Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Karim Gariani"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Diabetes mellitus is a complex chronic disease, considered as one of the most common metabolic disorders worldwide, posing a major threat to global public health. Ferroptosis emerges as a novel mechanism of programmed cell death, distinct from apopto
Externí odkaz:
https://doaj.org/article/11b0f6499093496f9310948089de48f3
Autor:
Pablo Jané, Xiaoying Xu, Vincent Taelman, Eduardo Jané, Karim Gariani, Rebecca A. Dumont, Yonathan Garama, Francisco Kim, María del Val Gomez, Martin A. Walter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Understanding human disease on a molecular level, and translating this understanding into targeted diagnostics and therapies are central tenets of molecular medicine1. Realizing this doctrine requires an efficient adaptation of molecular dis
Externí odkaz:
https://doaj.org/article/3c2116eb1b54488aa6f4dc39d6d46a3d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The effect of sodium-glucose co-transporter-2 (SGLT-2) inhibitors on cardiovascular and renal outcomes has not been systematically reviewed across baseline kidney function groups. We conducted a systematic review and meta-analysis of randomi
Externí odkaz:
https://doaj.org/article/399210e51d194ef9aefcb20d0271ab51
Autor:
Thanh T. Nguyen, Shibo Wei, Thu Ha Nguyen, Yunju Jo, Yan Zhang, Wonyoung Park, Karim Gariani, Chang-Myung Oh, Hyeon Ho Kim, Ki-Tae Ha, Kyu Sang Park, Raekil Park, In-Kyu Lee, Minho Shong, Riekelt H. Houtkooper, Dongryeol Ryu
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1595-1619 (2023)
Abstract Mitochondria, ubiquitous double-membrane-bound organelles, regulate energy production, support cellular activities, harbor metabolic pathways, and, paradoxically, mediate cell fate. Evidence has shown mitochondria as points of convergence fo
Externí odkaz:
https://doaj.org/article/69b80a65f8c146e29d7c4b1cbf007852
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
Diabetes is a chronic disease associated with numerous complications including diabetic foot disorders, which are associated with significant morbidity and mortality as well as high costs. The costs associated with diabetic foot disorders comprise th
Externí odkaz:
https://doaj.org/article/7abd8f0782624d3d98a24cf28e62877c
Autor:
Aurel T. Tankeu, Despina Christina Pavlidou, Andrea Superti-Furga, Karim Gariani, Christel Tran
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Background Excess weight is a rising concern in patients with phenylketonuria (PKU). It is commonly observed in children and adolescents with PKU; but data on adults are inconsistent. This review aims to summarize available data on excess we
Externí odkaz:
https://doaj.org/article/332dc4c695084e9ea894cfb94a935e06
Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity in the same individual, characterized by of the co-presence of body fat accumulation and muscle loss. This condition is currently a major concern as it is associated with frai
Externí odkaz:
https://doaj.org/article/48e42efa732d420d8df2b61ecf09ead8
Autor:
Mohamed Asrih, Flore Sinturel, Richard Dubos, Idris Guessous, Zoltan Pataky, Charna Dibner, François R Jornayvaz, Karim Gariani
Publikováno v:
Endocrine Connections, Vol 11, Iss 7, Pp 1-8 (2022)
Objective: Growth differentiation factor-15 (GDF15), a key metabolic regulator, is associated with obesity and diabetes in which sex-specific differences have been reported. Thus, we assessed whether GDF15 could be dependent on sex in diabetes and/or
Externí odkaz:
https://doaj.org/article/26b2301f626a4edcbedd8ea043198559
Autor:
Ilker Uçkay, MD, Dan Lebowitz, MD, Benjamin Kressmann, RN, Elodie von Dach, RN, Benjamin A. Lipsky, MD, Karim Gariani, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 3, Pp 250-256 (2022)
Objective: To assess the outcomes of diabetic foot infections (DFIs) due to Pseudomonas aeruginosa. Patients and Methods: From April 24, 2013 to July 31, 2016, we analyzed data from patients prospectively enrolled in our clinical pathway of DFIs, com
Externí odkaz:
https://doaj.org/article/d5d4428d13ae4b15895f6489298e86de
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 316 (2023)
In diabetic foot infections (DFI), the clinical virulence of skin commensals are generally presumed to be low. In this single-center study, we divided the wound isolates into two groups: skin commensals (coagulase-negative staphylococci, micrococci,
Externí odkaz:
https://doaj.org/article/7a6ef1044289434bb2b2299d0253603b