Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karen Sokol"'
Autor:
L. Delta Merner, Lisa Benjamin, William Ercole, Isabela Keuschnigg, Julian Kunik, Karla Martínez Toral, Laura Peterson, Joana Setzer, Karen Sokol, Aradhna Tandon, Kaia Turowski
Publikováno v:
Carbon Management, Vol 15, Iss 1 (2024)
AbstractAmid mushrooming net-zero commitments and pledges made by states and non-state entities, a gap remains between those pledges, and the action needed in order to stay within the temperature goals of the Paris Agreement. In response, scholars an
Externí odkaz:
https://doaj.org/article/0e4bcc6062eb4f4cb1c4373a4df84300
Autor:
Colton Ladbury, Claire Hao, William Tyler Watkins, Sagus Sampath, Jeffrey Wong, Arya Amini, Karen Sokolov, Jekwon Yeh, Karine A. Al Feghali, Dorine de Jong, Arjun Maniyedath, Shervin Shirvani, Liana Nikolaenko, Matthew Mei, Alex Herrera, Leslie Popplewell, Lihua Elizabeth Budde, Savita Dandapani
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Purpose/objective(s)Bridging radiation therapy (bRT) is increasingly being utilized prior to chimeric antigen receptor (CAR) T-cell therapy for large B-cell lymphoma (LBCL). It is unknown how the extent of cytoreduction during bRT impacts outcomes.Ma
Externí odkaz:
https://doaj.org/article/502c60fc675a43be8a7a55a5466af5ee
Autor:
Karen Sokol, Margaret Burroughs, Liana Tsenova-Berkova, Gilla Kaplan, Elaine Tuomanen, Joachim Ossig
Publikováno v:
Microbial Pathogenesis. 19:245-255
In experimental bacterial meningitis in rabbits, the inflammatory process is largely mediated by cytokines such as IL-1 and TNF-alpha. Since thalidomide has been shown to inhibit TNF-alpha production, experiments were carried out to determine whether
Autor:
Myrna E. Trumbauer, Daniel S. Fletcher, Karen Sokol, Qiao-wen Xie, Gary J Hom, Carl Nathan, Karla Stevens, John D. MacMicking, Nicole A. Chartrain, John S. Mudget, Nancy I. Hutchinson, Howard Y. Chen
Publikováno v:
Cell. 81(4):641-650
Mice deficient in inducible nitric oxide synthase (iNOS) were generated to test the idea that !NOS defends the host against infectious agents and tumor cells at the risk of contributing to tissue damage and shock. iNOS -I- mice failed to restrain the
Publikováno v:
Contemporary topics in laboratory animal science. 42(6)
Supraphysiological 17beta-estradiol treatment administered via subcutaneous pellets is commonly used in mice. However, despite its efficacy in eliciting a uterotrophic response, we demonstrate that this regimen also was associated with urine retentio
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 39(1)
Infection is the most serious complication arising in long-term continuous ambulatory peritoneal dialysis (CAPD), specifically peritonitis and exit-site infection. The initial weeks after implantation is the crucial period during which bacterial colo
Autor:
Wei Weng, Tanya Shiyanova, William S. Chen, Mei Ling Chen, Ryo Suzuki, Pei Zhang Xu, Kathrin Gottlob, Karen Sokol, Igor B. Roninson, Nissim Hay, Takashi Kadowaki, Kazuyuki Tobe
The serine/threonine kinase Akt has been implicated in the control of cell survival and metabolism. Here we report the disruption of the most ubiquitously expressed member of theakt family of genes, akt1, in the mouse. Akt1−/− mice are viable but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd737df382b1d13eca0d11b3b95547e4
https://europepmc.org/articles/PMC312770/
https://europepmc.org/articles/PMC312770/
Autor:
Soo Young Lee, Angela Santana, Yongwon Choi, Karen Sokol, Amy Reichlin, Michel C. Nussenzweig
Publikováno v:
Immunity. 7(5)
TRAF2 is believed to mediate the activation of NF-kappaB and JNK induced by the tumor necrosis factor receptor (TNFR) superfamily, which elicits pleiotropic responses in lymphocytes. We have investigated the physiological roles of TRAF2 in these proc
Autor:
Paul M. Simon, Ilona Idanpaan-Heikkila, David Zopf, Karen Sokol, Thomas Vullo, Patrick T. Cahill, Elaine Tuomanen
Publikováno v:
The Journal of infectious diseases. 176(3)
Oligosaccharides that block the adherence of bacteria to epithelial cells in vitro--lacto-N-neotetraose (LNnT) and its alpha2-3- and alpha2-6-sialylated derivatives--were tested for their abilities to attenuate the course of pneumococcal pneumonia an
Publikováno v:
Immunity. 1(2)
RAG -1 and RAG -2 are developmentally regulated genes that are essential for the assembly of antigen receptors in lymphoid cells. Here we describe transgenic mice that carry RAG -1 and RAG -2 under the control of the proximal Ick promoter. Persistent