Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kari L Allen"'
Autor:
Robert A Kaiser, Daniel F Carlson, Kari L Allen, Dennis A Webster, Caitlin J VanLith, Clara T Nicolas, Lori G Hillin, Yue Yu, Catherine W Kaiser, William R Wahoff, Raymond D Hickey, Adrienne L Watson, Shelley R Winn, Beat Thöny, Douglas R Kern, Cary O Harding, Joseph B Lillegard
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245831 (2021)
Phenylketonuria (PKU) is a metabolic disorder whereby phenylalanine metabolism is deficient due to allelic variations in the gene for phenylalanine hydroxylase (PAH). There is no cure for PKU other than orthotopic liver transplantation, and the stand
Externí odkaz:
https://doaj.org/article/f3e73823f1454455a713448bd5ccf3f7
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118732 (2015)
The correlation between diet and dental topography is of importance to paleontologists seeking to diagnose ecological adaptations in extinct taxa. Although the subject is well represented in the literature, few studies directly compare methods or eva
Externí odkaz:
https://doaj.org/article/b67c601c6b734448a9f8d64af1010bc4
Autor:
Clara T. Nicolas, Robert A. Kaiser, Raymond D. Hickey, Kari L. Allen, Zeji Du, Caitlin J. VanLith, Rebekah M. Guthman, Bruce Amiot, Lukkana Suksanpaisan, Bing Han, Maria Giovanna Francipane, Amin Cheikhi, Huailei Jiang, Aditya Bansal, Mukesh K. Pandey, Ishan Garg, Val Lowe, Aditya Bhagwate, Daniel O’Brien, Jean-Pierre A. Kocher, Timothy R. DeGrado, Scott L. Nyberg, Eric Lagasse, Joseph B. Lillegard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 738-750 (2020)
The effectiveness of cell-based therapies to treat liver failure is often limited by the diseased liver environment. Here, we provide preclinical proof of concept for hepatocyte transplantation into lymph nodes as a cure for liver failure in a large-
Externí odkaz:
https://doaj.org/article/8ffcb39c8aed4257acfa76228d16a408
Autor:
Leigha M, Lynch, Kari L, Allen
Publikováno v:
Brain, Behavior and Evolution. 97:284-297
Carnivorans possess relatively large brains compared to most other mammalian clades. Factors like environmental complexity (Cognitive Buffer Hypothesis) and diet quality (Expensive-Tissue Hypothesis) have been proposed as mechanisms for encephalizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b857b3fca440bac30998f4c446c55a
https://doi.org/10.1159/000523787
https://doi.org/10.1159/000523787
Autor:
Michael Martinez, Nicholas D. Weber, William Cao, Lori G Hillin, Robert A. Kaiser, Anne Douar, Kari L. Allen, Joseph B. Lillegard, Caitlin J. VanLith, Rafael Aldabe, Laia Trigueros-Motos, Gloria González-Aseguinolaza
Publikováno v:
Journal of Inherited Metabolic Disease. 44:1369-1381
Phenylketonuria (PKU) is the most common inborn error of metabolism of the liver, and results from mutations of both alleles of the phenylalanine hydroxylase gene (PAH). As such, it is a suitable target for gene therapy via gene delivery with a recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23c76d8f40370a31f5d41f8847fe54e
https://doi.org/10.1002/jimd.12392
https://doi.org/10.1002/jimd.12392
Autor:
Jimmy H. Daruwalla, Amelia C. Van Handel, Kari L. Allen, Leigha M. Lynch, James P. Higgins, Mitchell A. Pet
Publikováno v:
Journal of Hand Surgery (European Volume). 46:1042-1048
Surgical options for advanced Kienböck’s disease include proximal row carpectomy or lunate reconstruction with a medial femoral trochlea osteochondral flap. This study compares morphology of the proximal capitate and the medial femoral trochlear s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd366860ddbdbeaf8f754bd4966ba63
https://doi.org/10.1177/17531934211031862
https://doi.org/10.1177/17531934211031862
Autor:
Bruce Amiot, Timothy R. DeGrado, Amin Cheikhi, Caitlin J. VanLith, Val J. Lowe, Aditya Bansal, Robert A. Kaiser, Mukesh K. Pandey, Daniel R. O'Brien, Zeji Du, Huailei Jiang, Raymond D. Hickey, Rebekah M. Guthman, Lukkana Suksanpaisan, Scott L. Nyberg, Jean Pierre A. Kocher, Aditya Bhagwate, Ishan Garg, Maria Giovanna Francipane, Eric Lagasse, Clara T. Nicolas, Joseph B. Lillegard, Bing Han, Kari L. Allen
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 738-750 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The effectiveness of cell-based therapies to treat liver failure is often limited by the diseased liver environment. Here, we provide preclinical proof of concept for hepatocyte transplantation into lymph nodes as a cure for liver failure in a large-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594a12ff39203dc0dfd7fad66b0d80a6
http://www.sciencedirect.com/science/article/pii/S2329050120301583
http://www.sciencedirect.com/science/article/pii/S2329050120301583
Autor:
Raymond D. Hickey, Kari L. Allen, Joseph B. Lillegard, Robert A. Kaiser, Zeji Du, Jennifer Anne Chilton, Clara T. Nicolas
Publikováno v:
Human Gene Therapy Clinical Development. 30:57-66
General safety and toxicology assessments supporting in vivo lentiviral vector-based therapeutic development are sparse. We have previously demonstrated the efficacy of a lentiviral vector expressi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b56ebf39e4a7c6cadbc82986f5cd63bb
https://doi.org/10.1089/humc.2018.249
https://doi.org/10.1089/humc.2018.249
Autor:
Kari L. Allen, Jennifer Anne Chilton, Clara T. Nicolas, Rebekah M. Guthman, Robert A. Kaiser, Raymond D. Hickey, Joseph B. Lillegard, Yuanhang Liu, Zachariah P. Tritz, Scott L. Nyberg, Caitlin J. VanLith
Publikováno v:
Hepatology Communications
Ex vivo CRISPR/Cas9‐mediated gene editing in hepatocytes using homology‐directed repair (HDR) is a potential alternative curative therapy to organ transplantation for metabolic liver disease. However, a major limitation of this approach in quiesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a82014ce1dc99215656e9ef8441660
https://doi.org/10.1002/hep4.1315
https://doi.org/10.1002/hep4.1315
Autor:
Joseph B. Lillegard, Aditya Bhagwate, Lori G Hillin, Daniel R. O'Brien, Kari L. Allen, William Cao, Zeji Du, Rebekah M. Guthman, Stephen J. Russell, Jean-Pierre A. Kocher, Robert A. Kaiser, Raymond D. Hickey, Clara T. Nicolas, Caitlin J. VanLith
Conventional therapy for hereditary tyrosinemia type-1 (HT1) with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) delays and in some cases fails to prevent disease progression to liver fibrosis, liver failure, and activation of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff98a181e36e804c94ca3cb805d8d43
https://doi.org/10.1101/2021.01.02.425079
https://doi.org/10.1101/2021.01.02.425079
