Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kari Martyniak"'
Autor:
Paul Stolarov, Jonathan de Vries, Sean Stapleton, Lauren Morris, Kari Martyniak, Thomas J. Kean
Publikováno v:
Materials, Vol 17, Iss 5, p 1218 (2024)
Background: Complex bone defects are challenging to treat. Autografting is the gold standard for regenerating bone defects; however, its limitations include donor-site morbidity and increased surgical complexity. Advancements in 3D bioprinting (3DBP)
Externí odkaz:
https://doaj.org/article/fb16ee1369244755b2e51d7df7423609
Autor:
Kari Martyniak, Sean Kennedy, Makan Karimzadeh, Maria A. Cruz, Oju Jeon, Eben Alsberg, Thomas J. Kean
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 997 (2023)
The surface zone of articular cartilage is the first area impacted by cartilage defects, commonly resulting in osteoarthritis. Chondrocytes in the surface zone of articular cartilage synthesize and secrete lubricin, a proteoglycan that functions as a
Externí odkaz:
https://doaj.org/article/d4e36ed470bf4501acb883607f56beff
Autor:
Rachel L. Pan, Kari Martyniak, Makan Karimzadeh, David G. Gelikman, Jonathan DeVries, Kelly Sutter, Melanie Coathup, Mehdi Razavi, Rajendra Sawh‐Martinez, Thomas J. Kean
Publikováno v:
Journal of Experimental Orthopaedics, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Background Joint degeneration and large or complex bone defects are a significant source of morbidity and diminished quality of life worldwide. There is an unmet need for a functional implant with near‐native biomechanical properties. The
Externí odkaz:
https://doaj.org/article/8d79c8a0609042bca3e2f52fb9435d58
Autor:
Mahmoud Omer, Christopher Ngo, Hessein Ali, Nina Orlovskaya, Vee San Cheong, Amelia Ballesteros, Michael Tyrel Garner, Austin Wynn, Kari Martyniak, Fei Wei, Boyce E. Collins, Sergey N. Yarmolenko, Jackson Asiatico, Michael Kinzel, Ranajay Ghosh, Teerin Meckmongkol, Ashley Calder, Naima Dahir, Timothy A. Gilbertson, Jagannathan Sankar, Melanie Coathup
Publikováno v:
Nutrients, Vol 15, Iss 5, p 1209 (2023)
Few studies have investigated the effect of a monosaturated diet high in ω-9 on osteoporosis. We hypothesized that omega-9 (ω-9) protects ovariectomized (OVX) mice from a decline in bone microarchitecture, tissue loss, and mechanical strength, ther
Externí odkaz:
https://doaj.org/article/33b4ed2116b342df85b81b860ca6d86a
Autor:
Mahmoud Omer, Hessein Ali, Nina Orlovskaya, Amelia Ballesteros, Vee San Cheong, Kari Martyniak, Fei Wei, Boyce E. Collins, Sergey N. Yarmolenko, Jackson Asiatico, Michael Kinzel, Christopher Ngo, Jagannathan Sankar, Ashley Calder, Timothy Gilbertson, Teerin Meckmongkol, Ranajay Ghosh, Melanie Coathup
Publikováno v:
Nutrients, Vol 14, Iss 15, p 3165 (2022)
The influence of diet on the development of osteoporosis is significant and not fully understood. This study investigated the effect of diets of varying lipid profiles and ω-3, ω-6 and ω-9 composition on the structural and mechanical properties of
Externí odkaz:
https://doaj.org/article/9f80ab7be43e48eb9fce99c0230b19e3
Autor:
Lukasz Gmerek, Kari Martyniak, Karolina Horbacka, Piotr Krokowicz, Wojciech Scierski, Pawel Golusinski, Wojciech Golusinski, Augusto Schneider, Michal M Masternak
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0222013 (2019)
Colorectal cancer is recognized as the fourth leading cause of cancer-related deaths worldwide. Thus, there is ongoing search for potential new biomarkers allowing quicker and less invasive detection of the disease and prediction of the treatment out
Externí odkaz:
https://doaj.org/article/8b2ec5dd316540f9b95056cc384beb7b
Autor:
Kari Martyniak, Alesia Lokshina, Maria A. Cruz, Makan Karimzadeh, Rachel Kemp, Thomas J. Kean
Publikováno v:
Acta Biomaterialia. 152:221-234
Gelatin methacrylate (GelMA) and hyaluronic acid methacrylate (HAMA) are frequently used biomaterials for 3D bioprinting, with individual well-established material characteristics. To identify an ideal combination of GelMA and HAMA for chondrogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f52dcb9665cde736f8b96d524b21d9
https://doi.org/10.1016/j.actbio.2022.08.058
https://doi.org/10.1016/j.actbio.2022.08.058
Osteoarthritis is a significant and growing problem with no disease modifying drugs in the clinic. Current screening platforms typically use 2D culture, immortalized or non-human cells in a hyperoxic environment. To challenge this paradigm and identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90fc94c3015f70acf18f2c987ebc90cb
https://doi.org/10.1101/2023.03.10.532073
https://doi.org/10.1101/2023.03.10.532073
Autor:
Michal M. Masternak, Kari Martyniak
Publikováno v:
Experimental Gerontology. 94:59-63
Adipose tissue represents complex endocrine organ containing several different cellular populations including adipocytes, pre-adipocytes, mesenchymal stem cells, macrophages and lymphocytes. It is well establishing that these populations are not stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32af7e68c2c74bdf598c97258415491f
https://doi.org/10.1016/j.exger.2016.12.007
https://doi.org/10.1016/j.exger.2016.12.007
Autor:
Amelia Ballesteros, Fei Wei, Melanie J. Coathup, Timothy A. Gilbertson, Nina Orlovskaya, Kari Martyniak, Ashley Calder, Teerin Meckmongkol
Publikováno v:
Bone. 143:115736
Age-related bone loss is inevitable in both men and women and there will soon be more people of extreme old age than ever before. Osteoporosis is a common chronic disease and as the proportion of older people, rate of obesity and the length of life i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686ce8308f038f740b6483822d27c4d
https://doi.org/10.1016/j.bone.2020.115736
https://doi.org/10.1016/j.bone.2020.115736