Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Karen S, Sfanos"'
Autor:
Thiago Vidotto, Eddie L. Imada, Farzana Faisal, Sanjana Murali, Adrianna A. Mendes, Harsimar Kaur, Siqun Zheng, Jianfeng Xu, Edward M. Schaeffer, William B. Isaacs, Karen S. Sfanos, Luigi Marchionni, Tamara L. Lotan
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
The genomic and immune landscapes of prostate cancer differ by self-identified race. However, few studies have examined the genome-wide copy number landscape and immune content of matched cohorts with genetic ancestry data and clinical outcomes. Here
Externí odkaz:
https://doaj.org/article/ecd843645058485e9f5dc48d24f26852
Autor:
Lauren B. Peiffer, James R. White, Carli B. Jones, Rachel E. Slottke, Sarah E. Ernst, Amy E. Moran, Julie N. Graff, Karen S. Sfanos
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100822- (2022)
Recent studies in cancer patients and animal models demonstrate that intestinal microbiota influence the therapeutic efficacy of cancer treatments, including immune checkpoint inhibition. However, no studies to-date have investigated relationships be
Externí odkaz:
https://doaj.org/article/e3769f5586d74baa8303d87a6c921ba4
Autor:
Lauren B. Peiffer, Jessica Hicks, Rebecca Y. Sosa, Angelo M. De Marzo, Karen S. Sfanos, Janielle P. Maynard
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The 5-year survival rate for patients diagnosed with distant metastatic prostate cancer in the United States is 30.6%. Therefore, there is a great need to develop in vivo model systems to study prostate cancer metastasis and to test potential therape
Externí odkaz:
https://doaj.org/article/d5fb3d77abd240289fd047095a2786a4
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Short read 16 S rRNA amplicon sequencing is a common technique used in microbiome research. However, inaccuracies in estimated bacterial community composition can occur due to amplification bias of the targeted hypervariable region. A potential solut
Externí odkaz:
https://doaj.org/article/f13badecf90c403c94baacef2e91c574
Autor:
William G. Nelson, Otis W. Brawley, William B. Isaacs, Elizabeth A. Platz, Srinivasan Yegnasubramanian, Karen S. Sfanos, Tamara L. Lotan, Angelo M. De Marzo
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Prostate cancer exerts a greater toll on African American men than on White men of European descent (hereafter referred to as European American men): the disparity in incidence and mortality is greater than that of any other common cancer. The dispro
Externí odkaz:
https://doaj.org/article/efe4325533a14b22bf895c05a7fb49fa
Autor:
Laura M. Wake MD, Derek B. Allison MD, Alisha D. Ware MD, Jody E. Hooper MD, Alex S. Baras MD, PhD, Evan M. Bloch MBChB, MS, William Clarke PhD, Kathleen H. Burns MD, PhD, Karen S. Sfanos MS, PhD, Michael J. Borowitz MD, PhD, Charles Steenbergen MD, PhD, Ralph H. Hruban MD, Marissa J. White MD
Publikováno v:
Academic Pathology, Vol 8 (2021)
Pathologists who enter the workforce must have a diverse skill set beyond that of clinical diagnostics alone. Anticipating this need, the Johns Hopkins Pathology Residency Program developed Special Expertise Tracks to enhance training in relevant sub
Externí odkaz:
https://doaj.org/article/a86339f24c504feabc4054c257fe2eee
Autor:
Claire Guest, Rob Harris, Karen S Sfanos, Eva Shrestha, Alan W Partin, Bruce Trock, Leslie Mangold, Rebecca Bader, Adam Kozak, Scott Mclean, Jonathan Simons, Howard Soule, Thomas Johnson, Wen-Yee Lee, Qin Gao, Sophie Aziz, Patritsia Maria Stathatou, Stephen Thaler, Simmie Foster, Andreas Mershin
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245530 (2021)
Prostate cancer is the second leading cause of cancer death in men in the developed world. A more sensitive and specific detection strategy for lethal prostate cancer beyond serum prostate specific antigen (PSA) population screening is urgently neede
Externí odkaz:
https://doaj.org/article/1d622d5373d9440f92945dcf1d37975c
Autor:
Igor Vidal, Qizhi Zheng, Jessica L Hicks, Jiayu Chen, Elizabeth A Platz, Bruce J Trock, Ibrahim Kulac, Javier A Baena-Del Valle, Karen S Sfanos, Sarah Ernst, Tracy Jones, Janielle P Maynard, Stephanie A Glavaris, William G Nelson, Srinivasan Yegnasubramanian, Angelo M De Marzo
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0241934 (2021)
GSTP1 is a member of the Glutathione-S-transferase (GST) family silenced by CpG island DNA hypermethylation in 90-95% of prostate cancers. However, prostate cancers expressing GSTP1 have not been well characterized. We used immunohistochemistry again
Externí odkaz:
https://doaj.org/article/f8b82cf97d47488885f04952aabfccf4
Autor:
Karen S. Sfanos, Srinivasan Yegnasubramanian, William G. Nelson, Tamara L. Lotan, Ibrahim Kulac, Jessica L. Hicks, Qizhi Zheng, Charles J. Bieberich, Michael C. Haffner, Angelo M. De Marzo
Publikováno v:
Asian Journal of Urology, Vol 6, Iss 1, Pp 10-25 (2019)
Antibodies are employed ubiquitously in biomedical sciences, including for diagnostics and therapeutics. One of the most important uses is for immunohistochemical (IHC) staining, a process that has been improving and evolving over decades. IHC is use
Externí odkaz:
https://doaj.org/article/f9f935aa6f6f4a879ea3a168a7fbf4b6
Autor:
Janielle P. Maynard, Taylor N. Godwin, Jiayun Lu, Igor Vidal, Tamara L. Lotan, Angelo M. De Marzo, Corinne E. Joshu, Karen S. Sfanos
Publikováno v:
The Prostate. 82:1505-1519
Black men are two to three times more likely to die from prostate cancer (PCa) than White men. This disparity is due in part to discrepancies in socioeconomic status and access to quality care. Studies also suggest that differences in the prevalence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad4d6b39fe12b4dcbdda586f5ba2954
https://doi.org/10.1002/pros.24424
https://doi.org/10.1002/pros.24424