghislaine Bernard, Pierre Gounon, Jean Philippe Breittmayer
Publikováno v:
Blood. 113:347-357
By presenting antigenic peptides on the cell surface, human leukocyte antigen (HLA) class I molecules are critical for immune defense. Their surface density determines, to a large extent, the level of CD8+ T cell–dependent immune reactions; their l
Publikováno v:
Current opinion in immunology. 25(6)
Type 1 diabetes is a T cell mediated autoimmune disease where both central and peripheral mechanisms effect T cell tolerance induction. Dendritic cells (DCs) are key regulators of innate and adaptive immune responses. They significantly contribute to
Autor:
Mouna Sghaier, Hanene Bziouech, Karim Mahiddine, Ghislaine Bernard, Alain Bernard, Aude Malavialle
Publikováno v:
Human Immunology. 72:S181