Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Karim A. Sarhane"'
Autor:
Benjamin R. Slavin, Karim A. Sarhane, Nicholas von Guionneau, Phillip J. Hanwright, Chenhu Qiu, Hai-Quan Mao, Ahmet Höke, Sami H. Tuffaha
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Patients who sustain peripheral nerve injuries (PNIs) are often left with debilitating sensory and motor loss. Presently, there is a lack of clinically available therapeutics that can be given as an adjunct to surgical repair to enhance the regenerat
Externí odkaz:
https://doaj.org/article/705ccb7e91ab45e98100da809d0bfd14
Autor:
Karim A. Sarhane, MD, MSc, Chenhu Qiu, PhD candidate, Benjamin R. Slavin, MD candidate, Nicholas Hricz, BS, Marcos Iglesias, PhD, DVM, Nicholas von Guionneau, MBBS, Philip J. Hanwright, MD, Ruifa Mi, MD, PhD, Ahmet Höke, MD, PhD, Hai-Quan Mao, PhD, Sami H. Tuffaha, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 75-76 (2020)
Externí odkaz:
https://doaj.org/article/c764d3883e024194b79e61e12932fcb5
Autor:
Karim A. Sarhane, MD, MSc, Heather Shappell, PhD, Benjamin Slavin, BS, Nicholas von Guinneau, MD, Philip Hanwright, MD, Gregory H. Borschel, MD, Sami H. Tuffaha, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 7, Iss 4S, Pp 114-115 (2019)
Externí odkaz:
https://doaj.org/article/66152c995e1b4fbe984752af1f3f2f49
Autor:
Karim A. Sarhane, MD, MSc, José M. Flores, MPH, Carisa M. Cooney, MPH, Francis M. Abreu, BS, Marcelo Lacayo, MD, Pablo A. Baltodano, MD, Zuhaib Ibrahim, MD, Mohammed Alrakan, MD, Gerald Brandacher, MD, Gedge D. Rosson, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 1, Iss 5, p e30 (2013)
Background: Preoperative anemia is independently associated with adverse outcomes after general and cardiac surgery. Outcomes after breast reconstruction are not established. We assessed the effect of preoperative anemia on 30-day postoperative morbi
Externí odkaz:
https://doaj.org/article/2ac268e9c9774232af0598f35e246b94
Autor:
Nicholas von Guionneau, Sami H. Tuffaha, Hai-Quan Mao, Michael J. Lan, Gregory P. Howard, Sashank Reddy, Karim A. Sarhane, Thomas G.W. Harris, Jennifer Rath, Chenhu Qiu, Harsha Malapati, Philip J. Hanwright, Yang Zhou, Ahmet Hoke
Publikováno v:
Biomaterials. 280
Functional recovery following peripheral nerve injury is limited by progressive atrophy of denervated muscle and Schwann cells (SCs) that occurs during the long regenerative period prior to end-organ reinnervation. Insulin-like growth factor 1 (IGF-1
Autor:
Nicholas von Guionneau, Ahmet Hoke, Sami H. Tuffaha, Karim A. Sarhane, Paul S. Cederna, Thomas G.W. Harris, Philip J. Hanwright, Stephen W.P. Kemp, Jennifer Rath
Publikováno v:
Muscle & Nerve. 60:437-442
BACKGROUND Reliable measurement of functional recovery is critical in translational peripheral nerve regeneration research. Behavioral functional assessments such as volitional grip strength testing (vGST) are limited by inherent behavioral variabili
Autor:
Zuhaib Ibrahim, Christopher R. Cashman, W. P. Andrew Lee, Justin M. Broyles, Russell Martin, Damon S. Cooney, Ahmet Hoke, Ruifa Mi, Karim A. Sarhane, Gerald Brandacher, Kellin Krick, Hai-Quan Mao, Sami H. Tuffaha
Publikováno v:
Neurotherapeutics
Functional recovery following nerve injury declines when target re-innervation is delayed. Currently, no intervention exists to improve outcomes after prolonged denervation. We explored the neuroregenerative effects of glial cell line–derived neuro
Autor:
Justin M. Broyles, Hai-Quan Mao, Gerald Brandacher, W. P. Andrew Lee, Damon S. Cooney, Ahmet Hoke, Kellin Krick, Ruifa Mi, Christopher R. Cashman, Zhi Cheng Yao, Russell Martin, Karim A. Sarhane, Nijaguna B. Prasad, Sami H. Tuffaha, Zuhaib Ibrahim
Publikováno v:
Acta Biomaterialia. 88:332-345
Functional outcomes following nerve repair remain suboptimal. Scarring at the repair site is a major impediment to regeneration. A biomaterial scaffold applied around the coaptation site that decreases inflammation holds great potential in reducing s
Autor:
BS Chenhu Qiu, Karim A. Sarhane, BS Matthew Generoso, BS Connor Glass, Alison L. Wong, Mbbs Nicholas von Guionneau, MBChB Thomas G.W. Harris, BS Nicholas Hricz, Ahmet Hōke, Sami H. Tuffaha, BS Harsha Malapati, Philip J. Hanwright, Hai-Quan Mao, Kara Segna
Publikováno v:
Plastic and Reconstructive Surgery Global Open
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7S, Pp 13-14 (2021)
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7S, Pp 13-14 (2021)
Purpose: Insulin-like growth factor 1 (IGF-1) is a potent mitogen with the potential to enhance axonal regeneration and minimize muscle atrophy and Schwann cell senescence following prolonged denervation after peripheral nerve injury. IGF-1 is a smal
Autor:
Ahmet Hoke, Heather Shappell, Nicholas Hricz, Yinan Guo, Michael Grzelak, Ruifa Mi, Irene Aran Chang, Benjamin R. Slavin, Karim A. Sarhane, Alison L. Wong, Harsha Malapati, Nicholas von Guionneau, Sami H. Tuffaha
Publikováno v:
Experimental neurology. 339
Functional recovery following peripheral nerve injury worsens with increasing durations of delay prior to repair. From the time of injury until re-innervation occurs, denervated muscle undergoes progressive atrophy that limits the extent to which mot