Metabolome Profiling by HRMAS NMR Spectroscopy of Pheochromocytomas and Paragangliomas Detects SDH Deficiency: Clinical and Pathophysiological Implications

Autor: Alessio Imperiale, François-Marie Moussallieh, Philippe Roche, Stéphanie Battini, A. Ercument Cicek, Frédéric Sebag, Laurent Brunaud, Anne Barlier, Karim Elbayed, Anderson Loundou, Philippe Bachellier, Bernard Goichot, Constantine A. Stratakis, Karel Pacak, Izzie-Jacques Namer, David Taïeb

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 1, Pp 55-65 (2015)

Succinate dehydrogenase gene (SDHx) mutations increase susceptibility to develop pheochromocytomas/paragangliomas (PHEOs/PGLs). In the present study, we evaluate the performance and clinical applications of 1H high-resolution magic angle spinning (HR

Externí odkaz: https://doaj.org/article/e4856ee55ca4478eb8e67ed0983f47f4

Synthesis and

Autor: Hassan, Srour, Alexis, Gosset, François-Marie, Moussallieh, Karim, Elbayed, Elena, Giménez-Arnau, Jean-Pierre, Lepoittevin

Publikováno v: Chemical research in toxicology. 35(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba79bd83bcb032ff7d0104613f8ad309
https://pubmed.ncbi.nlm.nih.gov/35976686

In Situ Alkylation of Reconstructed Human Epidermis by Methyl Methanesulfonate: A Quantitative HRMAS NMR Chemical Reactivity Mapping

Autor: Hassan Srour, Elena Giménez-Arnau, François-Marie Moussallieh, Jean-Pierre Lepoittevin, Karim Elbayed

Publikováno v: Chemical Research in Toxicology
Chemical Research in Toxicology, American Chemical Society, 2020, ⟨10.1021/acs.chemrestox.0c00362⟩
Chemical Research in Toxicology, 2020, ⟨10.1021/acs.chemrestox.0c00362⟩

Allergic contact dermatitis (ACD) is a reaction of the immune system resulting from skin sensitization to an exogenous hazardous chemical and leading to the activation of antigen-specific T-lymphocytes. The adverse outcome pathway (AOP) for skin sens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38290fa9325f1ca0a773a5869ee183dd
https://hal.archives-ouvertes.fr/hal-03009760/document

A Metabolomic Approach (1H HRMAS NMR Spectroscopy) Supported by Histology to Study Early Post-transplantation Responses in Islet-transplanted Livers

Autor: Jean-Pierre Gies, Elisa Ruhland, E. Seyfritz, Kevin Vivot, Karim Elbayed, A. Langlois, Elisa Maillard, Séverine Sigrist, Nathalie Reix, Nathalie Jeandidier, Michel Pinget, Izzie Jacques Namer, Malika A. Benahmed, William Bietiger

Publikováno v: International Journal of Biological Sciences. 12:1168-1180

Intrahepatic transplantation of islets requires a lot of islets because more than 50% of the graft is lost during the 24 hours following transplantation. We analyzed, in a rat model, early post-transplantation inflammation using systemic inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a3302daa36c3d9a0f9ab006667dcf81
https://doi.org/10.7150/ijbs.15189

Rapid Assessment of Fish Freshness and Quality by 1H HR-MAS NMR Spectroscopy

Autor: C. Heude, E. Lemasson, Karim Elbayed, Martial Piotto

Publikováno v: Food Analytical Methods. 8:907-915

A new analytical method that allows the rapid assessment of fish freshness and quality is presented. The method is based on 1H high-resolution magic angle spinning (HR-MAS) NMR spectroscopy and allows the rapid determination of two well-established i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e36861a2dcb1788c4b3d433e1f5cfeda
https://doi.org/10.1007/s12161-014-9969-5