Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karen S Kim Guisbert"'
Autor:
Janneke Wit, Clayton M Dilks, Gaotian Zhang, Karen S Kim Guisbert, Stefan Zdraljevic, Eric Guisbert, Erik C Andersen
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0286473 (2023)
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans and other animals. Caenorhabditis elegans is an established model to investigate anthelmintics used to treat roundworms. In this study, we use C. elegans to ex
Externí odkaz:
https://doaj.org/article/2907aa0343684d1e9cc9aed2285f07b4
Autor:
Karen S Kim Guisbert, Eric Guisbert
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176382 (2017)
The heat shock response (HSR) is a well-conserved, cytoprotective stress response that activates the HSF1 transcription factor. During severe stress, cells inhibit mRNA splicing which also serves a cytoprotective function via inhibition of gene expre
Externí odkaz:
https://doaj.org/article/aa8a98700e0240339823f731336ee15d
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105058 (2014)
In Saccharomyces cerevisiae, meiosis and sporulation are highly regulated responses that are driven in part by changes in RNA expression. Alternative mRNA forms with extended 5' UTRs are atypical in S. cerevisiae, and 5' extensions with upstream open
Externí odkaz:
https://doaj.org/article/d20f1b7928814a63ba3e591700c9a985
Publikováno v:
PLoS Biology, Vol 5, Iss 1, p e6 (2007)
The Saccharomyces cerevisiae RNA-binding protein Nab4/Hrp1 is a component of the cleavage factor complex required for 3' pre-mRNA processing. Although the precise role of Nab4/Hrp1 remains unclear, it has been implicated in correct positioning of the
Externí odkaz:
https://doaj.org/article/acb23e6d7b7745ac9cf7225809fcd00a
Autor:
Janneke Wit, Clayton M. Dilks, Gaotian Zhang, Karen S. Kim Guisbert, Stefan Zdraljevic, Eric Guisbert, Erik C. Andersen
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans and other animals.Caenorhabditis elegansis an established model to investigate anthelmintics used to treat roundworms. In this study, we useC. elegansto examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c69e90841d42c94e1cdfc234a3cec557
https://doi.org/10.1101/2023.05.17.541211
https://doi.org/10.1101/2023.05.17.541211
Autor:
Isiah Mossiah, Sabrina M. Perez, Taylor R. Stanley, Michaela K. Foley, Karen S. Kim Guisbert, Eric Guisbert
Publikováno v:
Frontiers in Aging. 3
Activation of a cytoprotective cellular pathway known as the heat shock response (HSR) is a promising strategy for the treatment of Alzheimer’s disease and other neurodegenerative diseases. Geranylgeranylacetone (GGA) is a commonly used anti-ulcer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca15803a93dc86ac250db83454651e26
https://doi.org/10.3389/fragi.2022.846977
https://doi.org/10.3389/fragi.2022.846977
Autor:
Taylor R. Stanley, Karen S. Kim Guisbert, Sabrina M. Perez, Morgan Oneka, Isabela Kernin, Nicole R. Higgins, Alexandra Lobo, Munevver M. Subasi, David J. Carroll, Ralph G. Turingan, Eric Guisbert
Publikováno v:
J Exp Biol
The bluegill sunfish Lepomis macrochirus and the closely related redear sunfish Lepomis microlophus have important ecological and recreational value and are widely used for research and aquaculture. While both species have been introduced outside of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2740923b62fd254174f0c252aba97cc8
https://doi.org/10.1242/jeb.243263
https://doi.org/10.1242/jeb.243263
Autor:
Isiah, Mossiah, Sabrina M, Perez, Taylor R, Stanley, Michaela K, Foley, Karen S, Kim Guisbert, Eric, Guisbert
Publikováno v:
Frontiers in aging. 3
Activation of a cytoprotective cellular pathway known as the heat shock response (HSR) is a promising strategy for the treatment of Alzheimer's disease and other neurodegenerative diseases. Geranylgeranylacetone (GGA) is a commonly used anti-ulcer dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94119988036c42ae1b9898cb2b7f3fd2
https://pubmed.ncbi.nlm.nih.gov/35821801
https://pubmed.ncbi.nlm.nih.gov/35821801
Publikováno v:
BMC Biology
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
BMC Biology, Vol 19, Iss 1, Pp 1-14 (2021)
BackgroundTemperature influences biology at all levels, from altering rates of biochemical reactions to determining sustainability of entire ecosystems. Although extended exposure to elevated temperatures influences organismal phenotypes important fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6a3dbf298b4d9c34395b9f2ae9e3b6
https://pubmed.ncbi.nlm.nih.gov/33858388
https://pubmed.ncbi.nlm.nih.gov/33858388
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9641, p 9641 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9641, p 9641 (2020)
SF3B1 is a core component of the U2 spliceosome that is frequently mutated in cancer. We have previously shown that titrating the activity of SF3B1, using the inhibitor pladienolide B (PB), affects distinct steps of the heat shock response (HSR). Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bb16a7a64802e6e678abe8f65cd863