Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kari Manni"'
Autor:
Kerri Amaral, Evelin Fischer, Kari Manni, Georg Neckermann, Robert Pecanka, Donghui Yu, Julie Goldovitz, JoAnn Dzink-Fox, Neil S. Ryder, Colin Osborne
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:3777-3781
LBM415 is an antibacterial agent belonging to the peptide deformylase inhibitor class of compounds. It has previously been shown to demonstrate good activity in vitro against a range of pathogens. In this study, the in vivo efficacy of LBM415 was eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb9c42c4644036698a702d82c494b43
https://doi.org/10.1128/aac.00026-09
https://doi.org/10.1128/aac.00026-09
Autor:
JoAnn Dzink-Fox, Deborah Palestrant, Akash Jain, Bushell Simon, Meena Sachdeva, Jason T. Brewer, Stacey Tiamfook, Maria-Dawn Lilly, Eric Gangl, Lewis Whitehead, Alejandra Raimondi, Srijan Ranjitkar, Michael A. Patane, Matthew J. LaMarche, Steve Mullin, Elin M. Rann, Lac Lee, Georg Neckermann, Kari Manni, Jennifer A. Leeds, Janetta Dewhurst, Jian Shao, Colin Osborne, Donghui Yu, Gejing Deng
Publikováno v:
Antimicrobial agents and chemotherapy. 55(11)
Recently, we identified aminothiazole derivatives of GE2270 A. These novel semisynthetic congeners, like GE2270 A, target the essential bacterial protein elongation factor Tu (EF-Tu). Medicinal chemistry optimization of lead molecules led to the iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacc6276d0efb008e92187e85d6546f5
https://pubmed.ncbi.nlm.nih.gov/21825297
https://pubmed.ncbi.nlm.nih.gov/21825297