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pro vyhledávání: '"Karim Macary"'
Autor:
Philippe Cluzeau, Hassan Julien Imogai, Mark Epping-Jordan, Alexandre Raux, Guillaume Albert Jacques Duvey, Jean-Philippe Rocher, Gregor James Macdonald, José María Cid, Ana Isabel de Lucas, Juan Antonio Vega, Vanthea Nhem, Francis Derouet, Gary Tresadern, Andrés A. Trabanco, Christelle Boléa, José Ignacio Andrés, Robert Johannes Lütjens, Daniel Oehlrich, Karim Macary, Encarnación Matesanz, Hilde Lavreysen, Terry Patrick Finn, Sonia Poli, Jessica Muller, María Lourdes Linares, Nicolas Poirier, Francoise Girard, Julen Oyarzabal, Emilie Chamelot, Emmanuel Le Poul
Publikováno v:
ACS Chemical Neuroscience. 1:788-795
The discovery and characterization of compound 48, a selective and in vivo active mGlu2 receptor positive allosteric modulator (PAM), are described. A key to the discovery was the rational exploration of the initial HTS hit 13 guided by an overlay mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f590c750783d25cc6a29610597f8f26
https://doi.org/10.1021/cn1000638
https://doi.org/10.1021/cn1000638
