Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Karim H Shalaby"'
Autor:
John Mac Sharry, Karim H Shalaby, Cinzia Marchica, Soroor Farahnak, Tien Chieh-Li, Susan Lapthorne, Salman T Qureshi, Fergus Shanahan, James G Martin
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98648 (2014)
Varying concentrations of lipopolysaccharide (LPS) in ovalbumin (OVA) may influence the airway response to allergic sensitization and challenge. We assessed the contribution of LPS to allergic airway inflammatory responses following challenge with LP
Externí odkaz:
https://doaj.org/article/71be7e6fe915453ea355f93cf2145ce5
Autor:
Leonie Enderle, Karim H. Shalaby, Maryna Gorelik, Alexander Weiss, Levi L. Blazer, Marcin Paduch, Lia Cardarelli, Anthony Kossiakoff, Jarrett J. Adams, Sachdev S. Sidhu
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
In order to direct T cells to specific features of solid cancer cells, we engineered a bispecific antibody format, named Dual Antigen T cell Engager (DATE), by fusing a single-chain variable fragment targeting CD3 to a tumor-targeting antigen-binding
Externí odkaz:
https://doaj.org/article/777c600eb1a04893b2cef9f6918ac3c1
Autor:
Maryna Gorelik, Alexander Weiss, Jarrett Adams, Sachdev S. Sidhu, Anthony A. Kossiakoff, Marcin Paduch, Lia Cardarelli, Karim H. Shalaby, Leonie Enderle, Levi L. Blazer
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
In order to direct T cells to specific features of solid cancer cells, we engineered a bispecific antibody format, named Dual Antigen T cell Engager (DATE), by fusing a single-chain variable fragment targeting CD3 to a tumor-targeting antigen-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea767b7206bb797aeda0ca536e21aff
http://europepmc.org/articles/PMC8253144
http://europepmc.org/articles/PMC8253144
Mechanical consequences of allergic induced remodeling on mice airway resistance and compressibility
Autor:
Annette Robichaud, James G. Martin, Mauro Novali, Toby K. McGovern, Karim H. Shalaby, Thomas F. Schuessler, Andrea Benedetti, Liah Fereydoonzad
Publikováno v:
Respiratory Physiology & Neurobiology. 218:11-20
The effect of remodeling on airway function is uncertain. It may affect airway compressibility during forced expirations differently than airflow resistance, providing a tool for its assessment. The aim of the current study was to compare the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795e61d842d408b28bdab36cc231f8f1
https://doi.org/10.1016/j.resp.2015.07.007
https://doi.org/10.1016/j.resp.2015.07.007
Publikováno v:
International Journal of Materials, Mechanics and Manufacturing. 4:195-199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87ab95f11935f5dc24d3805a38baa76
https://doi.org/10.7763/ijmmm.2016.v4.255
https://doi.org/10.7763/ijmmm.2016.v4.255
Autor:
Karim H, Shalaby, Miranda R, Lyons-Cohen, Gregory S, Whitehead, Seddon Y, Thomas, Immo, Prinz, Hideki, Nakano, Donald N, Cook
Publikováno v:
The Journal of allergy and clinical immunology. 142(4)
Mechanisms that elicit mucosal TWe sought to understand whether maintenance of lung TAnimals were exposed repeatedly to aspiration of ovalbumin alone or together with environmental adjuvants, including common house dust extract (HDE), to test their r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51bb3a0f499b7bd890e6ec2670cb5bad
https://pubmed.ncbi.nlm.nih.gov/29154958
https://pubmed.ncbi.nlm.nih.gov/29154958
Autor:
Keiko Nakano, Seddon Y. Thomas, Karim H. Shalaby, James M. Ward, Gordon P. Flake, Hideki Nakano, Donald N. Cook, Gregory S. Whitehead, Timothy P. Moran
Asthma is associated with exposure to a wide variety of allergens and adjuvants. The extent to which overlap exists between the cellular and molecular mechanisms triggered by these various agents is poorly understood, but it might explain the differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6c0694e266dbbc30f22ad301fb88b5
Autor:
Karim H. Shalaby, Alexandra Allard-Coutu, Brian J. Day, Michael O'Sullivan, Emily Nakada, Salman T. Qureshi, James G. Martin
Publikováno v:
The Journal of Immunology. 191:922-933
Oxidative stress in allergic asthma may result from oxidase activity or proinflammatory molecules in pollens. Signaling via TLR4 and its adaptor Toll–IL-1R domain–containing adapter inducing IFN-β (TRIF) has been implicated in reactive oxygen sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ec83c7d9c83affa07aae74165923c6
https://doi.org/10.4049/jimmunol.1103644
https://doi.org/10.4049/jimmunol.1103644
Autor:
Kimitake Tsuchiya, Saba Al Heialy, Karim H. Shalaby, Salman T. Qureshi, Woong-Kyung Suh, James G. Martin, Toby K. McGovern, Paul-André Risse, Soroor Farahnak
Publikováno v:
Immunology. 152(1)
The Toll-like Receptor (TLR) adaptor proteins Myeloid Differentiating Factor 88 (MyD88) and Toll, interleukin-1 Receptor and Resistance protein (TIR) domain-containing adaptor inducing interferon-β (TRIF) comprise the two principal limbs of the TLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1165cd7a59900e91fc555a55fe3bdcfe
https://pubmed.ncbi.nlm.nih.gov/28502093
https://pubmed.ncbi.nlm.nih.gov/28502093
Autor:
James G. Martin, C. Rioux, Alexandra Allard-Coutu, Taisuke Jo, Nobuaki Hirota, Emily Nakada, Karim Maghni, Kimitake Tsuchiya, Salman T. Qureshi, Karim H. Shalaby
Publikováno v:
The Journal of Immunology. 189:2793-2804
Modulation of adaptive immune responses via the innate immune pattern recognition receptors, such as the TLRs, is an emerging strategy for vaccine development. We investigated whether nasal rather than intrapulmonary application of Protollin, a mucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cc2175624353d71718e967dfa45750
https://doi.org/10.4049/jimmunol.1201194
https://doi.org/10.4049/jimmunol.1201194