Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Karen Yeow"'
Autor:
Ulrich J. M. Mey, Felicitas Hitz, Andreas Lohri, Stefanie Pederiva, Christian Taverna, Alexander Tzankov, Oliver Meier, Karen Yeow, Christoph Renner
Publikováno v:
Swiss Medical Weekly, Vol 142, Iss 0506 (2012)
Diffuse large B-cell lymphoma (DLBCL) is the most frequently-occurring type of malignant lymphoma in the Western world. It has an aggressive natural history, with a median survival of less than one year if left untreated. Immunochemotherapy regimens,
Externí odkaz:
https://doaj.org/article/60c2c513282e46599040739cecb8864b
Autor:
Alexander Scheer, Paul Lang, Pascale Gaillard, Jean-Pierre Gotteland, Laurence Novo-Perez, Patrick Page, Karen Yeow
Publikováno v:
ASSAY and Drug Development Technologies. 4:451-460
Glycogen synthase kinase-3 (GSK3) is a serine-threonine protein kinase that exists as two isozymes, GSK3alpha and GSK3beta. It plays important roles in regulating cell structure, function, and survival, and dysregulation of its function is linked to
Publikováno v:
Cellular Signalling. 16:1405-1415
The molecular signalling pathways governing skeletal muscle differentiation remain unclear. Recent work has demonstrated that both the phosphatidylinositol 3-kinase (PI3K)/Akt and p38 pathways play important roles in myogenesis. Here, we describe the
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C658-C666
The signal transduction pathways connecting cell surface receptors to the activation of muscle-specific promoters and leading to myogenesis are still largely unknown. Recently, a contribution of the p38 mitogen-activated protein kinase (MAPK) pathway
Autor:
Roger Rezzonico, Gilles Ponzio, Karen Yeow, Anne Amandine Chassot, Jean Paul Ortonne, Laurent Turchi, Bernard Ferrua, Agnès Loubat, Gaëlle Le'Negrate
Publikováno v:
Journal of Investigative Dermatology. 119(1):56-63
The aim of this study was to characterize some of the molecular events stimulated in vitro in response to injury within a confluent culture of normal epidermal keratinocytes as a model to understand the mechanisms of wound healing. To this end, an or
Publikováno v:
Canadian Journal of Zoology. 72:2244-2247
We report a method for artificially feeding the reduviid insect Rhodnius prolixus that utilizes heparinized rabbit blood enclosed in an artificial-membrane envelope. Envelopes of Parafilm M® or Nescofilm® are made by heat sealing two pieces, one of
Autor:
Pascale Gaillard, Jean-Pierre Gotteland, Karen Yeow, Paul Lang, Alexander Scheer, ‡ Anne-Marie De Raemy-Schenk, Solenne Troublé, Patrick Page
Publikováno v:
Assay and drug development technologies. 4(5)
Type II diabetes and its associated complications are a major health concern of the developed world. One of the hallmarks of diabetes is insulin resistance, where secreted insulin no longer has any effect on its target tissues, namely, liver, muscle,
Publikováno v:
Nature reviews. Drug discovery. 5(4)
Traditional screening paradigms often focus on single targets. To facilitate drug discovery in the more complex physiological environment of a cell or organism, powerful cellular imaging systems have been developed. The emergence of these detection t
The thrombin receptor in human platelets is coupled to a GTP binding protein of the G alpha q family
Autor:
Laura Cole, Fabrice Roegiers, Mary Lynn Benka, Prabha Dias, Aaron Granger, Michael E. Mendelsohn, Bob Grant, Guang-rong Wang, William B. Busa, Manisha Raje, Oana Marcu, Anda Burlacu, Matt Lee, Adrian Salic, Jennifer Waters, Amanda Hayward-Lester, Sheree Rybak, Judith Yanowitz, Karen Yeow, Jennifer Smith-Hall, Andre Nussenzweig, Sher Karki, Peter Piepenhagen, Ana DePina, Naoyuki Yamamoto, ShaAvhree Buckman, Suzanne Mann
Publikováno v:
FEBS letters. 363(1-2)
The thrombin receptor is a G protein-coupled receptor, but the G proteins functionally coupled to this receptor in human platelets are not yet definitively identified. Thrombin stimulation of platelets leads to phospholipase C-mediated increases in i
Autor:
Karen Yeow, Laurence Novo-Perez, Pascale Gaillard, Patrick Page, Jean-Pierre Gotteland, Alexander Scheer, Paul Lang
Publikováno v:
Assay & Drug Development Technologies; Aug2006, Vol. 4 Issue 4, p451-460, 10p