Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Karen Taylor-Worth"'
Autor:
Van D. Reif, Stephen C. Eyley, Andrew M. Lipczynski, Simon Golec, Pat Sandra, Kevin L. Facchine, Edward J. Delaney, David P. Elder, Rolf Schulte Oestrich, Wilfried Hoffmann, Andrew Teasdale, Karine Jacq, Karen Taylor-Worth, Frank David
Publikováno v:
Organic Process Research & Development. 14:999-1007
Sulfonate esters of lower alcohols possess the capacity to react with DNA and cause mutagenic events, which in turn may be cancer inducing. Consequently, the control of residues of such substances in products that may be ingested by man (in food or p
Autor:
Stephen C. Eyley, Rolf Schulte Oestrich, David P. Elder, Andrew Teasdale, Karen Taylor-Worth, Ed Delaney, Andrew M. Lipczynski, Frank David, Kevin L. Facchine, Patrick Sandra, Van D. Reif, Karine Jacq, Simon Golec
Publikováno v:
Organic Process Research & Development. 13:429-433
Sulfonate salts offer useful modification of physicochemical properties of active pharmaceutical ingredients (APIs) containing basic groups, but there are regulatory concerns over the presence of sulfonate esters as potential genotoxic impurities (PG
Autor:
Andrew M. Lipczynski, Roberto Alzaga, Karen Taylor-Worth, Robert W. Ryan, Roman Szucs, Pat Sandra
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 45:472-479
A simple, reliable and fast procedure for the simultaneous determination of residues of some common alkylating agents (AAs), such as mesylates, besylates, tosylates and sulfates, employed in drug synthesis, has been developed by in situ derivatizatio
Autor:
Andrew M. Lipczynski, Pat Sandra, Andrew Teasdale, Simon Golec, Kevin L. Facchine, Karine Jacq, Ed Delaney, Karen Taylor-Worth, Steve Eyley, Van D. Reif, Rolf Schulte Oestrich, Frank David, David P. Elder
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 48(5)
An automated sample preparation and analysis procedure was developed to monitor the formation of ethyl methane sulfonate from reaction mixtures containing ethanol and methane sulfonic acid. The system is based on a liquid handling robot combined with
Autor:
Andrew Teasdale, Stephen C. Eyley, Ed Delaney, Karine Jacq, Karen Taylor-Worth, Andrew Lipczynski, Van Reif, David P. Elder, Kevin L. Facchine, Simon Golec, Rolf Schulte Oestrich, Pat Sandra, Frank David
Publikováno v:
Organic Process Research & Development; May2009, Vol. 13 Issue 3, p429-433, 5p