Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kari M. Mattila"'
Autor:
Lyzel S Elias-Sonnenschein, Seppo Helisalmi, Teemu Natunen, Anette Hall, Teemu Paajanen, Sanna-Kaisa Herukka, Marjo Laitinen, Anne M Remes, Anne M Koivisto, Kari M Mattila, Terho Lehtimäki, Frans R J Verhey, Pieter Jelle Visser, Hilkka Soininen, Mikko Hiltunen
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59676 (2013)
OBJECTIVES: To understand the relation between risk genes for Alzheimer's disease (AD) and their influence on biomarkers for AD, we examined the association of AD in the Finnish cohort with single nucleotide polymorphisms (SNPs) from top AlzGene loci
Externí odkaz:
https://doaj.org/article/c9f56374400345e98bb710f9782bb034
Autor:
Mitja I. Kurki, Anne M. Remes, Anette Hall, Henna Martiskainen, Ville Leinonen, Terho Lehtimäki, Mikko Hiltunen, Anne M. Koivisto, Kari M. Mattila, Hilkka Soininen, Timo Sarajärvi, Marjo Laitinen, Seppo Helisalmi, Petra Mäkinen, Teemu Natunen, Jayashree Viswanathan, Kaisa M.A. Kurkinen, Sanna-Kaisa Herukka, Annakaisa Haapasalo, Jaakko Huovinen
Publikováno v:
Journal of Alzheimer's Disease. 43:565-573
BACKGROUND Several risk loci for Alzheimer's disease (AD) have been identified during recent years in large-scale genome-wide association studies. However, little is known about the mechanisms by which these loci influence AD pathogenesis. OBJECTIVE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb52bb79515c9cabfab4d4dfcb8a0ff
https://doi.org/10.3233/jad-140777
https://doi.org/10.3233/jad-140777
Autor:
Kari M. Mattila, Esa Leinonen, Martti Huuhka, Olli Kampman, Kaija Huuhka, Sami Anttila, Terho Lehtimäki, Riikka Rontu, Mikko Hurme
Publikováno v:
Neuroscience Letters. 437:25-28
We studied the association between RGS4 (rs951436) polymorphism and treatment response in electroconvulsive therapy (ECT) as well as risk of treatment-resistant depression. The study sample consisted of 119 patients with major depressive disorder (MD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32fbcd8d966e6bb6518fab545ac212d
https://doi.org/10.1016/j.neulet.2008.03.065
https://doi.org/10.1016/j.neulet.2008.03.065
Autor:
Riikka Rontu, Mikko Hurme, Heikki Katila, Olli Kampman, Kari M. Mattila, Ari Illi, Terho Lehtimäki, Esa Leinonen, Kari Hänninen, Sami Anttila
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 22:211-215
Catechol-O-methyltransferase (COMT) gene has been investigated as a possible candidate gene in schizophrenia. The most studied polymorphism has been the functional val108/158met polymorphism of this COMT gene. There is also some evidence that this po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf30a46753ddcfbc77827a5ed5ccca2b
https://doi.org/10.1002/hup.841
https://doi.org/10.1002/hup.841
Autor:
Esa Leinonen, Martti Huuhka, Riikka Rontu, Sami Anttila, Terho Lehtimäki, Kaija Huuhka, Kari M. Mattila
Publikováno v:
Journal of Neural Transmission. 114:461-468
We studied the association between tryptophan hydroxylase 1 (TPH1) A218C and G-protein beta-3 subunit (GNB3) C825T polymorphisms and treatment response in electroconvulsive therapy (ECT). The sample consisted of 119 patients with major depressive dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df74c6d4e5f760c4b56f75e610957953
https://doi.org/10.1007/s00702-006-0583-6
https://doi.org/10.1007/s00702-006-0583-6
Publikováno v:
Neurochemical Research. 30:1501-1510
The etiopathogenesis of Alzheimer's disease (AD) is still unclear, although clinical diagnostic criteria exist and the neuropathology of AD has been studied in great detail during the last 20 years. The present study addresses certain problems in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ff9ecddf8e134956334cc46abec305
https://doi.org/10.1007/s11064-005-8827-7
https://doi.org/10.1007/s11064-005-8827-7
Autor:
Kari M. Mattila, Esa Leinonen, Riikka Rontu, Kaija Huuhka, Heini Huhtala, Terho Lehtimäki, Martti Huuhka, Sami Anttila
Publikováno v:
The Journal of ECT. 21:7-11
The apolipoprotein E (APOE) polymorphism is associated with neurodegenerative diseases. Its role regarding psychiatric disorders is controversial. It has been suggested to affect antidepressant treatment response and response to electroconvulsive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba599de72ef321443aff077b7e97d9e
https://doi.org/10.1097/01.yct.0000153210.25362.ea
https://doi.org/10.1097/01.yct.0000153210.25362.ea
Autor:
Sami Anttila, Olli Kampman, Kari M. Mattila, Ari Illi, Esa Leinonen, Terho Lehtimäki, Riikka Rontu
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience. 255:279-283
The study population comprised 94 Finnish patients with DSM-IV diagnosis of schizophrenia. The patients were placed into two subgroups according to medication response to conventional neuroleptics. The aim of the study was to examine the frequency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35706d68586b3d60ded32b394688b2e
https://doi.org/10.1007/s00406-004-0560-8
https://doi.org/10.1007/s00406-004-0560-8
Autor:
Olli Kampman, Terho Lehtimäki, Ari Illi, Esa Leinonen, Kari M. Mattila, Riikka Rontu, Sami Anttila, Marika Saarela
Publikováno v:
NeuroReport. 15:2517-2520
Neuregulin 1 is involved both in neurodevelopment and neurotransmitter mechanisms in the brain. There is evidence of an association between neuregulin 1 genotype and schizophrenia. We compared neuregulin 1 genotypes in patients with schizophrenia (n=
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4e5176f7cb5eae05239b429d00d755
https://doi.org/10.1097/00001756-200411150-00017
https://doi.org/10.1097/00001756-200411150-00017
Autor:
Matias Röyttä, Kari M. Mattila, Marika Saarela, Juha O. Rinne, Marja Jylhä, Jukka-Pekka Ahonen, Antti Hervonen, Terho Lehtimäki
Publikováno v:
Neuroscience Letters. 367:336-339
Polymorphisms affecting the expression of matrix metalloproteinases (MMPs), i.e. proteolytic enzymes that degrade intercellular material, have been found at position -1607 (1G/2G) in MMP1 and at -1171 (5A/6A) in MMP3. Interestingly, elevated levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40475211a681845431b8d5c139d7a418
https://doi.org/10.1016/j.neulet.2004.06.027
https://doi.org/10.1016/j.neulet.2004.06.027