Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kari E. Wong"'
Autor:
Lauren Bernard, Jingsha Chen, Hyunju Kim, Kari E. Wong, Lyn M. Steffen, Bing Yu, Eric Boerwinkle, Andrew S. Levey, Morgan E. Grams, Eugene P. Rhee, Casey M. Rebholz
Publikováno v:
Kidney Medicine, Vol 6, Iss 4, Pp 100793- (2024)
Rationale & Objective: While urine excretion of nitrogen estimates the total protein intake, biomarkers of specific dietary protein sources have been sparsely studied. Using untargeted metabolomics, this study aimed to identify serum metabolomic mark
Externí odkaz:
https://doaj.org/article/01bb8b8d3d9e4e73ab2d5263f48df40a
Autor:
Elena V. Feofanova, Michael R. Brown, Taryn Alkis, Astrid M. Manuel, Xihao Li, Usman A. Tahir, Zilin Li, Kevin M. Mendez, Rachel S. Kelly, Qibin Qi, Han Chen, Martin G. Larson, Rozenn N. Lemaitre, Alanna C. Morrison, Charles Grieser, Kari E. Wong, Robert E. Gerszten, Zhongming Zhao, Jessica Lasky-Su, NHLBI Trans-Omics for Precision Medicine (TOPMed), Bing Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Circulating metabolite levels may reflect the state of the human organism in health and disease, however, the genetic architecture of metabolites is not fully understood. We have performed a whole-genome sequencing association analysis of bo
Externí odkaz:
https://doaj.org/article/fd8c3eb176234d4c8fc8bb86a09934a5
Autor:
Elena V. Feofanova, Michael R. Brown, Taryn Alkis, Astrid M. Manuel, Xihao Li, Usman A. Tahir, Zilin Li, Kevin M. Mendez, Rachel S. Kelly, Qibin Qi, Han Chen, Martin G. Larson, Rozenn N. Lemaitre, Alanna C. Morrison, Charles Grieser, Kari E. Wong, Robert E. Gerszten, Zhongming Zhao, Jessica Lasky-Su, NHLBI Trans-Omics for Precision Medicine (TOPMed), Bing Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/217e19f1355c4277b19b99402e542882
Autor:
James J. Beaudoin, Lara Clemens, Mark T. Miedel, Albert Gough, Fatima Zaidi, Priya Ramamoorthy, Kari E. Wong, Rangaprasad Sarangarajan, Christina Battista, Lisl K. M. Shoda, Scott Q. Siler, D. Lansing Taylor, Brett A. Howell, Lawrence A. Vernetti, Kyunghee Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9692 (2023)
Biologics address a range of unmet clinical needs, but the occurrence of biologics-induced liver injury remains a major challenge. Development of cimaglermin alfa (GGF2) was terminated due to transient elevations in serum aminotransferases and total
Externí odkaz:
https://doaj.org/article/cf333ce0b61346e283a0479af7d19b6d
Autor:
Michael D. West, Ching-Fang Chang, Dana Larocca, Jie Li, Jianjie Jiang, Pamela Sim, Ivan Labat, Karen B. Chapman, Kari E. Wong, James Nicoll, Michael J. Van Kanegan, Aubrey D. N. J. de Grey, Igor O. Nasonkin, Andreas Stahl, Hal Sternberg
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background The role of brown fat in non-shivering thermogenesis and the discovery of brown fat depots in adult humans has made it the subject of intense research interest. A renewable source of brown adipocyte (BA) progenitors would be highl
Externí odkaz:
https://doaj.org/article/5ca70c671b0b41928c0c812a5c75f811
Autor:
Kanita Salic, Eveline Gart, Florine Seidel, Lars Verschuren, Martien Caspers, Wim van Duyvenvoorde, Kari E. Wong, Jaap Keijer, Ivana Bobeldijk-Pastorova, Peter Y. Wielinga, Robert Kleemann
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4359 (2019)
Obesity characterized by adiposity and ectopic fat accumulation is associated with the development of non-alcoholic fatty liver disease (NAFLD). Treatments that stimulate lipid utilization may prevent the development of obesity and comorbidities. Thi
Externí odkaz:
https://doaj.org/article/75aae11a33d54f7dbdc55f833729a250
Autor:
Donghan Su, Jingsha Chen, Shutong Du, Hyunju Kim, Bing Yu, Kari E. Wong, Eric Boerwinkle, Casey M. Rebholz
Publikováno v:
Clinical Journal of the American Society of Nephrology. 18:327-336
Autor:
Yang, James J. Beaudoin, Lara Clemens, Mark T. Miedel, Albert Gough, Fatima Zaidi, Priya Ramamoorthy, Kari E. Wong, Rangaprasad Sarangarajan, Christina Battista, Lisl K. M. Shoda, Scott Q. Siler, D. Lansing Taylor, Brett A. Howell, Lawrence A. Vernetti, Kyunghee
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9692
Biologics address a range of unmet clinical needs, but the occurrence of biologics-induced liver injury remains a major challenge. Development of cimaglermin alfa (GGF2) was terminated due to transient elevations in serum aminotransferases and total
Autor:
Hyunju Kim, Lawrence J. Appel, Alice H. Lichtenstein, Kari E. Wong, Nilanjan Chatterjee, Eugene P. Rhee, Casey M. Rebholz
Publikováno v:
Hypertension.
BACKGROUND: The DASH (Dietary Approaches to Stop Hypertension) diets reduced blood pressure (BP) in the DASH and DASH-Sodium trials, but the underlying mechanisms are unclear. We identified metabolites associated with systolic BP or diastolic BP (DBP
Autor:
Hyunju Kim, Bing Yu, Xin Li, Kari E Wong, Eric Boerwinkle, Sara B Seidelmann, Andrew S Levey, Eugene P Rhee, Josef Coresh, Casey M Rebholz
Publikováno v:
The American Journal of Clinical Nutrition. 116:151-164
Greater adherence to plant-based diets is associated with a lower risk of incident chronic kidney disease (CKD). Metabolomics can help identify blood biomarkers of plant-based diets and enhance understanding of underlying mechanisms.Using untargeted