Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Karim, Labib"'
Autor:
Md Ariful Haque, Liton Baroi, Ismat Ara Chowdhury Koly, Md Shakibul Hasan, Faiza Mahmud, Sifat Ara Eva, Moinul Karim Labib, Hazika Tuz-Zohura Nafisa, Salwa Islam, Irfat Islam Eva, Md. Rafiqul Islam, Lita Bose, Faming Tian
Publikováno v:
Bulletin of Faculty of Physical Therapy, Vol 29, Iss 1, Pp 1-10 (2024)
Abstract Background In Bangladesh, the most prevalent musculoskeletal condition among office employees is considered as BlackBerry thumb (BBT). Alike official perspectives, our educational system was significantly regulating with the digital interfac
Externí odkaz:
https://doaj.org/article/1069fa6fa8dd4b8e8318166cf9d1c131
Publikováno v:
eLife, Vol 9 (2020)
The eukaryotic replisome assembles around the CMG helicase, which stably associates with DNA replication forks throughout elongation. When replication terminates, CMG is ubiquitylated on its Mcm7 subunit and disassembled by the Cdc48/p97 ATPase. Unti
Externí odkaz:
https://doaj.org/article/6c8161f617dc48f6bb5652e3e06dc23f
Autor:
Ye Hong, Remi Sonneville, Bin Wang, Viktor Scheidt, Bettina Meier, Alexander Woglar, Sarah Demetriou, Karim Labib, Verena Jantsch, Anton Gartner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Chromosome segregation and genome maintenance require the removal of DNA bridges that link chromosomes just before cells divide. Here the authors show that the LEM-3/Ankle1 nuclease processes DNA bridges before cells divide and define a previously un
Externí odkaz:
https://doaj.org/article/1e006c13ac23401faf2de36c69fca25c
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3033-3042 (2017)
Disassembly of the Cdc45-MCM-GINS (CMG) DNA helicase is the key regulated step during DNA replication termination in eukaryotes, involving ubiquitylation of the Mcm7 helicase subunit, leading to a disassembly process that requires the Cdc48 “segreg
Externí odkaz:
https://doaj.org/article/321274dabc7841daabeab2f9a61d2f35
Publikováno v:
eLife, Vol 8 (2019)
The faithful segregation of eukaryotic chromosomes in mitosis requires that the genome be duplicated completely prior to anaphase. However, cells with large genomes sometimes fail to complete replication during interphase and instead enter mitosis wi
Externí odkaz:
https://doaj.org/article/7a4bbbba579a45c4a2b6bfe82441f165
Autor:
Ye Hong, Maria Velkova, Nicola Silva, Marlène Jagut, Viktor Scheidt, Karim Labib, Verena Jantsch, Anton Gartner
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007453 (2018)
Homologous recombination is essential for crossover (CO) formation and accurate chromosome segregation during meiosis. It is of considerable importance to work out how recombination intermediates are processed, leading to CO and non-crossover (NCO) o
Externí odkaz:
https://doaj.org/article/64caa845417046a49b92c42a3a4e1320
Autor:
Tom D Deegan, Karim Labib, Giuseppe Cannone, Michael Jenkyn-Bedford, Joseph T.P. Yeeles, Yasemin Baris, Morgan L. Jones
Publikováno v:
Nature
Jenkyn-Bedford, M, Jones, M L, Baris, Y, Labib, K P M, Cannone, G, Yeeles, J T P & Deegan, T D 2021, ' A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes ', Nature . https://doi.org/10.1038/s41586-021-04145-3
Jenkyn-Bedford, M, Jones, M L, Baris, Y, Labib, K P M, Cannone, G, Yeeles, J T P & Deegan, T D 2021, ' A Conserved Mechanism for Regulating Replisome Disassembly in Eukaryotes ', Nature . https://doi.org/10.1038/s41586-021-04145-3
Replisome disassembly is the final step of eukaryotic DNA replication and is triggered by ubiquitylation of the CDC45–MCM–GINS (CMG) replicative helicase1–3. Despite being driven by evolutionarily diverse E3 ubiquitin ligases in different eukar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3762dde9c47e717fe2f32dd809798c47
https://doi.org/10.1038/s41586-021-04145-3
https://doi.org/10.1038/s41586-021-04145-3
Publikováno v:
Cell Reports, Vol 12, Iss 3, Pp 405-417 (2015)
During cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates. In most tissues, S phase and mitosis are separated by defined G1 and G2 gap phases, but early embryo
Externí odkaz:
https://doaj.org/article/fe58d21069a64a398a313e57cc81a872
Autor:
Berta Canal, Allison W. McClure, Joseph F. Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P. Bertolin, Jennifer C. Milligan, Souradeep Basu, Lucy S. Drury, Tom Deegan, Ryo Fujisawa, Emma L. Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F.X Diffley
Publikováno v:
Biochemical Journal
SummarySARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great pressure, and there is urgent need for effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fecacd84c888a43831e441cefbc679e
http://europepmc.org/articles/PMC8286829
http://europepmc.org/articles/PMC8286829
Autor:
Kang Wei Tan, Emma L. Roberts, Tiffany Mak, Lucy S. Drury, Souradeep Basu, Berta Canal, Michael Howell, Joseph F. Curran, Florian Weissmann, Karim Labib, Tom D Deegan, John F.X. Diffley, Allison W McClure, Ryo Fujisawa, Mary Wu, Victoria H. Cowling, Rachel Ulferts, Clovis Basier, Rupert Beale, Theresa U. Zeisner, Chew Theng Lim
Publikováno v:
Biochemical Journal
The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74acc162b19fe84f371a9c793c9d9297
http://europepmc.org/articles/PMC8286817
http://europepmc.org/articles/PMC8286817