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pro vyhledávání: '"Karen Van de Water"'
Autor:
Alexandre Wohlkonig, Alexander N. Volkov, Sameh H. Soror, Karen Van de Water, Nico A. J. van Nuland
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:703-706
TEM-1 β-lactamase is a highly efficient enzyme that is involved in bacterial resistance against β-lactam antibiotics such as penicillin. It is also a robust scaffold protein which can be engineered by molecular-evolution techniques to bind a variet
Publikováno v:
Nature Communications
The complex of yeast cytochrome c peroxidase and cytochrome c is a paradigm of the biological electron transfer (ET). Building on seven decades of research, two different models have been proposed to explain its functional redox activity. One postula
Autor:
David L. Selwood, A. W. Edith Chan, Gabriel Waksman, Alvin W. Lo, Paul J. Gane, Karen Van de Water, David Steadman, Kiri Stevens, Han Remaut
Publikováno v:
Journal of Antimicrobial Chemotherapy
Vrije Universiteit Brussel
Vrije Universiteit Brussel
OBJECTIVES:\ud To identify and to characterize small-molecule inhibitors that target the subunit polymerization of the type 1 pilus assembly in uropathogenic Escherichia coli (UPEC).\ud METHODS:\ud Using an SDS-PAGE-based assay, in silico pre-filtere