Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Kari K. Alitalo"'
Autor:
Ligia Simoes Braga Boisserand, Jean Bouchart, Luiz Henrique Medeiros Geraldo, Seyoung Lee, Basavaraju Sanganahalli Ganganna, Maxime Parent, Shenqi Zhang, Yuechuan Xue, Mario Skarica, Justine Guegan, Mingfeng Li, Xiodan Liu, Mathilde Poulet, Michael Askanase, Artem Osherov, Myriam Spajer, Maarie-Renee El Kamouh, Anne Eichmann, Kari K Alitalo, Jianbing Zhou, Nenad Sestan, Lauren Sansing, Helene Benveniste, Fahmeed Hyder, jean-leon thomas
Publikováno v:
bioRxiv
Meningeal lymphatic vessels promote tissue clearance and immune surveillance in the central nervous system (CNS). Vascular endothelium growth factor-C (VEGF-C) is essential for meningeal lymphatic development and maintenance and has therapeutic poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80764d2a6ec0260a1b1f04d8eb2fb4bd
https://europepmc.org/articles/PMC10312491/
https://europepmc.org/articles/PMC10312491/
Autor:
Federico Innocenti, Kari K. Alitalo, Nancy Klauber-DeMore, Yuri K. Peterson, Carol E. Peña, Eleanor Hilliard, Amy S. Etheridge, Dylan M. Glubb, Veli-Matti Leppänen, Andrew D. Skol, Daniel J. Crona
Molecular markers of sorafenib efficacy in patients with metastatic renal cell carcinoma (mRCC) are not available. The purpose of this study was to discover genetic markers of survival in patients with mRCC treated with sorafenib. Germline variants f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39aded848b246b299f1aa3935abcab2e
https://doi.org/10.1158/0008-5472.c.6510876.v1
https://doi.org/10.1158/0008-5472.c.6510876.v1
Autor:
Federico Innocenti, Kari K. Alitalo, Nancy Klauber-DeMore, Yuri K. Peterson, Carol E. Peña, Eleanor Hilliard, Amy S. Etheridge, Dylan M. Glubb, Veli-Matti Leppänen, Andrew D. Skol, Daniel J. Crona
Genotyped genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea489788a0e11ae23909649e2b3d37f
https://doi.org/10.1158/0008-5472.22421274
https://doi.org/10.1158/0008-5472.22421274
Autor:
Federico Innocenti, Kari K. Alitalo, Nancy Klauber-DeMore, Yuri K. Peterson, Carol E. Peña, Eleanor Hilliard, Amy S. Etheridge, Dylan M. Glubb, Veli-Matti Leppänen, Andrew D. Skol, Daniel J. Crona
Expression of WT and T494A VEGFR-3 in HUVECs (A) and replication of phosphorylation experiments testing the effect of FLT4 rs307826 (A>G, T494A) on VEGFR-3 phosphorylation (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0641778c94baf07333459e92bfb3613e
https://doi.org/10.1158/0008-5472.22421286.v1
https://doi.org/10.1158/0008-5472.22421286.v1
Autor:
Federico Innocenti, Kari K. Alitalo, Nancy Klauber-DeMore, Yuri K. Peterson, Carol E. Peña, Eleanor Hilliard, Amy S. Etheridge, Dylan M. Glubb, Veli-Matti Leppänen, Andrew D. Skol, Daniel J. Crona
SNP selection criteria, imputation and bioinformatic analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083dbc4ae37a828e48613de46e170706
https://doi.org/10.1158/0008-5472.22421277.v1
https://doi.org/10.1158/0008-5472.22421277.v1
Autor:
Katri Mataleena Vaparanta, Anne Jokilammi, Ilkka Paatero, Johannes A.M. Merilahti, Juho Heliste, Karthik Amudhala Hemanthakumar, Riikka Kivelä, Kari K Alitalo, Pekka Taimen, Klaus Elenius
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e75af74b3b44998f39fb596c4c1c90
https://doi.org/10.15252/rc.2022754241
https://doi.org/10.15252/rc.2022754241
Autor:
Daniel J, Crona, Andrew D, Skol, Veli-Matti, Leppänen, Dylan M, Glubb, Amy S, Etheridge, Eleanor, Hilliard, Carol E, Peña, Yuri K, Peterson, Nancy, Klauber-DeMore, Kari K, Alitalo, Federico, Innocenti
Publikováno v:
Cancer research. 79(1)
Molecular markers of sorafenib efficacy in metastatic renal cell carcinoma (mRCC) patients are not available. The purpose of this study was to discover genetic markers of survival in mRCC patients treated with sorafenib. Germline variants from 56 gen
Autor:
Karaman S; Wihuri Research Institute, Helsinki, Finland.; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lehti S; Wihuri Research Institute, Helsinki, Finland.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Zhang C; Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden., Taskinen MR; Research Programs Unit, Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland., Käkelä R; Helsinki University Lipidomics Unit (HiLIPID), Helsinki Institute of Life Science (HiLIFE) and Biocenter Finland, Helsinki, Finland.; Molecular and Integrative Biosciences Research Program, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland., Mardinoglu A; Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden.; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK., Brorson H; Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden.; Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden.; Lund University Cancer Centre, Lund, Sweden.; Department of Health Sciences, Faculty of Medicine, Health & Human Sciences, Macquarie University, Sydney, New South Wales, Australia., Alitalo K; Wihuri Research Institute, Helsinki, Finland.; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Kivelä R; Wihuri Research Institute, Helsinki, Finland.; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.; Stem Cell and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Oct 31; Vol. 38 (20), pp. e70097.
Autor:
Roos-Mattila M; Department of Surgery, Helsinki University Hospital, Helsinki, Finland. matilda.roos-mattila@helsinki.fi.; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. matilda.roos-mattila@helsinki.fi.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland. matilda.roos-mattila@helsinki.fi., Kallio P; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Luck TJ; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Polso M; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Kumari R; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Mikkonen P; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Välimäki K; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Malmstedt M; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; ONCOSYS Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Ellonen P; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Pellinen T; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Heckman CA; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Mustonen H; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Puolakkainen PA; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Alitalo K; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Wihuri Research Institute, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland., Kallioniemi O; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland.; Science for Life Laboratory (SciLifeLab), Department of Oncology and Pathology, Karolinska Institutet, Solna, 17165, Sweden., Mirtti T; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; ONCOSYS Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, Department of Pathology, Helsinki University Hospital, Helsinki, Finland., Rannikko AS; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; ONCOSYS Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Pietiäinen VM; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland -FIMM, Helsinki Institute for Life Sciences -HiLIFE, University of Helsinki, Helsinki, Finland., Seppänen HE; Department of Surgery, Helsinki University Hospital, Helsinki, Finland.; Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.
Publikováno v:
Communications biology [Commun Biol] 2024 Oct 20; Vol. 7 (1), pp. 1355. Date of Electronic Publication: 2024 Oct 20.
Autor:
Keuters MH; Neuroscience Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki, 00014, Helsinki, Finland.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland., Antila S; Wihuri Research Institute and Translational Cancer Medicine Program, University of Helsinki, 00014, Helsinki, Finland., Immonen R; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland., Plotnikova L; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland., Wojciechowski S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland., Lehtonen S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland., Alitalo K; Wihuri Research Institute and Translational Cancer Medicine Program, University of Helsinki, 00014, Helsinki, Finland., Koistinaho J; Neuroscience Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki, 00014, Helsinki, Finland.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland.; Drug Research Program, Division of Pharmacology and Pharmacotherapy, University of Helsinki, 00014, Helsinki, Finland., Dhungana H; Neuroscience Center, Helsinki Institute of Life Science (HiLIFE), University of Helsinki, 00014, Helsinki, Finland. hiramani.dhungana@helsinki.fi.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210, Kuopio, Finland. hiramani.dhungana@helsinki.fi.
Publikováno v:
Translational stroke research [Transl Stroke Res] 2024 Jun 01. Date of Electronic Publication: 2024 Jun 01.