Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kari Nousiainen"'
Publikováno v:
International Archives of Occupational and Environmental Health. 96:577-586
Objective Despite the continuous development of occupational safety, the prevalence of work-related head injuries is excessive. To promote prevention, we conducted a study evaluating the risks and pathways that precede head injuries in different econ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97eacd9d517f1f6385e4543f0fda20e
https://doi.org/10.1007/s00420-022-01950-9
https://doi.org/10.1007/s00420-022-01950-9
Autor:
Subhash K. Tripathi, Zhi Chen, Antti Larjo, Kartiek Kanduri, Kari Nousiainen, Tarmo Äijo, Isis Ricaño-Ponce, Barbara Hrdlickova, Soile Tuomela, Essi Laajala, Verna Salo, Vinod Kumar, Cisca Wijmenga, Harri Lähdesmäki, Riitta Lahesmaa
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1888-1901 (2017)
The development of therapeutic strategies to combat immune-associated diseases requires the molecular mechanisms of human Th17 cell differentiation to be fully identified and understood. To investigate transcriptional control of Th17 cell differentia
Externí odkaz:
https://doaj.org/article/d673990638a54d0f83990621f297efa2
Autor:
Lauri A. Aaltonen, Jussi Taipale, Auli Karhu, Rainer Lehtonen, Diego Arango, Torben Orntoft, Heikki Järvinen, Jukka-Pekka Mecklin, Kyösti Nuorva, Sampsa Hautaniemi, Kari Nousiainen, Juha Saharinen, Virpi Launonen, Teemu Kivioja, Heli J. Lehtonen, Iina Niittymäki, Mia Biström, Sari Tuupanen, Mikko Turunen, Heli Sammalkorpi, Mikael Björklund, Pia Alhopuro
Supplementary Figures S1-S3 and Supplementary Tables S1-S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b56a8a1ee8a99e34fff4bda299fe61
https://doi.org/10.1158/1541-7786.22518903.v1
https://doi.org/10.1158/1541-7786.22518903.v1
Autor:
Lauri A. Aaltonen, Jussi Taipale, Auli Karhu, Rainer Lehtonen, Diego Arango, Torben Orntoft, Heikki Järvinen, Jukka-Pekka Mecklin, Kyösti Nuorva, Sampsa Hautaniemi, Kari Nousiainen, Juha Saharinen, Virpi Launonen, Teemu Kivioja, Heli J. Lehtonen, Iina Niittymäki, Mia Biström, Sari Tuupanen, Mikko Turunen, Heli Sammalkorpi, Mikael Björklund, Pia Alhopuro
The circadian clock regulates daily variations in physiologic processes. CLOCK acts as a regulator in the circadian apparatus controlling the expression of other clock genes, including PER1. Clock genes have been implicated in cancer-related function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5081e44f1390e7f3dd29c5b69e3068
https://doi.org/10.1158/1541-7786.c.6542175
https://doi.org/10.1158/1541-7786.c.6542175
Autor:
Imran Mohammad, Kari Nousiainen, Santosh D Bhosale, Inna Starskaia, Robert Moulder, Anne Rokka, Fang Cheng, Ponnuswamy Mohanasundaram, John E Eriksson, David R Goodlett, Harri Lähdesmäki, Zhi Chen
Publikováno v:
PLoS Biology, Vol 16, Iss 5, p e2004194 (2018)
The transcriptional network and protein regulators that govern T helper 17 (Th17) cell differentiation have been studied extensively using advanced genomic approaches. For a better understanding of these biological processes, we have moved a step for
Externí odkaz:
https://doaj.org/article/e1a5c6970d6d474f9a9a6eac85bb118b
Publikováno v:
Rapid-Fire Presentations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673aa46c090358b28a50a0c88cf21528
https://doi.org/10.1136/oem-2021-epi.366
https://doi.org/10.1136/oem-2021-epi.366
Publikováno v:
Algorithms for Computational Biology ISBN: 9783030181734
AlCoB
AlCoB
Cell differentiation and development are for a great part steered by cell type specific enhancers. Transcription factor (TF) binding to an enhancer together with DNA looping result in transcription initiation. In addition to binding motifs for TFs, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b8b853f1cc26bef4568ab18a216a11
https://doi.org/10.1007/978-3-030-18174-1_14
https://doi.org/10.1007/978-3-030-18174-1_14
Publikováno v:
Bioinformatics
Motivation: Mechanistic models based on ordinary differential equations provide powerful and accurate means to describe the dynamics of molecular machinery which orchestrates gene regulation. When combined with appropriate statistical techniques, mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53369f0fe2e837a156d53a0aaed0789e
http://juuli.fi/Record/0274695816
http://juuli.fi/Record/0274695816
Autor:
Kari Nousiainen, Cisca Wijmenga, Vinod Kumar, Harri Lähdesmäki, Kartiek Kanduri, Isis Ricaño-Ponce, Riitta Lahesmaa
Publikováno v:
Bioinformatics, 34, 4112-4114
Bioinformatics
Bioinformatics, 34, 23, pp. 4112-4114
Bioinformatics (Oxford, England), 34(23), 4112-4114. Oxford University Press
Bioinformatics
Bioinformatics, 34, 23, pp. 4112-4114
Bioinformatics (Oxford, England), 34(23), 4112-4114. Oxford University Press
Motivation Co-localization of trait associated SNPs for specific transcription-factor binding sites or regulatory regions in the genome can yield profound insight into underlying causal mechanisms. Analysis is complicated because the truly causal SNP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2aa21ccedfc365f1f3cdd144c4f0ca5
http://hdl.handle.net/2066/199422
http://hdl.handle.net/2066/199422
Autor:
Sampsa Hautaniemi, Britta Fritzsche, Marco Gerling, Gert Auer, Jens K. Habermann, Nils Homann, Stefan Krüger, Kari Nousiainen, Uwe J. Roblick, Thomas Ried, Hans-Peter Bruch
Publikováno v:
Inflamm Bowel Dis
Background Malignant transformation in ulcerative colitis (UC) is associated with pronounced chromosomal instability, reflected by aneuploidy. Although aneuploidy can precede primary cancer diagnosis in UC for more than a decade, little is known of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d90e61629cead5827a5669cc08fccf4
https://doi.org/10.1097/mib.0b013e31827eeaa4
https://doi.org/10.1097/mib.0b013e31827eeaa4