Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kari A. Herrington"'
Autor:
Kun Leng, Brendan Rooney, Frank McCarthy, Wenlong Xia, Indigo V. L. Rose, Sophie Bax, Marcus Chin, Saeed Fathi, Kari A. Herrington, Manuel Leonetti, Aimee Kao, Stephen P. J. Fancy, Joshua E. Elias, Martin Kampmann
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Astrocytes respond and contribute to neuroinflammation by adopting inflammatory reactive states. Although recent efforts have characterized the gene expression signatures associated with these reactive states, the cell biology underlying inf
Externí odkaz:
https://doaj.org/article/3362c7cd0c774b99bc1e41cc97a52ae6
Autor:
Franziska Haderk, Yu-Ting Chou, Lauren Cech, Celia Fernández-Méndez, Johnny Yu, Victor Olivas, Ismail M. Meraz, Dora Barbosa Rabago, D. Lucas Kerr, Carlos Gomez, David V. Allegakoen, Juan Guan, Khyati N. Shah, Kari A. Herrington, Oghenekevwe M. Gbenedio, Shigeki Nanjo, Mourad Majidi, Whitney Tamaki, Yashar K. Pourmoghadam, Julia K. Rotow, Caroline E. McCoach, Jonathan W. Riess, J. Silvio Gutkind, Tracy T. Tang, Leonard Post, Bo Huang, Pilar Santisteban, Hani Goodarzi, Sourav Bandyopadhyay, Calvin J. Kuo, Jeroen P. Roose, Wei Wu, Collin M. Blakely, Jack A. Roth, Trever G. Bivona
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Targeted therapy is effective in many tumor types including lung cancer, the leading cause of cancer mortality. Paradigm defining examples are targeted therapies directed against non-small cell lung cancer (NSCLC) subtypes with oncogenic alt
Externí odkaz:
https://doaj.org/article/be0a7eca3725431ab19bfe58739629b9
Autor:
J. Silvio Gutkind, Rachel A. O'Keefe, Jason F. Kreisberg, Jisoo Park, Dana J. Ramms, David Jimenez-Morales, Trey Ideker, Danielle L. Swaney, Helene Foussard, Fan Zheng, Michael J. McGregor, Jennifer R. Grandis, Kari A. Herrington, Natalia Jura, Yusuke Goto, Nan Jin, Mehdi Bouhaddou, Yan Zeng, Kyumin Kim, Margaret Soucheray, Daniel Johnson, Zhiyong Wang, Nevan J. Krogan, Min-Kyu Kim, John Von Dollen, Kirsten Obernier, Neil E. Bhola, Nathan K. VanLandingham
Publikováno v:
Science (New York, N.Y.), vol 374, iss 6563
Science
Science
Mapping protein interactions driving cancer Cancer is a genetic disease, and much cancer research is focused on identifying carcinogenic mutations and determining how they relate to disease progression. Three papers demonstrate how mutations are proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a275fcfba104564e2a5218ab9c04ad
https://doi.org/10.1126/science.abf2911
https://doi.org/10.1126/science.abf2911
Autor:
Min-Kyu Kim, Jing Chen, Fan Zheng, Keiichiro Ono, Sophie Liu, Beril Tutuncuoglu, John J. Lee, Rudolf T. Pillich, Brent M. Kuenzi, Danielle L. Swaney, Jason F. Kreisberg, J. Silvio Gutkind, Erica Silva, Nicholas Wilson, Katherine Licon, Kari A. Herrington, Stephanie I. Fraley, Nevan J. Krogan, Dexter Pratt, Marcus R. Kelly, Christopher Churas, Michael Chen, Kai Tao, Jisoo Park, Xiaolin Nan, Dana J. Ramms, Anton Kratz, Trey Ideker, Marissa L. Heintschel, Michael Ku Yu, Helene Foussard, Devin Patel
Publikováno v:
Science (New York, N.Y.), vol 374, iss 6563
Science
Science
Mapping protein interactions driving cancer Cancer is a genetic disease, and much cancer research is focused on identifying carcinogenic mutations and determining how they relate to disease progression. Three papers demonstrate how mutations are proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bdd61e6a00d9bd25a0a7555abffde9
https://escholarship.org/uc/item/9839w2n4
https://escholarship.org/uc/item/9839w2n4
Autor:
Danielle L. Swaney, Kuei Ho Chen, Alan Ashworth, Morgan E. Diolaiti, Trey Ideker, Fan Zheng, Bing Xia, Kari A. Herrington, Beril Tutuncuoglu, Michael J. McGregor, John D. Gordan, Min-Kyu Kim, Mehdi Bouhaddou, Denise P. Muñoz, Denise M. Wolf, Erica Stevenson, Nevan J. Krogan, Margaret Soucheray, Tzeh Keong Foo, Patrick O’Leary, Ajda Rojc, Maya Modak, Kyumin Kim, Laura van 't Veer, Jean-Philippe Coppe, Jason F. Kreisberg, Jisoo Park, Dominique C. Mitchell
Publikováno v:
Science
Science (New York, N.Y.), vol 374, iss 6563
Science (New York, N.Y.), vol 374, iss 6563
Mapping protein interactions driving cancer Cancer is a genetic disease, and much cancer research is focused on identifying carcinogenic mutations and determining how they relate to disease progression. Three papers demonstrate how mutations are proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375ba5ac99a6a028e92c535730897988
https://europepmc.org/articles/PMC9040556/
https://europepmc.org/articles/PMC9040556/
Autor:
Manuel D. Leonetti, Saeed Fathi, Aimee W. Kao, Kari A. Herrington, Sophie Bax, Martin Kampmann, Kun Leng, Marcus Y. Chin, Joshua E. Elias, Frank McCarthy, Indigo V.L. Rose, Brendan Rooney
Inflammatory reactive astrocytes lose homeostatic functions and can be neurotoxic, potentially contributing to neurodegenerative diseases. However, the underlying cell biological mechanisms are not fully understood. Here, we demonstrate that lysosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf62582038ac0c543128bc3b8140882f
https://doi.org/10.1101/2021.09.11.459904
https://doi.org/10.1101/2021.09.11.459904
Autor:
Ellen C. O’Shaughnessy, Michelle A. Digman, Klaus M. Hahn, Enrico Gratton, Andrew L. Trinh, Kari A. Herrington, Christine Sütterlin, Carolyn Dang
Publikováno v:
Molecular Biology of the Cell
A Cdc42 biosensor and the phasor approach to FLIM-FRET are used to determine Cdc42 activity at specific subcellular locations, revealing new regulatory principles and functions of this small GTPase.
The ability of the small GTPase Cdc42 to regul
The ability of the small GTPase Cdc42 to regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e06fbf35fcda6aa2b26f215e60bc5d
https://pubmed.ncbi.nlm.nih.gov/28539409
https://pubmed.ncbi.nlm.nih.gov/28539409