Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Karen Saye"'
Autor:
Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V. Guryleva, Roberta P. Fuller, Torben Schiffner, Justin R. Abadejos, Lauren Couvrette, Tanya R. Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia Gonzalez-Martin, William Schief, Ben Murrell, Dennis R. Burton, David Nemazee, James E. Voss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
A vaccine to generate durable HIV broadly neutralizing antibodies (bnAb) from engineered B cells holds promise as an HIV functional cure. Here, the authors show that CRISPR/Cas-modified B cells expressing bnAbs as functional antigen receptors can be
Externí odkaz:
https://doaj.org/article/8f0e41a577a24e6390766e0efaf6153c
Autor:
Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V. Guryleva, Roberta P. Fuller, Torben Schiffner, Justin R. Abadejos, Lauren Couvrette, Tanya R. Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia Gonzalez-Martin, William Schief, Ben Murrell, Dennis R. Burton, David Nemazee, James E. Voss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20304-y
Externí odkaz:
https://doaj.org/article/d00cdcb7706c4616af3cfef8ada576ca
Autor:
Charles D. Morris, Parisa Azadnia, Natalia de Val, Nemil Vora, Andrew Honda, Erick Giang, Karen Saye-Francisco, Yushao Cheng, Xiaohe Lin, Colin J. Mann, Jeffrey Tang, Devin Sok, Dennis R. Burton, Mansun Law, Andrew B. Ward, Linling He, Jiang Zhu
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Broadly neutralizing antibodies (bNAbs) have provided valuable insights into the humoral immune response to HIV-1. While rationally designed epitope scaffolds and well-folded gp140 trimers have been proposed as vaccine antigens, a comparativ
Externí odkaz:
https://doaj.org/article/dbe193c7017d4d1bb2b716e824357db2
Autor:
Jenny Tuyet Tran, Thomas Vollbrecht, Tanya R. Blane, Roberta P. Fuller, Deli Huang, Mariia V. Guryleva, William R. Schief, Alicia Gonzalez-Martin, David Nemazee, Ben Murrell, Karen Saye, Lauren Couvrette, Alex Olson, Torben Schiffner, Dennis R. Burton, Justin R. Abadejos, Wenjuan Li, James E. Voss, Mary Tenuta, Elise Landais
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
HIV broadly neutralizing antibodies (bnAbs) can suppress viremia and protect against HIV infection. However, their elicitation is made difficult by low frequencies of appropriate precursor B cell receptors and the complex maturation pathways required