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pro vyhledávání: '"Karen Whittington"'
Publikováno v:
Current protocolsLiterature Cited. 1(12)
The collagen-induced arthritis mouse model is a widely studied autoimmune model of rheumatoid arthritis. In this model, autoimmune arthritis is induced by immunization of genetically susceptible strains of mice with type II collagen emulsified in com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd61139de1fad9d9a4f7d4763ee9af6
https://pubmed.ncbi.nlm.nih.gov/36005901
https://pubmed.ncbi.nlm.nih.gov/36005901
Autor:
David D Brand, Indra Sandal, Jiwen Luo, Amanda Prislovsky, Karen Whittington, Chen Dong, Edward Rosloniec, Anastasios Karydis
Publikováno v:
The Journal of Immunology. 196:65.29-65.29
Periodontal disease (PD) is a chronic pro-inflammatory response to oral pathogens such as Porphyromonas gingivalis which culminates in alveolar bone loss and loss of dental structure and function. Like rheumatoid arthritis (RA), periodontal disease i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0148e94f7276b3618cfa37395451eb
https://doi.org/10.4049/jimmunol.196.supp.65.29
https://doi.org/10.4049/jimmunol.196.supp.65.29
Publikováno v:
The Journal of Immunology. 186:101.9-101.9
Treg cells play an integral role in preventing autoimmunity, and the enhancement of Treg function is an attractive approach for the treatment of autoimmunity. Toward this goal, we have investigated the efficacy and mechanism of action of FTY720 in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4e78632e09e19400aea9749c481ccc
https://doi.org/10.4049/jimmunol.186.supp.101.9
https://doi.org/10.4049/jimmunol.186.supp.101.9
Publikováno v:
Endocrinology. 128(6)
The aim of this study was to examine insulin and glucagon secretory patterns in successfully transplanted spontaneously diabetic BB/Wor dp rats. Diabetic, BB/Wor dp rats received abdominal, intratesticular islet grafts of MHC-compatible BB/Wor dr don
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35cea393e4f66ad426663ad4a37640e
https://pubmed.ncbi.nlm.nih.gov/1674684
https://pubmed.ncbi.nlm.nih.gov/1674684
Publikováno v:
The Journal of Immunology. 178:S225-S225
Increases in estrogen levels in rheumatoid arthritis (RA) patients result in amelioration of RA symptoms. Similarly, administration of estrogen (17β-estradiol, or E2) decreases incidence of collagen-induced arthritis (CIA), a well-established murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c924999730ae50279a7a46bc6aaf4419
https://doi.org/10.4049/jimmunol.178.supp.129.39
https://doi.org/10.4049/jimmunol.178.supp.129.39
Publikováno v:
Diabetes. 38:220-223
We investigated the survival of islet xenografts in the abdominal testes of normal, diabetes-resistant ACI and Wistar-Lewis (W-L) and in diabetes-prone BB/Wor rats. Islets were isolated from hamster donors, and after a period in tissue culture, they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf0ddc0935a68b15523bd17f88a715
https://doi.org/10.2337/diab.38.1.s220
https://doi.org/10.2337/diab.38.1.s220
Publikováno v:
Diabetes. 34:1019-1024
Thirty-three male BB/W rats with diabetes of 11–145 days duration were divided into 3 groups: (1) six received abdominal, intratesticular islet a I log rafts and no immunosuppression posttransplantation; (2) 15 were similarly grafted and in additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7a40df9e320c545da442046797bbcd
https://doi.org/10.2337/diab.34.10.1019
https://doi.org/10.2337/diab.34.10.1019
Publikováno v:
Diabetes. 36:1061-1067
Transplantation of a large inoculum of incubated islets of MHC-compatible donors led to an extended survival of the grafts to an average of >86 days in 71% of male diabetic BB/W recipients. Identical results were obtained whether the immunologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e951fc97d8fc12d3b3bc9134d1a8c6e5
https://doi.org/10.2337/diabetes.36.9.1061
https://doi.org/10.2337/diabetes.36.9.1061
Autor:
Helena P. Selawry, Karen Whittington
Publikováno v:
Diabetes. 33:405-406
Isolated islets of ACI donor rats were cultured for 4 days at 37°C and then grafted into male diabetic Wistar-Lewis rats into three different organ sites without adjuvant immunosuppression. None of 6 recipients of the intraportal injection of 10 isl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8526eed39842b1c9d9630bea736bd749
https://doi.org/10.2337/diab.33.4.405
https://doi.org/10.2337/diab.33.4.405